KEGG   PATHWAY: lma04140Help
Entry
lma04140                    Pathway                                

Name
Regulation of autophagy - Leishmania major
Class
Cellular Processes; Transport and catabolism
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Pathway map
Regulation of autophagy
lma04140

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BSID: 
GO: 
Organism
Leishmania major [GN:lma]
Gene
putative serine/threonine protein kinase; K07198 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11] [KO:K07198] [EC:2.7.11.11]
putative protein kinase; K08333 phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] [KO:K08333] [EC:2.7.11.1]
putative phosphatidylinositol kinase; K00914 phosphatidylinositol 3-kinase [EC:2.7.1.137] [KO:K00914] [EC:2.7.1.137]
putative phosphatidylinositol 3-kinase; K00914 phosphatidylinositol 3-kinase [EC:2.7.1.137] [KO:K00914] [EC:2.7.1.137]
putative phosphatidylinositol 3-kinase; K00914 phosphatidylinositol 3-kinase [EC:2.7.1.137] [KO:K00914] [EC:2.7.1.137]
putative ubiquitin activating E1 enzyme; K08337 ubiquitin-like modifier-activating enzyme ATG7 [KO:K08337]
ATG8; putative ATG8/AUT7/APG8/PAZ2 [KO:K08341]
ATG4.1; putative AUT2/APG4/ATG4 cysteine peptidase [KO:K08342] [EC:3.4.22.-]
Compound
C00350  
Phosphatidylethanolamine
C00913  
3-Methyladenine
C01194  
1-Phosphatidyl-D-myo-inositol
C04549  
1-Phosphatidyl-1D-myo-inositol 3-phosphate
C15181  
Wortmannin
Reference
  Authors
Meijer AJ, Codogno P.
  Title
Regulation and role of autophagy in mammalian cells.
  Journal
Int J Biochem Cell Biol 36:2445-62 (2004)
Reference
  Authors
Deretic V.
  Title
Autophagy in innate and adaptive immunity.
  Journal
Trends Immunol 26:523-8 (2005)
Reference
  Authors
Thompson AR, Vierstra RD.
  Title
Autophagic recycling: lessons from yeast help define the process in plants.
  Journal
Curr Opin Plant Biol 8:165-73 (2005)
Reference
  Authors
Levine B, Yuan J.
  Title
Autophagy in cell death: an innocent convict?
  Journal
J Clin Invest 115:2679-88 (2005)
Reference
  Authors
Tanida I, Ueno T, Kominami E.
  Title
LC3 conjugation system in mammalian autophagy.
  Journal
Int J Biochem Cell Biol 36:2503-18 (2004)
Reference
  Authors
Lum JJ, DeBerardinis RJ, Thompson CB.
  Title
Autophagy in metazoans: cell survival in the land of plenty.
  Journal
Nat Rev Mol Cell Biol 6:439-48 (2005)
Reference
  Authors
Reggiori F, Klionsky DJ.
  Title
Autophagosomes: biogenesis from scratch?
  Journal
Curr Opin Cell Biol 17:415-22 (2005)
Reference
  Authors
Klionsky DJ, Emr SD.
  Title
Autophagy as a regulated pathway of cellular degradation.
  Journal
Science 290:1717-21 (2000)
Reference
  Authors
Bechet D, Tassa A, Taillandier D, Combaret L, Attaix D.
  Title
Lysosomal proteolysis in skeletal muscle.
  Journal
Int J Biochem Cell Biol 37:2098-114 (2005)
KO pathway
 

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