KEGG PATHWAY: hsl00230

PATHWAY: hsl00230

Entry

hsl00230 Pathway

Name

Purine metabolism - Halobacterium salinarum R1

Class

Metabolism; Nucleotide metabolism

Pathway map

hsl00230

Purine metabolism

Module

hsl_M00005	PRPP biosynthesis, ribose 5P => PRPP [PATH:hsl00230]
hsl_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:hsl00230]
hsl_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hsl00230]
hsl_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:hsl00230]
hsl_M00546	Purine degradation, xanthine => urea [PATH:hsl00230]

Other DBs

BSID:

64680

GO:

0042278

Organism

Halobacterium salinarum R1 [GN:hsl]

Gene

OE4621F	nudF1; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13]
OE3752R	nudF2; nudix family protein [KO:K01515] [EC:3.6.1.13]
OE4094F	pmm1; phosphohexomutase (phosphoglucomutase,phosphomannomutase) [KO:K15778] [EC:5.4.2.2 5.4.2.8]
OE4085R	prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
OE3139R	purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
OE2864F	purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
OE2274R	purL; phosphoribosylformylglycinamidine synthase II [KO:K01952] [EC:6.3.5.3]
OE3731R	purQ; phosphoribosylformylglycinamidine synthase I [KO:K01952] [EC:6.3.5.3]
OE3732R	purS; phosphoribosylformylglycinamidine synthase component purS [KO:K01952] [EC:6.3.5.3]
OE2292F	purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
OE1951F	purK; phosphoribosylaminoimidazole carboxylase carbon dioxide-fixation subunit [KO:K01589] [EC:6.3.4.18]
OE1952F	purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
OE3724F	purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
OE1623F	purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
OE1620R	purNH; phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
OE4329F	purO; IMP cyclohydrolase [KO:K11176] [EC:3.5.4.10]
OE1840R	apt1; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
OE3951R	apt2; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
OE2782F	surE; stationary-phase survival protein [KO:K03787] [EC:3.1.3.5]
OE2458R	guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
OE1969F	CBS/parB domain-containing protein; K00088 IMP dehydrogenase [EC:1.1.1.205] [KO:K00088] [EC:1.1.1.205]
OE2667F	ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
OE3863R	ham1; 6-N-hydroxylaminopurine sensitivity-controlling protein [KO:K02428] [EC:3.6.1.19]
OE3571R	guaAb; GMP synthase subunit B [KO:K01951] [EC:6.3.5.2]
OE4502R	guaA; glutamine amidotransferase ( GMP synthase subunit A) [KO:K01951] [EC:6.3.5.2]
OE1363F	guaAa; GMP synthase subunit A [KO:K01951] [EC:6.3.5.2]
OE1495R	pykA; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
OE4346R	nrdA1; ribonucleoside-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
OE3328R	nrdA2; ribonucleoside-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
OE4345R	nrdB1; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
OE4739R	rpoA2; DNA-directed RNA polymerase subunit A'' [KO:K03042] [EC:2.7.7.6]
OE4740R	rpoA1; DNA-directed RNA polymerase subunit A' [KO:K03041] [EC:2.7.7.6]
OE4741R	rpoB1; DNA-directed RNA polymerase subunit B' [KO:K03044] [EC:2.7.7.6]
OE4742R	rpoB2; DNA-directed RNA polymerase subunit beta'' [KO:K03045] [EC:2.7.7.6]
OE4743R	rpoH; DNA-directed RNA polymerase subunit H [KO:K03053] [EC:2.7.7.6]
OE2638F	rpoK; DNA-directed RNA polymerase subunit K [KO:K03055] [EC:2.7.7.6]
OE2637F	rpoN; DNA-directed RNA polymerase subunit N [KO:K03058] [EC:2.7.7.6]
OE2631F	rpoD; DNA-directed RNA polymerase subunit D [KO:K03047] [EC:2.7.7.6]
OE3874R	rpoE1; DNA-directed RNA polymerase subunit E' [KO:K03049] [EC:2.7.7.6]
OE3872R	rpoE2; DNA-directed RNA polymerase subunit E'' [KO:K03050] [EC:2.7.7.6]
OE2267F	rpoL; DNA-directed RNA polymerase subunit L [KO:K03056] [EC:2.7.7.6]
OE1372R	rpoP; DNA-directed RNA polymerase subunit P [KO:K03059] [EC:2.7.7.6]
OE2678R	rpoF; DNA-directed RNA polymerase subunit F [KO:K03051] [EC:2.7.7.6]
OE6234F	polB3b; DNA polymerase I [KO:K02319] [EC:2.7.7.7]
OE7114F	polB3a; DNA polymerase I [KO:K02319] [EC:2.7.7.7]
OE6036F	polB2; DNA polymerase I [KO:K02319] [EC:2.7.7.7]
OE4293R	polA2; DNA polymerase II large subunit [KO:K02322] [EC:2.7.7.7]
OE4390F	polA1; DNA polymerase II small subunit [KO:K02323] [EC:2.7.7.7]
OE4163R	DNA primase large subunit; K02685 DNA primase large subunit [EC:2.7.7.-] [KO:K02685] [EC:2.7.7.-]
OE2856F	cyaB; adenylate cyclase [KO:K05873] [EC:4.6.1.1]
OE2579F	purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
OE3425F	adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
OE5206R	arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]

