KEGG   PATHWAY: ko00621Help
Entry
ko00621                     Pathway                                
Name
Dioxin degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
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Pathway map
Dioxin degradation
ko00621

All organismsOrtholog table
Module
M00543  
Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate [PATH:ko00621]
M00544  
Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate [PATH:ko00621]
Other DBs
BSID: 
UMBBD: 
Orthology
K14599  
dibenzofuran dioxygenase alpha subunit [EC:1.14.12.-]
K14600  
dibenzofuran dioxygenase beta subunit [EC:1.14.12.-]
K15749  
2,2',3-trihydroxybiphenyl dioxygenase [EC:1.13.11.-]
K10222  
2,6-dioxo-6-phenylhexa-3-enoate hydrolase [EC:3.7.1.8]
K01821  
4-oxalocrotonate tautomerase [EC:5.3.2.-]
K00480  
salicylate hydroxylase [EC:1.14.13.1]
K01617  
4-oxalocrotonate decarboxylase [EC:4.1.1.77]
K02554  
2-keto-4-pentenoate hydratase [EC:4.2.1.80]
K01666  
4-hydroxy 2-oxovalerate aldolase [EC:4.1.3.39]
K00132  
acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10]
K04072  
acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.1.1.1 1.2.1.10]
K04073  
acetaldehyde dehydrogenase [EC:1.2.1.10]
K04021  
aldehyde dehydrogenase
K08689  
biphenyl 2,3-dioxygenase subunit alpha [EC:1.14.12.18]
K15750  
biphenyl 2,3-dioxygenase subunit beta [EC:1.14.12.18]
K05710  
dioxygenase ferredoxin subunit
K00529  
ferredoxin--NAD+ reductase [EC:1.18.1.3]
K08690  
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [EC:1.3.1.56]
K00462  
biphenyl-2,3-diol 1,2-dioxygenase [EC:1.13.11.39]
K15751  
carbazole 1,9a-dioxygenase, terminal dioxygenase component [EC:1.14.12.22]
K15752  
carbazole 1,9a-dioxygenase, ferredoxin component
K15753  
carbazole 1,9a-dioxygenase, ferredoxin reductase component
K15754  
2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, small subunit [EC:1.13.11.-]
K15755  
2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, large subunit [EC:1.13.11.-]
K15756  
2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase [EC:3.7.1.-]
Compound
C00022  
Pyruvate
C00024  
Acetyl-CoA
C00084  
Acetaldehyde
C00090  
Catechol
C00108  
Anthranilate
C00180  
Benzoate
C00596  
2-Hydroxy-2,4-pentadienoate
C00805  
Salicylate
C01273  
2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
C02370  
4-Chlorobenzoate
C02501  
2-Hydroxymuconate
C02526  
Biphenyl-2,3-diol
C03453  
gamma-Oxalocrotonate
C03569  
2,2',3-Trihydroxybiphenyl
C03589  
4-Hydroxy-2-oxopentanoate
C06584  
4-Chlorobiphenyl
C06585  
cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl
C06586  
2,3-Dihydroxy-4'-chlorobiphenyl
C06587  
2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate
C06588  
Biphenyl
C06589  
cis-2,3-Dihydro-2,3-dihydroxybiphenyl
C07557  
2,3,7,8-Tetrachlorodibenzodioxin
C07729  
Dibenzofuran
C07731  
2-Hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate
C07732  
Dibenzo-p-dioxin
C07733  
2,2',3-Trihydroxydiphenylether
C07734  
2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate
