KEGG PATHWAY: ko00904

PATHWAY: ko00904

Entry

ko00904 Pathway

Name

Diterpenoid biosynthesis

Class

Metabolism; Metabolism of terpenoids and polyketides

Pathway map

ko00904

Diterpenoid biosynthesis

Other DBs

BSID:

412

GO:

0016102

Orthology

K04120	ent-copalyl diphosphate synthase [EC:5.5.1.13]
K04121	ent-kaurene synthase [EC:4.2.3.19]
K04122	ent-kaurene oxidase [EC:1.14.13.78]
K04123	ent-kaurenoic acid hydroxylase [EC:1.14.13.79]
K05282	gibberellin 20-oxidase [EC:1.14.11.12]
K04124	gibberellin 3-beta-dioxygenase [EC:1.14.11.15]
K04125	gibberellin 2-oxidase [EC:1.14.11.13]
K12917	cytochrome P450 monooxygenase 1
K12918	cytochrome P450 monooxygenase 2
K12919	cytochrome P450 monooxygenase 3
K12920	GA4 desaturase
K16082	ent-isokaurene synthase [EC:4.2.3.103]
K16083	cytochrome P450, family 71, subfamily Z, polypeptide 6 (ent-isokaurene C2-hydroxylase) [EC:1.14.13.143]
K14036	ent-cassa-12,15-diene synthase [EC:4.2.3.28]
K16084	cytochrome P450, family 76, subfamily M, polypeptide 7 (ent-cassa-12,15-diene 11-hydroxylase) [EC:1.14.13.145]
K14037	ent-sandaracopimaradiene synthase [EC:4.2.3.29]
K14038	ent-pimara-8(14),15-diene synthase [EC:4.2.3.30]
K12921	taxadiene synthase [EC:4.2.3.17]
K14039	taxadiene 5alpha-hydroxylase [EC:1.14.99.37]
K12922	taxane 13-alpha-hydroxylase [EC:1.14.13.77]
K12923	taxadien-5-alpha-ol O-acetyltransferase [EC:2.3.1.162]
K12924	taxane 10-beta-hydroxylase [EC:1.14.13.76]
K12925	2-alpha-hydroxytaxane 2-O-benzoyltransferase [EC:2.3.1.166]
K12926	10-deacetylbaccatin III 10-O-acetyltransferase [EC:2.3.1.167]
K12927	abietadiene synthase/copalyl diphosphate synthase [EC:5.5.1.12 4.2.3.18]
K14040	cytochrome P450, family 720, subfamily B, polypeptide 1 (abietadienol/abietadienal oxidase) [EC:1.14.13.109]
K14041	levopimaradiene synthase /copalyl diphosphate synthase [EC:5.5.1.12 4.2.3.32]
K14042	isopimara-7,15-diene synthase /copalyl diphosphate synthase [EC:5.5.1.12 4.2.3.44]
K14043	syn-copalyl-diphosphate synthase [EC:5.5.1.14]
K12928	aphidicolan-16beta-ol synthase/syn-copalyl-diphosphate synthase [EC:5.5.1.14 4.2.3.42]
K14044	stemar-13-ene synthase [EC:4.2.3.33]
K14045	stemod-13(17)-ene synthase [EC:4.2.3.34]
K14046	syn-pimara-7,15-diene synthase [EC:4.2.3.35]
K16085	cytochrome P450, family 99, subfamily A, polypeptide 3 (9beta-pimara-7,15-diene oxidase) [EC:1.14.13.144]
K13070	momilactone-A synthase [EC:1.1.1.295]
K12929	casbene synthase [EC:4.2.3.8]
K16086	(13E)-labda-7,13-dien-15-ol synthase [EC:3.1.7.10]
K14047	fusicocca-2,10(14)-diene synthase [EC:4.2.3.43]