Compound

C00002	ATP
C00008	ADP
C00011	CO2
C00014	NH3
C00020	AMP
C00035	GDP
C00037	Glycine
C00039	DNA
C00044	GTP
C00046	RNA
C00048	Glyoxylate
C00053	3'-Phosphoadenylyl sulfate
C00054	Adenosine 3',5'-bisphosphate
C00059	Sulfate
C00064	L-Glutamine
C00081	ITP
C00086	Urea
C00104	IDP
C00117	D-Ribose 5-phosphate
C00119	5-Phospho-alpha-D-ribose 1-diphosphate
C00130	IMP
C00131	dATP
C00144	GMP
C00147	Adenine
C00169	Carbamoyl phosphate
C00206	dADP
C00212	Adenosine
C00224	Adenylyl sulfate
C00242	Guanine
C00262	Hypoxanthine
C00286	dGTP
C00294	Inosine
C00301	ADP-ribose
C00330	Deoxyguanosine
C00360	dAMP
C00361	dGDP
C00362	dGMP
C00366	Urate
C00385	Xanthine
C00387	Guanosine
C00499	Allantoate
C00559	Deoxyadenosine
C00575	3',5'-Cyclic AMP
C00603	(-)-Ureidoglycolate
C00620	alpha-D-Ribose 1-phosphate
C00655	Xanthosine 5'-phosphate
C00700	XTP
C00802	Oxalureate
C00942	3',5'-Cyclic GMP
C01228	Guanosine 3',5'-bis(diphosphate)
C01260	P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261	P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344	dIDP
C01345	dITP
C01367	3'-AMP
C01762	Xanthosine
C02091	(S)-Ureidoglycine
C02348	(R)(-)-Allantoin
C02350	(S)(+)-Allantoin
C02353	2',3'-Cyclic AMP
C02718	N-Formiminoglycine
C03090	5-Phosphoribosylamine
C03373	Aminoimidazole ribotide
C03483	Adenosine tetraphosphate
C03614	Inosine 5'-tetraphosphate
C03794	N6-(1,2-Dicarboxyethyl)-AMP
C03838	5'-Phosphoribosylglycinamide
C04051	5-Amino-4-imidazolecarboxyamide
C04376	5'-Phosphoribosyl-N-formylglycinamide
C04392	P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494	Guanosine 3'-diphosphate 5'-triphosphate
C04640	2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677	1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734	1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751	1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823	1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239	5-Aminoimidazole
C05512	Deoxyinosine
C05513	Urate-3-ribonucleoside
C05515	5-Ureido-4-imidazole carboxylate
C05516	5-Amino-4-imidazole carboxylate
C05993	Acetyl adenylate
C06193	Guanosine 3'-phosphate
C06194	2',3'-Cyclic GMP
C06195	Imidazolone
C06196	2'-Deoxyinosine 5'-phosphate
C06197	P1,P3-Bis(5'-adenosyl) triphosphate
C06433	5'-Benzoylphosphoadenosine
C06435	5'-Butyrylphosphoinosine
C11821	5-Hydroxyisourate
C12248	5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667	5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole

Reference

PMID:10601204

Authors

Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.

Title

Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Journal

J Bacteriol 181:7479-84 (1999)

Reference

PMID:10986234

Authors

Xi H, Schneider BL, Reitzer L.

Title

Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.

Journal

J Bacteriol 182:5332-41 (2000)

KO pathway

ko00230

All links

Pathway (3)   
   KEGG MODULE (2)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (53)   
   KEGG GENES (53)   
All databases (57)   

Download RDF

DBGET integrated database retrieval system