| Entry |
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| Name |
Glycerophospholipid metabolism
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| Class |
Metabolism; Lipid metabolism
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| Pathway map |
| Glycerophospholipid metabolism |
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| Module |
| Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH: map00564] | | Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH: map00564] | | Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH: map00564] | | Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: map00564] |
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| Disease |
| Lecithin:cholesterol acyltransferase deficiency | | Rhizomelic chondrodysplasia punctata | | Barth syndrome (BTHS) | | Congenital myasthenic syndrome | | Neurodegeneration with brain iron accumulation (NBIA) | | Majeed syndrome | | Acute recurrent myoglobinuria |
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| Other DBs |
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| Reference |
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| Authors |
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML. |
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| Title |
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae. |
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| Journal |
J Bacteriol 174:5702-10 (1992) |
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| Reference |
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| Authors |
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M. |
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| Title |
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase. |
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| Journal |
Biochem Biophys Res Commun 257:50-6 (1999) |
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| Reference |
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| Authors |
Athenstaedt K, Daum G. |
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| Title |
Phosphatidic acid, a key intermediate in lipid metabolism. |
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| Journal |
Eur J Biochem 266:1-16 (1999) |
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| Reference |
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| Authors |
Shields DJ, Lehner R, Agellon LB, Vance DE. |
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| Title |
Membrane topography of human phosphatidylethanolamine N-methyltransferase. |
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| Journal |
J Biol Chem 278:2956-62 (2003) |
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| Reference |
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| Authors |
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O. |
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| Title |
Pathways for phosphatidylcholine biosynthesis in bacteria. |
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| Journal |
Microbiology 149:3461-71 (2003) |
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| Reference |
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| Authors |
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G. |
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| Title |
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae. |
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| Journal |
Biochim Biophys Acta 1686:161-8 (2004) |
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| Reference |
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| Authors |
Hsu L, Jackowski S, Rock CO. |
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| Title |
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity. |
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| Journal |
J Biol Chem 266:13783-8 (1991) |
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| Reference |
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| Authors |
Stone SJ, Vance JE. |
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| Title |
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes. |
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| Journal |
J Biol Chem 275:34534-40 (2000) |
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| KO pathway |
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