C08060  
Carbazole
C08061  
2'-Aminobiphenyl-2,3-diol
C08062  
2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate
C11057  
3,4,3',4'-Tetrachlorobiphenyl
C14573  
3,3',4,4',5-Pentachlorobiphenyl
C18099  
1,2,3,7,8-Pentachlorodibenzodioxin
C18100  
1,2,3,4,7,8-Hexachlorodibenzodioxin
C18101  
1,2,3,6,7,8-Hexachlorodibenzodioxin
C18102  
1,2,3,7,8,9-Hexachlorodibenzodioxin
C18103  
1,2,3,4,6,7,8-Heptachlorodibenzodioxin
C18104  
2,3,7,8-Tetrachlorodibenzofuran
C18105  
1,2,3,7,8-Pentachlorodibenzofuran
C18106  
2,3,4,7,8-Pentachlorodibenzofuran
C18107  
1,2,3,4,7,8-Hexachlorodibenzofuran
C18108  
1,2,3,7,8,9-Hexachlorodibenzofuran
C18109  
1,2,3,6,7,8-Hexachlorodibenzofuran
C18110  
2,3,4,6,7,8-Hexachlorodibenzofuran
C18111  
1,2,3,4,6,7,8-Heptachlorodibenzofuran
C18112  
1,2,3,4,7,8,9-Heptachlorodibenzofuran
C18113  
1,2,3,4,6,7,8,9-Octachlorodibenzofuran
C18114  
3,4,4',5-Tetrachlorobiphenyl
C18115  
3,4,5,3',4',5'-Hexachlorobiphenyl
C18116  
2,3,4,3',4'-Pentachlorobiphenyl
C18117  
2,3,4,4',5-Pentachlorobiphenyl
C18118  
2,3',4,4',5-Pentachlorobiphenyl
C18119  
2,3',4,4',5'-Pentachlorobiphenyl
C18120  
2,3,3',4,4',5-Hexachlorobiphenyl
C18121  
2,3,3',4,4',5'-Hexachlorobiphenyl
C18122  
2,3',4,4',5,5'-Hexachlorobiphenyl
C18123  
2,3,3',4,4',5,5'-Heptachlorobiphenyl
C18180  
1,2,3,4,6,7,8,9-Octachlorodibenzo-p-dioxin
Reference
  Authors
Nojiri H, Omori T.
  Title
Molecular bases of aerobic bacterial degradation of dioxins: involvement of angular dioxygenation.
  Journal
Biosci Biotechnol Biochem 66:2001-16 (2002)
Reference
  Authors
Jin S, Zhu T, Xu X, Xu Y.
  Title
Biodegradation of dibenzofuran by Janibacter terrae strain XJ-1.
  Journal
Curr Microbiol 53:30-6 (2006)
Reference
  Authors
Nojiri H, Habe H, Omori T.
  Title
Bacterial degradation of aromatic compounds via angular dioxygenation.
  Journal
J Gen Appl Microbiol 47:279-305 (2001)
Reference
  Authors
Kasuga K, Habe H, Chung JS, Yoshida T, Nojiri H, Yamane H, Omori T.
  Title
Isolation and characterization of the genes encoding a novel oxygenase component of angular dioxygenase from the gram-positive dibenzofuran-degrader Terrabacter sp. strain DBF63.
  Journal
Biochem Biophys Res Commun 283:195-204 (2001)
Reference
  Authors
Vezina J, Barriault D, Sylvestre M
  Title
Family shuffling of soil DNA to change the regiospecificity of Burkholderia xenovorans LB400 biphenyl dioxygenase.
  Journal
J Bacteriol 189:779-88 (2007)
Reference
  Authors
Ouchiyama N, Miyachi S, Omori T
  Title
Cloning and nucleotide sequence of carbazole catabolic genes from Pseudomonas stutzeri strain OM1, isolated from activated sludge.
  Journal
J Gen Appl Microbiol 44:57-63 (1998)
Reference
PMID:9244273
  Authors
Sato SI, Ouchiyama N, Kimura T, Nojiri H, Yamane H, Omori T
  Title
Cloning of genes involved in carbazole degradation of Pseudomonas sp. strain CA10: nucleotide sequences of genes and characterization of meta-cleavage enzymes and hydrolase.
  Journal
J Bacteriol 179:4841-9 (1997)
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