KEGG   PATHWAY: ko00100Help
Entry
ko00100                     Pathway                                

Name
Steroid biosynthesis
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
Steroid biosynthesis
ko00100

All organismsOrtholog table
Module
M00101  
Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol [PATH:ko00100]
M00102  
Ergocalciferol biosynthesis [PATH:ko00100]
M00103  
Cholecalciferol biosynthesis [PATH:ko00100]
Disease
H00148  
Lysosomal acid lipase deficiency
H00161  
Smith-Lemli-Opitz syndrome
H00496  
Congenital hemidysplasia with ichthyosiform nevus and limb defects (CHILD)
H00617  
Desmosterolosis
H01143  
Vitamin D-dependent rickets
H01194  
X-linked chondrodysplasia punctata
H01281  
Lathosterolosis
H01371  
Hypercalcemia infantile
Drug
D00282  
Clotrimazole (JP16/USP/INN)
D00322  
Fluconazole (JP16/USAN/INN)
D00350  
Itraconazole (JP16/USAN)
D00351  
Ketoconazole (JP16/USP)
D00381  
Tolnaftate (JP16/USP/INN)
D00416  
Miconazole (JP16/USP/INN)
D00578  
Voriconazole (JAN/USAN/INN)
D00880  
Butoconazole nitrate (USP)
D00881  
Econazole nitrate (JAN/USP)
D00882  
Miconazole nitrate (JP16/USP)
D00885  
Oxiconazole nitrate (JAN/USAN)
D00886  
Sulconazole nitrate (JAN/USP)
D00888  
Terconazole (USAN/INN)
D00890  
Tioconazole (JAN/USP/INN)
D01092  
Lanoconazole (JAN/INN)
D01093  
Butenafine hydrochloride (JP16/USAN)
D01429  
Fosfluconazole (JAN/INN)
D01480  
Isoconazole nitrate (JAN)
D01550  
Liranaftate (JAN/INN)
D01620  
Neticonazole hydrochloride (JAN)
D01664  
Omoconazole nitrate (JAN/USAN)
D01720  
Amorolfine hydrochloride (JAN)
D01775  
Bifonazole (JP16/USAN/INN)
D02169  
Croconazole hydrochloride (JP16)
D02219  
Terbinafine hydrochloride (JP16/USP)
D02375  
Terbinafine (USAN/INN)
D02555  
Posaconazole (USAN/INN)
D02556  
Ravuconazole (prop.INN)
D02557  
Chlormidazole (INN)
D02582  
Fenticonazole (INN)
D02583  
Fenticonazole nitrate (USAN)
D02584  
Aliconazole (INN)
D02585  
Vibunazole
D02923  
Amorolfine (USAN/INN)
D03025  
Azalanstat dihydrochloride (USAN)
D03526  
Cisconazole (USAN/INN)
D03936  
Econazole (USAN/INN)
D04624  
Isoconazole (USAN/INN)
D06630  
Pramiconazole (USAN/INN)
D07596  
Butenafine (INN)
D07598  
Butoconazole (INN)
D07676  
Chlormidazole hydrochloride
D07752  
Croconazole (INN)
D08296  
Omoconazole (INN)
D08313  
Oxiconazole (INN)
D08535  
Sulconazole (INN)
Other DBs
BSID: 
GO: 
Orthology
K00801  
farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
K00511  
squalene monooxygenase [EC:1.14.13.132]
K01852  
lanosterol synthase [EC:5.4.99.7]
K05917  
sterol 14-demethylase [EC:1.14.13.70]
K00222  
delta14-sterol reductase [EC:1.3.1.70]
K07750  
methylsterol monooxygenase [EC:1.14.13.72]
K07748  
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170]
K09827  
3-keto steroid reductase [EC:1.1.1.270]
K13373  
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.270 1.1.1.62]
K01824  
cholestenol delta-isomerase [EC:5.3.3.5]
K09828  
delta24-sterol reductase [EC:1.3.1.72]
K00227  
lathosterol oxidase [EC:1.14.21.6]
K00213  
7-dehydrocholesterol reductase [EC:1.3.1.21]
K01052  
lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13]
K12298  
bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
K14674  
TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:2.3.1.51 3.1.1.4 3.1.1.13 3.1.1.3]
K00637  
sterol O-acyltransferase [EC:2.3.1.26]
K07419  
vitamin D 25-hydroxylase [EC:1.14.13.159]
K07438  
25-hydroxyvitamin D3 1alpha-hydroxylase [EC:1.14.13.13]
K07436  
vitamin D3 24-hydroxylase [EC:1.14.13.126]
K00559  
sterol 24-C-methyltransferase [EC:2.1.1.41]
K09829  
C-8 sterol isomerase [EC:5.-.-.-]
K09831  
C-22 sterol desaturase [EC:1.14.14.-]
K00223  
delta24(24(1))-sterol reductase [EC:1.3.1.71]
K01853  
cycloartenol synthase [EC:5.4.99.8]
K14423  
4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase [EC:1.14.13.72]
K08246  
cycloeucalenol cycloisomerase [EC:5.5.1.9]
K08242  
24-methylenesterol C-methyltransferase [EC:2.1.1.143]
K14424  
4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase [EC:1.14.13.72]
K09832  
cytochrome P450, family 710, subfamily A
Compound
C00187  
Cholesterol
C00448  
trans,trans-Farnesyl diphosphate
C00751  
Squalene
C01054  
(S)-2,3-Epoxysqualene
C01164  
7-Dehydrocholesterol
C01189  
Lathosterol
C01561  
Calcidiol
C01673  
Calcitriol
C01694  
Ergosterol
C01724  
Lanosterol
C01753  
beta-Sitosterol
C01789  
Campesterol
C01802  
Desmosterol
C01902  
Cycloartenol
C01943  
Obtusifoliol
C02141  
Cycloeucalenol
C02530  
Cholesterol ester
C03428  
Presqualene diphosphate
C03845  
5alpha-Cholest-8-en-3beta-ol
C04525  
Fecosterol
C05103  
4alpha-Methylzymosterol
C05107  
7-Dehydrodesmosterol
C05108  
14-Demethyllanosterol
C05109  
24,25-Dihydrolanosterol
C05437  
Zymosterol
C05439  
5alpha-Cholesta-7,24-dien-3beta-ol
C05440  
Ergosta-5,7,22,24(28)-tetraen-3beta-ol
C05441  
Vitamin D2
C05442  
Stigmasterol
C05443  
Vitamin D3
C07712  
Secalciferol
C08821  
Isofucosterol
C08830  
24-Methylenecycloartanol
C11455  
4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C11508  
4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
C11522  
24-Methylenelophenol
C11523  
24-Ethylidenelophenol
C15776  
4alpha-Methylfecosterol
C15777  
Episterol
C15778  
5,7,24(28)-Ergostatrienol
C15780  
5-Dehydroepisterol
C15781  
24-Methylenecholesterol
C15782  
delta7-Avenasterol
C15783  
5-Dehydroavenasterol
C15808  
4alpha-Methylzymosterol-4-carboxylate
C15816  
3-Keto-4-methylzymosterol
C15915  
4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
C18231  
Calcitetrol
Reference
  Authors
Koshiba K, Kamiya Y.
  Title
[Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  Journal
Koudansya saientific:199-138 (2002)
Reference
  Authors
Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  Title
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  Journal
Plant Cell 18:1008-22 (2006)
Reference
  Authors
Lange BM, Ghassemian M.
  Title
Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  Journal
Plant Mol Biol 51:925-48 (2003)

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