Compound

C00353	Geranylgeranyl diphosphate
C00859	Gibberellin A1
C01414	Casbene
C01699	Gibberellin A3
C02034	Gibberellin A19
C02035	Gibberellin A20
C03579	Gibberellin A8
C06087	Abietate
C06088	Aphidicolin
C06089	ent-Copalyl diphosphate
C06090	ent-Kaurene
C06091	Aconitine
C06092	Veatchine
C06093	Gibberellin A12 aldehyde
C06094	Gibberellin A53
C06095	Gibberellin A44 diacid
C06096	Gibberellin A29
C07394	Paclitaxel
C09094	Geranylgeraniol
C09118	Isopimaric acid
C09183	Sclareol
C11700	10-Deacetylbaccatin III
C11853	Gibberellin A14 aldehyde
C11854	Gibberellin A51-catabolite
C11855	Gibberellin A29-catabolite
C11857	Gibberellin A12
C11858	Gibberellin A14
C11859	Gibberellin A37 open lactone
C11860	Gibberellin A15 open lactone
C11861	Gibberellin A24
C11862	Gibberellin A36
C11863	Gibberellin A9
C11864	Gibberellin A4
C11865	Gibberellin A51
C11866	2,3-Dehydro-gibberellin A9
C11867	Gibberellin A7
C11868	Gibberellin A34
C11869	Gibberellin A34-catabolite
C11870	Gibberellin A8-catabolite
C11871	Gibberellin A5
C11872	Kaur-16-en-18-ol
C11873	Kaur-16-en-18-al
C11874	Kaur-16-en-18-oic acid
C11875	ent-7alpha-Hydroxykaur-16-en-19-oic acid
C11876	6beta,7beta-Dihydroxykaurenoic acid
C11877	(+)-Sandaracopimaradiene
C11878	(-)-Abietadiene
C11879	Levopimaradiene
C11880	Neoabietadiene
C11881	Palustradiene
C11882	Abietinol
C11883	Levopimarinol
C11884	Neoabietinol
C11885	Neoabietal
C11886	Levopimarinal
C11887	Abietal
C11888	Levopimaric acid
C11889	Neoabietic acid
C11890	Aphidicolan-16beta-ol
C11893	Cembrene
C11894	Taxa-4(5),11(12)-diene
C11895	Taxa-4(20),11(12)-dien-5alpha-ol
C11896	Taxa-4(20),11(12)-dien-5alpha-yl acetate
C11897	Taxa-4(20),11(12)-dien-5alpha,13alpha-diol
C11898	Taxa-4(20),11(12)-dien-5alpha-acetoxy-10beta-ol
C11899	10-Deacetyl-2-debenzoylbaccatin III
C11900	Baccatin III
C11901	Copalyl diphosphate
C11902	9alpha-Copalyl diphosphate
C11905	Gibberellin A53 aldehyde
C12077	Palustric acid
C13273	Plaunotol
C16523	3'-N-Debenzoyl-2'-deoxytaxol
C16524	3'-N-Debenzoyltaxol
C18015	Momilactone A
C18016	3beta-Hydroxy-9beta-pimara-7,15-diene-19,6beta-olide
C18211	Isopimara-7,15-diene
C18219	Palustradienol
C18220	Palustradienal
C18221	Isopimaradienol
C18222	Isopimaradienal
C18223	Stemar-13-ene
C18224	Stemod-13(17)-ene
C18225	9beta-Pimara-7,15-diene
C18226	ent-Cassa-12,15-diene
C18228	ent-Pimara-8(14),15-diene
C18229	Fusicocca-2,10(14)-diene
C20145	ent-Isokaurene
C20146	ent-2alpha-Hydroxyisokaurene
C20149	9beta-Pimara-7,15-dien-19-oate
C20150	ent-11beta-Hydroxycassa-12,15-diene
C20151	10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate
C20158	(13E)-Labda-7,13-dien-15-ol
C20208	syn-Stemoden-19-oate
C20270	Copal-8-ol diphosphate

Reference

PMID:16137660

Authors

Long RM, Croteau R.

Title

Preliminary assessment of the C13-side chain 2'-hydroxylase involved in taxol biosynthesis.

Journal

Biochem Biophys Res Commun 338:410-7 (2005)

Reference

PMID:12089320

Authors

Walker K, Long R, Croteau R.

Title

The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus.

Journal

Proc Natl Acad Sci U S A 99:9166-71 (2002)

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Ontology (2)   
   KEGG BRITE (1)   
   GO (1)   
Pathway (3)   
   KEGG PATHWAY (2)   
   BioSystems (1)   
Chemical substance (95)   
   KEGG COMPOUND (95)   
Chemical reaction (35)   
   KEGG ENZYME (35)   
Gene (38)   
   KEGG ORTHOLOGY (38)   
Literature (2)   
   PubMed (2)   
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