KEGG   PATHWAY: hsl00230Help
Entry
hsl00230                    Pathway                                

Name
Purine metabolism - Halobacterium salinarum
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
hsl00230  Purine metabolism
hsl00230

Ortholog table
Module
hsl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hsl00230]
hsl_M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:hsl00230]
hsl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hsl00230]
Other DBs
BSID: 64680
GO: 0042278
Organism
Halobacterium salinarum [GN:hsl]
Gene
OE_4621F  NUDIX family hydrolase [KO:K01515] [EC:3.6.1.13]
OE_3752R  NUDIX family hydrolase [KO:K01515] [EC:3.6.1.13]
OE_4094F  pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) [KO:K15778] [EC:5.4.2.2 5.4.2.8]
OE_4085R  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
OE_3139R  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
OE_2864F  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
OE_1620R  purNH; phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K01492] [EC:2.1.2.3 2.1.2.2]
OE_2274R  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K01952] [EC:6.3.5.3]
OE_3731R  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K01952] [EC:6.3.5.3]
OE_3732R  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K01952] [EC:6.3.5.3]
OE_2292F  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
OE_1951F  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
OE_1952F  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
OE_3724F  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
OE_1623F  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
OE_4329F  purO; inosine-5'-monophosphate cyclohydrolase, archaeal-type [KO:K11176] [EC:3.5.4.10]
OE_1840R  apt1; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) [KO:K00759] [EC:2.4.2.7]
OE_3951R  apt2; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) [KO:K00759] [EC:2.4.2.7]
OE_2782F  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5]
OE_2458R  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
OE_2667F  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
OE_3863R  ham1; non-canonical purine NTP pyrophosphatase [KO:K02428] [EC:3.6.1.66]
OE_3571R  guaAb; GMP synthase (glutamine-hydrolyzing) subunit B [KO:K01951] [EC:6.3.5.2]
OE_4502R  guaAa2; glutamine amidotransferase (homolog to GMP synthase subunit A) [KO:K01951] [EC:6.3.5.2]
OE_1363F  guaAa1; GMP synthase (glutamine-hydrolyzing) subunit A [KO:K01951] [EC:6.3.5.2]
OE_1495R  pykA; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
OE_4346R  nrdA1; ribonucleoside-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
OE_3328R  nrdJ; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
OE_4345R  nrdB1; ribonucleoside-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
OE_4739R  rpoA2; DNA-directed RNA polymerase subunit A'' [KO:K03042] [EC:2.7.7.6]
OE_4740R  rpoA1; DNA-directed RNA polymerase subunit A' [KO:K03041] [EC:2.7.7.6]
OE_4741R  rpoB1; DNA-directed RNA polymerase subunit B' [KO:K03044] [EC:2.7.7.6]
OE_4742R  rpoB2; DNA-directed RNA polymerase subunit B'' [KO:K03045] [EC:2.7.7.6]
OE_4743R  rpoH; DNA-directed RNA polymerase subunit H [KO:K03053] [EC:2.7.7.6]
OE_2638F  rpoK; DNA-directed RNA polymerase subunit K [KO:K03055] [EC:2.7.7.6]
OE_2637F  rpoN; DNA-directed RNA polymerase subunit N [KO:K03058] [EC:2.7.7.6]
OE_2631F  rpoD; DNA-directed RNA polymerase subunit D [KO:K03047] [EC:2.7.7.6]
OE_3874R  rpoE1; DNA-directed RNA polymerase subunit E [KO:K03049] [EC:2.7.7.6]
OE_3872R  spt4; transcription elongation factor Spt4 [KO:K03050] [EC:2.7.7.6]
OE_2267F  rpoL; DNA-directed RNA polymerase subunit L [KO:K03056] [EC:2.7.7.6]
OE_1372R  rpoP; DNA-directed RNA polymerase subunit P [KO:K03059] [EC:2.7.7.6]
OE_2678R  rpoF; DNA-directed RNA polymerase subunit F [KO:K03051] [EC:2.7.7.6]
OE_6234F  polB3b; probable DNA-directed DNA polymerase B2 [KO:K02319] [EC:2.7.7.7]
OE_7114F  polB3a; probable DNA-directed DNA polymerase B2 [KO:K02319] [EC:2.7.7.7]
OE_6036F  polB2; DNA-directed DNA polymerase B2 [KO:K02319] [EC:2.7.7.7]
OE_1777F  polB1; DNA-directed DNA polymerase B [KO:K02319] [EC:2.7.7.7]
OE_4293R  polD2; DNA-directed DNA polymerase D large subunit (intein-containing) [KO:K02322] [EC:2.7.7.7]
OE_4390F  polD1; DNA-directed DNA polymerase D exonuclease subunit DP1 [KO:K02323] [EC:2.7.7.7]
OE_2856F  cyaB; adenylate cyclase [KO:K05873] [EC:4.6.1.1]
OE_2579F  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
OE_3425F  adk1; adenylate kinase [KO:K00939] [EC:2.7.4.3]
OE_2506R  adk2; probable adenylate kinase [KO:K18532] [EC:2.7.4.3]
OE_3620R  hit2; histidine triad family protein (homolog to bis(5'-nucleosyl)-tetraphosphatase) [KO:K19710] [EC:2.7.7.53]
OE_5206R  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
KO pathway
ko00230   

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