KEGG   PATHWAY: ko00460Help
Entry
ko00460                     Pathway                                

Name
Cyanoamino acid metabolism
Class
Metabolism; Metabolism of other amino acids
BRITE hierarchy
Pathway map
Cyanoamino acid metabolism
ko00460

All organismsOrtholog table
Module
M00369  
Cyanogenic glycoside biosynthesis, tyrosine => dhurrin [PATH:ko00460]
Other DBs
BSID: 
GO: 
Orthology
K13027  
tyrosine N-monooxygenase [EC:1.14.13.41]
K13029  
4-hydroxyphenylacetaldehyde oxime monooxygenase [EC:1.14.13.68]
K13030  
cyanohydrin beta-glucosyltransferase [EC:2.4.1.85]
K01188  
beta-glucosidase [EC:3.2.1.21]
K05349  
beta-glucosidase [EC:3.2.1.21]
K05350  
beta-glucosidase [EC:3.2.1.21]
K08249  
hydroxymandelonitrile lyase [EC:4.1.2.11]
K14984  
isoleucine N-monooxygenase [EC:1.14.13.117]
K13401  
valine N-monooxygenase [EC:1.14.13.118]
K16265  
2-methylbutanal oxime monooxygenase [EC:1.14.13.-]
K16266  
cyanohydrin UDP-glucosyltransferase [EC:2.4.1.-]
K14577  
aliphatic (R)-hydroxynitrile lyase [EC:4.1.2.46]
K13033  
(S)-hydroxynitrile lyase [EC:4.1.2.47]
K12153  
phenylalanine N-monooxygenase [EC:1.14.13.124]
K08248  
mandelonitrile lyase [EC:4.1.2.10]
K13031  
amygdalin beta-glucosidase [EC:3.2.1.117]
K13032  
prunasin beta-glucosidase [EC:3.2.1.118]
K10566  
phenylacetaldoxime dehydratase [EC:4.99.1.7]
K01501  
nitrilase [EC:3.5.5.1]
K13034  
L-3-cyanoalanine synthase/ cysteine synthase [EC:4.4.1.9 2.5.1.47]
K00681  
gamma-glutamyltranspeptidase / glutathione hydrolase [EC:3.4.19.13 2.3.2.2]
K18592  
gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:3.4.19.14 3.4.19.13 2.3.2.2]
K13035  
beta-cyano-L-alanine hydratase/nitrilase [EC:4.2.1.65 3.5.5.4]
K01424  
L-asparaginase [EC:3.5.1.1]
K01914  
aspartate--ammonia ligase [EC:6.3.1.1]
K00600  
glycine hydroxymethyltransferase [EC:2.1.2.1]
K10814  
hydrogen cyanide synthase HcnA [EC:1.4.99.5]
K10815  
hydrogen cyanide synthase HcnB [EC:1.4.99.5]
K10816  
hydrogen cyanide synthase HcnC [EC:1.4.99.5]
K18282  
cyanide dihydratase [EC:3.5.5.-]
K10675  
cyanide hydratase [EC:4.2.1.66]
K01455  
formamidase [EC:3.5.1.49]
Compound
C00014  
Ammonia
C00037  
Glycine
C00049  
L-Aspartate
C00065  
L-Serine
C00079  
L-Phenylalanine
C00082  
L-Tyrosine
C00097  
L-Cysteine
C00152  
L-Asparagine
C00183  
L-Valine
C00302  
Glutamate
C00407  
L-Isoleucine
C00488  
Formamide
C00561  
Mandelonitrile
C00844  
Prunasin
C01326  
Hydrogen cyanide
C01401  
Alanine
C01594  
Linamarin
C02512  
3-Cyano-L-alanine
C02659  
Acetone cyanohydrin
C03004  
N-Hydroxy-L-tyrosine
C03219  
(E)-2-Methylpropanal oxime
C03742  
(S)-4-Hydroxymandelonitrile
C04353  
(Z)-4-Hydroxyphenylacetaldehyde oxime
C05143  
Dhurrin
C05670  
3-Aminopropiononitrile
C05711  
gamma-Glutamyl-beta-cyanoalanine
C05714  
alpha-Aminopropiononitrile
C05715  
gamma-Amino-gamma-cyanobutanoate
C06114  
gamma-Glutamyl-beta-aminopropiononitrile
C08325  
Amygdalin
C08334  
Lotaustralin
C15503  
N,N-Dihydroxy-L-tyrosine
C16074  
Phenylacetonitrile
C16075  
(Z)-Phenylacetaldehyde oxime
C18796  
(2R)-2-Hydroxy-2-methylbutanenitrile
C19491  
(E)-2-Methylbutanal oxime
C19712  
N-Hydroxy-L-phenylalanine
C19714  
(E)-Phenylacetaldoxime
C19715  
N,N-Dihydroxy-L-phenylalanine
C20310  
N-Hydroxy-L-isoleucine
C20311  
N,N-Dihydroxy-L-isoleucine
C20312  
(Z)-2-Methylbutanal oxime
C20313  
N-Hydroxy-L-valine
C20314  
N,N-Dihydroxy-L-valine
C20315  
(Z)-2-Methylpropanal oxime
Reference
  Authors
Maruyama A, Saito K, Ishizawa K
  Title
Beta-cyanoalanine synthase and cysteine synthase from potato: molecular cloning,  biochemical characterization, and spatial and hormonal regulation.
  Journal
Plant Mol Biol 46:749-60 (2001)
Reference
  Authors
Andersen MD, Busk PK, Svendsen I, Moller BL
  Title
Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin. Cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated recombinant enzymes.
  Journal
J Biol Chem 275:1966-75 (2000)
Reference
  Authors
Andrea H, Meinhard H, Herfried G.
  Title
Hydroxynitrile lyases: Functions and properties
  Journal
Physiologia Plantarum 98(4):891-898 (2006)

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