KEGG   PATHWAY: hsa00640Help
Entry
hsa00640                    Pathway                                

Name
Propanoate metabolism - Homo sapiens (human)
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
Propanoate metabolism
hsa00640

All organismsOrtholog table
Module
Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH:hsa00640]
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hsa00640]
Disease
H00174  
Methylmalonic aciduria (MMA)
H00175  
Propionic acidemia
H01283  
Malonyl-CoA decarboxylase deficiency
Drug
D00399  
Valproic acid (USP)
D00535  
Vigabatrin (JAN/USAN/INN)
D00710  
Valproate sodium (USAN)
D08667  
Calcium valproate
Other DBs
BSID: 
GO: 
Organism
Homo sapiens (human) [GN:hsa]
Gene
84532  
ACSS1; acyl-CoA synthetase short-chain family member 1 [KO:K01895] [EC:6.2.1.1]
55902  
ACSS2; acyl-CoA synthetase short-chain family member 2 [KO:K01895] [EC:6.2.1.1]
79611  
ACSS3; acyl-CoA synthetase short-chain family member 3 [KO:K01908] [EC:6.2.1.17]
593  
BCKDHA; branched chain keto acid dehydrogenase E1, alpha polypeptide [KO:K00166] [EC:1.2.4.4]
594  
BCKDHB; branched chain keto acid dehydrogenase E1 subunit beta [KO:K00167] [EC:1.2.4.4]
1629  
DBT; dihydrolipoamide branched chain transacylase E2 [KO:K09699] [EC:2.3.1.168]
1738  
DLD; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
34  
ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain [KO:K00249] [EC:1.3.8.7]
3030  
HADHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit [KO:K07515] [EC:1.1.1.211 4.2.1.17]
1962  
EHHADH; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase [KO:K07514] [EC:5.3.3.8 1.1.1.35 4.2.1.17]
1892  
ECHS1; enoyl-CoA hydratase, short chain 1 [KO:K07511] [EC:4.2.1.17]
26275  
HIBCH; 3-hydroxyisobutyryl-CoA hydrolase [KO:K05605] [EC:3.1.2.4]
31  
ACACA; acetyl-CoA carboxylase alpha [KO:K11262] [EC:6.3.4.14 6.4.1.2]
32  
ACACB; acetyl-CoA carboxylase beta [KO:K01946] [EC:6.3.4.14 6.4.1.2]
23417  
MLYCD; malonyl-CoA decarboxylase [KO:K01578] [EC:4.1.1.9]
18  
ABAT; 4-aminobutyrate aminotransferase [KO:K13524] [EC:2.6.1.22 2.6.1.19]
5095  
PCCA; propionyl-CoA carboxylase alpha subunit [KO:K01965] [EC:6.4.1.3]
5096  
PCCB; propionyl-CoA carboxylase beta subunit [KO:K01966] [EC:6.4.1.3]
55862  
ECHDC1; ethylmalonyl-CoA decarboxylase 1 [KO:K18426] [EC:4.1.1.41 4.1.1.94]
84693  
MCEE; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
4594  
MUT; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
8802  
SUCLG1; succinate-CoA ligase alpha subunit [KO:K01899] [EC:6.2.1.5 6.2.1.4]
8801  
SUCLG2; succinate-CoA ligase GDP-forming beta subunit [KO:K01900] [EC:6.2.1.5 6.2.1.4]
8803  
SUCLA2; succinate-CoA ligase ADP-forming beta subunit [KO:K01900] [EC:6.2.1.5 6.2.1.4]
4329  
ALDH6A1; aldehyde dehydrogenase 6 family member A1 [KO:K00140] [EC:1.2.1.27 1.2.1.18]
160287  
LDHAL6A; lactate dehydrogenase A like 6A [KO:K00016] [EC:1.1.1.27]
92483  
LDHAL6B; lactate dehydrogenase A like 6B [KO:K00016] [EC:1.1.1.27]
3939  
LDHA; lactate dehydrogenase A [KO:K00016] [EC:1.1.1.27]
3945  
LDHB; lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
3948  
LDHC; lactate dehydrogenase C [KO:K00016] [EC:1.1.1.27]
39  
ACAT2; acetyl-CoA acetyltransferase 2 [KO:K00626] [EC:2.3.1.9]
38  
ACAT1; acetyl-CoA acetyltransferase 1 [KO:K00626] [EC:2.3.1.9]
Compound
C00024  
Acetyl-CoA
C00033  
Acetate
C00042  
Succinate
C00068  
Thiamin diphosphate
C00083  
Malonyl-CoA
C00091  
Succinyl-CoA
C00099  
beta-Alanine
C00100  
Propanoyl-CoA
C00109  
2-Oxobutanoate
C00111  
Glycerone phosphate
C00132  
Methanol
C00163  
Propanoate
C00164  
Acetoacetate
C00186  
(S)-Lactate
C00207  
Acetone
C00222  
3-Oxopropanoate
C00332  
Acetoacetyl-CoA
C00424  
(S)-Lactaldehyde
C00479  
Propanal
C00546  
Methylglyoxal
C00583  
Propane-1,2-diol
C00683  
(S)-Methylmalonyl-CoA
C00804  
Propynoate
C00827  
Lactoyl-CoA
C00894  
Propenoyl-CoA
C01013  
3-Hydroxypropanoate
C01213  
(R)-Methylmalonyl-CoA
C01845  
Propan-2-ol
C02170  
Methylmalonate
C02225  
2-Methylcitrate
C02335  
beta-Alanyl-CoA
C02876  
Propanoyl phosphate
C04225  
(Z)-But-2-ene-1,2,3-tricarboxylate
C04593  
(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate
C05235  
Hydroxyacetone
C05668  
3-Hydroxypropionyl-CoA
C05979  
Propane-1-ol
C05983  
Propionyladenylate
C05984  
2-Hydroxybutanoic acid
C05989  
3-Oxopropionyl-CoA
C06002  
(S)-Methylmalonate semialdehyde
C15972  
Enzyme N6-(lipoyl)lysine
C15973  
Enzyme N6-(dihydrolipoyl)lysine
C17530  
Methyl acetate
C20783  
Propane
C21017  
2-(alpha-Hydroxypropyl)thiamine diphosphate
C21018  
Enzyme N6-(S-propyldihydrolipoyl)lysine
C21250  
2-Methyl-trans-aconitate
KO pathway
 

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