Tryptophan metabolism

Melatonin biosynthesis, tryptophan => serotonin => melatonin [PATH:ko00380]

Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:ko00380]

Glutaric acidemia

Acatalasia

Brunner syndrome

Delayed sleep phase syndrome

Peters anomaly

Aromatic L-amino acid decarboxylase (AADC) deficiency

Primary congenital glaucoma (PCG)

tryptophan 2,3-dioxygenase [EC:1.13.11.11]

indoleamine 2,3-dioxygenase [EC:1.13.11.52]

arylformamidase [EC:3.5.1.9]

kynurenine formamidase [EC:3.5.1.9]

arylformamidase [EC:3.5.1.9]

kynurenine 3-monooxygenase [EC:1.14.13.9]

kynureninase [EC:3.7.1.3]

anthranilate 3-monooxygenase (FAD) / 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9 1.14.14.8]

FAD reductase [NAD(P)H] [EC:1.5.1.45]

3-hydroxyanthranilate 3,4-dioxygenase [EC:1.13.11.6]

aminocarboxymuconate-semialdehyde decarboxylase [EC:4.1.1.45]

aminomuconate-semialdehyde dehydrogenase [EC:1.2.1.32]

2-aminomuconate deaminase [EC:3.5.99.5]

2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]

glutaryl-CoA dehydrogenase [EC:1.3.8.6]

enoyl-CoA hydratase [EC:4.2.1.17]

3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:5.3.3.8 5.1.2.3 4.2.1.17 1.1.1.35]

3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:5.1.2.3 4.2.1.17 1.1.1.35]

enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.211 4.2.1.17]

enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8 1.1.1.35 4.2.1.17]

enoyl-CoA hydratase [EC:4.2.1.17]

3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]

acetyl-CoA C-acetyltransferase [EC:2.3.1.9]

kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.64 4.4.1.13 2.6.1.7]

kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.39 2.6.1.7]

kynurenine aminotransferase [EC:2.6.1.7]

tryptophanase [EC:4.1.99.1]

aromatic amino acid hydroxylase [EC:1.14.16.-]

tryptophan 5-monooxygenase [EC:1.14.16.4]

aromatic-L-amino-acid decarboxylase [EC:4.1.1.28]

monoamine oxidase [EC:1.4.3.4]

aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]

aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.3 1.2.1.8 1.2.1.31]

aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.3 1.2.1.47]

aldehyde oxidase [EC:1.2.3.1]

acetylserotonin N-methyltransferase [EC:2.1.1.4]

arylalkylamine N-acetyltransferase [EC:2.3.1.87]

unspecific monooxygenase [EC:1.14.14.1]

cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]

cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]

cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]

cytochrome P450 / NADPH-cytochrome P450 reductase [EC:1.6.2.4 1.14.14.1]

methyltransferase [EC:2.1.1.96 2.1.1.49]

cytochrome P450, family 79, subfamily B, polypeptide 2 (tryptophan N-monooxygenase) [EC:1.14.13.125]

cytochrome P450, family 79, subfamily B, polypeptide 3 (tryptophan N-monooxygenase) [EC:1.14.13.125]

indole-3-pyruvate monooxygenase [EC:1.14.13.168]

L-amino-acid oxidase [EC:1.4.3.2]

tryptophan aminotransferase [EC:2.6.1.27]

aromatic amino acid aminotransferase I [EC:2.6.1.5 2.6.1.27 2.6.1.57]

L-tryptophan---pyruvate aminotransferase [EC:2.6.1.99]

indolepyruvate decarboxylase [EC:4.1.1.74]

diamine oxidase [EC:1.4.3.22]

cytochrome P450, family 71, subfamily A, polypeptide 13 (indoleacetaldoxime dehydratase) [EC:4.99.1.6]

indole-3-acetaldehyde oxidase [EC:1.2.3.7]

amidase [EC:3.5.1.4]

nitrilase [EC:3.5.5.1]

nitrile hydratase [EC:4.2.1.84]

tryptophan 2-monooxygenase [EC:1.13.12.3]

cytochrome P450, family 83, subfamily B, polypeptide 1 [EC:1.14.-.-]

ROOTY/SUPERROOT1 [EC:4.4.1.-]

N-hydroxythioamide S-beta-glucosyltransferase [EC:2.4.1.195]

desulfoglucosinolate sulfotransferase A/B/C [EC:2.8.2.-]

myrosinase [EC:3.2.1.147]

catalase [EC:1.11.1.6]

catalase-peroxidase [EC:1.11.1.21]

FAD

Acetyl-CoA

L-Tryptophan

Anthranilate

2-Oxoadipate

L-Kynurenine

Indolepyruvate

Acetoacetyl-CoA

Tryptamine

Indole

Glutaryl-CoA

3-Hydroxyanthranilate

Indole-3-acetaldehyde

5-Hydroxy-L-tryptophan

Serotonin

Crotonoyl-CoA

Indole-3-acetate

Indole-3-ethanol

N-Acetylserotonin

7,8-Dihydroxykynurenate

(S)-3-Hydroxybutanoyl-CoA

7,8-Dihydro-7,8-dihydroxykynurenate

4-(2-Aminophenyl)-2,4-dioxobutanoate

FADH2

Melatonin

4-Hydroxy-2-quinolinecarboxylic acid

2-Aminophenol

Indolelactate

2-Aminophenoxazin-3-one

N-Acetylisatin

2-Aminomuconate

N-Acetylindoxyl

Xanthurenic acid

(Indol-3-yl)acetamide

L-Formylkynurenine

2,3-Dihydroxyindole

Indole-3-acetaldehyde oxime

3-Indoleacetonitrile

3-Hydroxy-L-kynurenine

(Indol-3-yl)glycolaldehyde

gamma-Oxalocrotonate

2-Formylaminobenzaldehyde

Quinolinate

2-Aminomuconate semialdehyde

2-Amino-3-carboxymuconate semialdehyde

5-Hydroxyindoleacetaldehyde

5-Hydroxyindoleacetate

3-Hydroxykynurenamine

4,8-Dihydroxyquinoline

5-Hydroxykynurenamine

4,6-Dihydroxyquinoline

Cinnavalininate

5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate

Formyl-N-acetyl-5-methoxykynurenamine

6-Hydroxymelatonin

3-Methylindolepyruvate

4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate

5-Hydroxyindolepyruvate

Formyl-5-hydroxykynurenamine

5-Hydroxy-N-formylkynurenine

5-Hydroxykynurenine

4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate

Formylanthranilate

5-(2'-Formylethyl)-4,6-dihydroxypicolinate

5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate

5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate

Indoxyl

5-Methoxytryptamine

5-Methoxyindoleacetate

6-Hydroxykynurenate

8-Methoxykynurenate

3-Methoxyanthranilate

5-Hydroxyindoleacetylglycine

3-Methyldioxyindole

2-Formaminobenzoylacetate

Glucobrassicin

N-Methylserotonin

N-Methyltryptamine

Indolylmethylthiohydroximate

Indolylmethyl-desulfoglucosinolate

S-(Indolylmethylthiohydroximoyl)-L-cysteine

N-Hydroxyl-tryptamine