KEGG   PATHWAY: ko00626Help
Entry
ko00626                     Pathway                                
Name
Naphthalene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
BRITE hierarchy
Pathway map
Naphthalene degradation
ko00626

All organismsOrtholog table
Module
M00534  
Naphthalene degradataion, naphthalene => salicylate [PATH:ko00626]
Other DBs
BSID: 
UMBBD: 
Orthology
K14579  
naphthalene 1,2-dioxygenase subunit alpha [EC:1.14.12.12]
K14580  
naphthalene 1,2-dioxygenase subunit beta [EC:1.14.12.12]
K14578  
naphthalene 1,2-dioxygenase system ferredoxin subunit
K14581  
naphthalene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component [EC:1.18.1.3]
K14582  
cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase [EC:1.3.1.60 1.3.1.29]
K14583  
1,2-dihydroxynaphthalene dioxygenase [EC:1.13.11.56]
K14584  
2-hydroxychromene-2-carboxylate isomerase [EC:5.99.1.4]
K14585  
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase [EC:4.1.2.45]
K00152  
salicylaldehyde dehydrogenase [EC:1.2.1.65]
K00480  
salicylate hydroxylase [EC:1.14.13.1]
K00492  
[EC:1.14.13.-]
K05915  
[EC:1.13.-.-]
K01726  
[EC:4.2.1.-]
K00155  
[EC:1.2.1.-]
K13953  
alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
K13954  
alcohol dehydrogenase [EC:1.1.1.1]
K00001  
alcohol dehydrogenase [EC:1.1.1.1]
K00121  
S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.1 1.1.1.284]
K04072  
acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.1.1.1 1.2.1.10]
K03384  
[EC:1.14.12.-]
K01670  
naphthyl-2-methylsuccinate synthase alpha subunit [EC:4.1.99.-]
K15567  
naphthyl-2-methylsuccinate synthase beta subunit [EC:4.1.99.-]
K15568  
naphthyl-2-methylsuccinate synthase gamma subunit [EC:4.1.99.-]
K15569  
naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15570  
naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15571  
naphthyl-2-methylsuccinyl-CoA dehydrogenase [EC:1.3.99.-]
K15572  
naphthyl-2-hydroxymethylsuccinyl-CoA hydratase [EC:4.2.1.-]
K15573  
naphthyl-2-hydroxymethylsuccinyl-CoA dehydrogenase [EC:1.1.-.-]
K15574  
naphthyl-2-oxomethyl-succinyl-CoA thiolase subunit [EC:2.3.1.-]
K15575  
naphthyl-2-oxomethyl-succinyl-CoA thiolase subunit [EC:2.3.1.-]
K01041  
[EC:2.8.3.-]
K14586  
2-naphthoate monooxygenase
Compound
C00090  
Catechol
C00091  
Succinyl-CoA
C00628  
2,5-Dihydroxybenzoate
C00805  
Salicylate
C00829  
Naphthalene
C02909  
(2-Naphthyl)methanol
C02923  
2,3-Dihydroxytoluene
C03012  
Naphthalene-1,2-diol
C03203  
1-Hydroxy-2-naphthoate
C04314  
cis-1,2-Dihydronaphthalene-1,2-diol
C06202  
Salicylaldehyde
C06203  
trans-o-Hydroxybenzylidenepyruvate
C06204  
2-Hydroxychromene-2-carboxylate
C06730  
4-Methylcatechol
C14082  
1-Methylnaphthalene
C14083  
cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene
C14084  
1,2-Dihydroxy-8-methylnaphthalene
C14085  
2-Hydroxy-8-methylchromene-2-carboxylate
C14086  
2-Hydroxy-3-methylbenzalpyruvate
C14087  
3-Methylsalicylaldehyde
C14088  
3-Methylsalicylate
C14089  
1-Hydroxymethylnaphthalene
C14090  
1-Naphthaldehyde
C14091  
1-Naphthoic acid
C14092  
cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene
C14093  
1,2-Dihydroxy-8-carboxynaphthalene
C14094  
2-Carboxy-2-hydroxy-8-carboxychromene
C14095  
2-Hydroxy-3-carboxybenzalpyruvate
C14096  
3-Formylsalicylic acid
C14097  
2-Hydroxyisophthalic acid
C14098  
2-Methylnaphthalene
C14099  
