KEGG   PATHWAY: ko00650Help
Entry
ko00650                     Pathway                                

Name
Butanoate metabolism
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
Butanoate metabolism
ko00650

All organismsOrtholog table
Disease
H00179  
3-Hydroxy-3-methylglutaryl-CoA lyase deficiency
H00835  
Succinic semialdehyde dehydrogenase (SSADH) deficiency
H01097  
Cerebral palsy
H01121  
Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency
H01123  
HMG-CoA synthase (HMGCS) deficiency
H01280  
L-2-hydroxyglutaric aciduria (L2HGA)
H01364  
3-Hydroxyacyl-CoA dehydrogenase deficiency
Orthology
K00626  
acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00074  
3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K00022  
3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K01825  
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:5.3.3.8 5.1.2.3 4.2.1.17 1.1.1.35]
K01782  
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:5.1.2.3 4.2.1.17 1.1.1.35]
K01692  
enoyl-CoA hydratase [EC:4.2.1.17]
K01715  
enoyl-CoA hydratase [EC:4.2.1.17]
K07515  
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.211 4.2.1.17]
K07514  
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8 1.1.1.35 4.2.1.17]
K07511  
enoyl-CoA hydratase [EC:4.2.1.17]
K00248  
butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00209  
enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.44 1.3.1.-]
K17829  
crotonyl-CoA reductase [EC:1.3.1.86]
K01034  
acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.9 2.8.3.8]
K01035  
acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.9 2.8.3.8]
K01896  
medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K00929  
butyrate kinase [EC:2.7.2.7]
K00634  
phosphate butyryltransferase [EC:2.3.1.19]
K00132  
acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10]
K04072  
acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.1.1.1 1.2.1.10]
K04073  
acetaldehyde dehydrogenase [EC:1.2.1.10]
K18366  
acetaldehyde/propanal dehydrogenase [EC:1.2.1.87 1.2.1.10]
K00100  
[EC:1.1.1.-]
K17865  
3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
K03821  
polyhydroxyalkanoate synthase [EC:2.3.1.-]
K05973  
poly(3-hydroxybutyrate) depolymerase [EC:3.1.1.75]
K00023  
acetoacetyl-CoA reductase [EC:1.1.1.36]
K01615  
glutaconyl-CoA decarboxylase [EC:4.1.1.70]
K01726  
[EC:4.2.1.-]
K01039  
glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
K01040  
glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
K00109  
2-hydroxyglutarate dehydrogenase [EC:1.1.99.2]
K07246  
tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.83 4.1.1.73 1.1.1.93]
K01799  
maleate isomerase [EC:5.2.1.1]
K00239  
succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240  
succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241  
succinate dehydrogenase cytochrome b556 subunit
K00242  
succinate dehydrogenase membrane anchor subunit
K01580  
glutamate decarboxylase [EC:4.1.1.15]
K00823  
4-aminobutyrate aminotransferase [EC:2.6.1.19]
K14268  
5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.19 2.6.1.48]
K07250  
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.22 2.6.1.19]
K13524  
4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.22 2.6.1.19]
K16871  
4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96]
K00135  
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.20 1.2.1.79 1.2.1.16]
K00139  
succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
K17761  
succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24]
K08324  
succinate-semialdehyde dehydrogenase [EC:1.2.1.24 1.2.1.16]
K18118  
succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
K18119  
succinate-semialdehyde dehydrogenase [EC:1.2.1.76]
K18120  
4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
K00043  
4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
K08318  
4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
K18121  
glyoxylate/succinic semialdehyde reductase [EC:1.1.1.- 1.1.1.79]
K18122  
4-hydroxybutyrate CoA-transferase [EC:2.8.3.-]
K14534  
4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:5.3.3.3 4.2.1.120]
K00656  
formate C-acetyltransferase [EC:2.3.1.54]
K00169  
pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
K00170  
pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
K00172  
pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
K00171  
pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
K01641  
hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K01640  
hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
K01027  
3-oxoacid CoA-transferase [EC:2.8.3.5]
K01028  
3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
K01029  
3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
K01907  
acetoacetyl-CoA synthetase [EC:6.2.1.16]
K00019  
3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
K07518  
hydroxybutyrate-dimer hydrolase [EC:3.1.1.22]
K01652  
acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  
acetolactate synthase I/III small subunit [EC:2.2.1.6]
K11258  
acetolactate synthase II small subunit [EC:2.2.1.6]
K01575  
acetolactate decarboxylase [EC:4.1.1.5]
K00004  
(R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.303 1.1.1.- 1.1.1.4]
K03366  
meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.304 1.1.1.76 1.1.1.-]
K18009  
meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.304 1.1.1.76 1.1.1.-]
Compound
C00022  
Pyruvate
C00024  
Acetyl-CoA
C00025  
L-Glutamate
C00026  
2-Oxoglutarate
C00042  
Succinate
C00091  
Succinyl-CoA
C00122  
Fumarate
C00136  
Butanoyl-CoA
C00164  
Acetoacetate
C00232  
Succinate semialdehyde
C00246  
Butanoic acid
C00332  
Acetoacetyl-CoA
C00334  
4-Aminobutanoate
C00356  
(S)-3-Hydroxy-3-methylglutaryl-CoA
C00497  
(R)-Malate
C00741  
Diacetyl
C00810  
(R)-Acetoin
C00877  
Crotonoyl-CoA
C00989  
4-Hydroxybutanoic acid
C01089  
(R)-3-Hydroxybutanoate
C01144  
(S)-3-Hydroxybutanoyl-CoA
C01384  
Maleic acid
C01412  
Butanal
C01769  
(S)-Acetoin
C02331  
Vinylacetyl-CoA
C02411  
Glutaconyl-1-CoA
C02527  
Butanoylphosphate
C02630  
2-Hydroxyglutarate
C03044  
(R,R)-Butane-2,3-diol
C03046  
(S,S)-Butane-2,3-diol
C03058  
2-Hydroxyglutaryl-CoA
C03561  
(R)-3-Hydroxybutanoyl-CoA
C04546  
(R)-3-((R)-3-Hydroxybutanoyloxy)butanoate
C06010  
(S)-2-Acetolactate
C06142  
1-Butanol
C06143  
Poly-beta-hydroxybutyrate
C06144  
3-Butynoate
C06145  
3-Butyn-1-al
C06146  
3-Butyn-1-ol
C11062  
4-Hydroxybutyryl-CoA
C20657  
meso-2,3-Butanediol

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