| Entry |
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| Name |
Arginine and proline metabolism
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| Class |
Metabolism; Amino acid metabolism
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| Pathway map |
| Arginine and proline metabolism |
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| Module |
| Proline biosynthesis, glutamate => proline [PATH: map00330] | | Ornithine biosynthesis, glutamate => ornithine [PATH: map00330] | | | | | | Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH: map00330] | | Polyamine biosynthesis, arginine => ornithine => putrescine [PATH: map00330] | | GABA biosynthesis, eukaryotes, putrescine => GABA [PATH: map00330] | | GABA biosynthesis, prokaryotes, putrescine => GABA [PATH: map00330] |
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| Disease |
| Carbamoyl phosphate synthetase I deficiency | | Citrullinemia (CTLN) | | Hyperargininemia | | Ornithine transcarbamylase deficiency | | Ornithinaemia | | Hyperprolinemia (HP) | | Snyder-Robinson syndrome | | Guanidinoacetate methyltransferase (GAMT) deficiency | | Creatine deficiency syndrome | | Congenital systemic glutamine deficiency (CSGD) | | Argininosuccinic aciduria (ARGINSA) | | N-acetylglutamate synthase (NAGS) deficiency | | Aminoacylase 1 deficiency |
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| Other DBs |
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| Reference |
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| Authors |
Haake P, Allen GW. |
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| Title |
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase). |
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| Journal |
Proc Natl Acad Sci U S A 68:2691-3 (1971) |
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| Reference |
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| Authors |
Kurihara S, Oda S, Kumagai H, Suzuki H. |
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| Title |
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12. |
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| Journal |
FEMS Microbiol Lett 256:318-23 (2006) |
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| Reference |
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| Authors |
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H. |
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| Title |
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12. |
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| Journal |
J Biol Chem 280:4602-8 (2005) |
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| KO pathway |
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