2-Naphthaldehyde
C14100  
4-Formylsalicylic acid
C14101  
2-Naphthoic acid
C14102  
cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene
C14103  
4-Methylsalicylate
C14104  
cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene
C14105  
1,2-Dihydroxy-7-hydroxymethylnaphthalene
C14106  
2-Hydroxy-7-hydroxymethylchromene-2-carboxylate
C14107  
2-Hydroxy-4-hydroxymethylbenzalpyruvate
C14108  
4-Hydroxymethylsalicylaldehyde
C14109  
4-Hydroxymethylsalicylate
C14110  
4-Hydroxymethylcatechol
C14111  
5,6,7,8-Tetrahydro-2-naphthoic acid
C14112  
cis-2-Carboxycyclohexyl-acetic acid
C14113  
Decahydro-2-naphthoic acid
C14114  
Tetralin
C14115  
2-Naphtylmethylsuccinic acid
C14116  
Naphthyl-2-methyl-succinyl-CoA
C14117  
Naphthyl-2-methylene-succinyl-CoA
C14118  
Naphthyl-2-hydroxymethyl-succinyl CoA
C14119  
Naphthyl-2-oxomethyl-succinyl-CoA
C14120  
2-Naphthoyl-CoA
C16193  
1,6-Naphthalenedisulfonic acid
C16194  
2,6-Naphthalenedisulfonic acid
C16196  
1,2-Dihydroxynaphthalene-6-sulfonate
C16198  
(Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate
C16199  
5-Sulfosalicylate
C16201  
1-Naphthalenesulfonic acid
C16202  
2-Naphthalenesulfonic acid
Reference
  Authors
Kim SJ, Kweon O, Freeman JP, Jones RC, Adjei MD, Jhoo JW, Edmondson RD, Cerniglia CE.
  Title
Molecular cloning and expression of genes encoding a novel dioxygenase involved in low- and high-molecular-weight polycyclic aromatic hydrocarbon degradation in Mycobacterium vanbaalenii PYR-1.
  Journal
Appl Environ Microbiol 72:1045-54 (2006)
Reference
PMID:8226631
  Authors
Denome SA, Stanley DC, Olson ES, Young KD
  Title
Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway.
  Journal
J Bacteriol 175:6890-901 (1993)
Reference
PMID:1447127
  Authors
Eaton RW, Chapman PJ
  Title
Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions.
  Journal
J Bacteriol 174:7542-54 (1992)
Reference
PMID:8981987
  Authors
Morawski B, Eaton RW, Rossiter JT, Guoping S, Griengl H, Ribbons DW
  Title
2-Naphthoate catabolic pathway in Burkholderia strain JT 1500.
  Journal
J Bacteriol 179:115-21 (1997)
Reference
  Authors
Safinowski M, Meckenstock RU
  Title
Enzymatic reactions in anaerobic 2-methylnaphthalene degradation by the sulphate-reducing enrichment culture N 47.
  Journal
FEMS Microbiol Lett 240:99-104 (2004)
Reference
  Authors
Annweiler E, Materna A, Safinowski M, Kappler A, Richnow HH, Michaelis W, Meckenstock RU
  Title
Anaerobic degradation of 2-methylnaphthalene by a sulfate-reducing enrichment culture.
  Journal
Appl Environ Microbiol 66:5329-33 (2000)
Reference
  Authors
Annweiler E, Michaelis W, Meckenstock RU
  Title
Identical ring cleavage products during anaerobic degradation of naphthalene, 2-methylnaphthalene, and tetralin indicate a new metabolic pathway.
  Journal
Appl Environ Microbiol 68:852-8 (2002)
Reference
  Authors
Aitken CM, Jones DM, Larter SR
  Title
Anaerobic hydrocarbon biodegradation in deep subsurface oil reservoirs.
  Journal
Nature 431:291-4 (2004)
Reference
  Authors
Selesi D, Jehmlich N, von Bergen M, Schmidt F, Rattei T, Tischler P, Lueders T, Meckenstock RU
  Title
Combined genomic and proteomic approaches identify gene clusters involved in anaerobic 2-methylnaphthalene degradation in the sulfate-reducing enrichment culture N47.
  Journal
J Bacteriol 192:295-306 (2010)
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