| Entry |
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| Name |
Aminoacyl-tRNA biosynthesis
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| Class |
Genetic Information Processing; Translation
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| Pathway map |
| Aminoacyl-tRNA biosynthesis |
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| Module |
| Aminoacyl-tRNA biosynthesis, eukaryotes [PATH: map00970] | | Aminoacyl-tRNA biosynthesis, prokaryotes [PATH: map00970] |
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| Disease |
| Charcot-Marie-Tooth disease (CMT) | | Progressive myoclonic epilepsy (PME) | | Distal hereditary motor neuropathies (dHMN) | | Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL) | | Pontocerebellar hypoplasia | | Myopathy with lactic acidosis and sideroblastic anaemia (MLASA) |
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| Reference |
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| Authors |
Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D |
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| Title |
From one amino acid to another: tRNA-dependent amino acid biosynthesis. |
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| Journal |
Nucleic Acids Res 36:1813-25 (2008) |
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| Reference |
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| Authors |
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D |
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| Title |
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine. |
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| Journal |
Proc Natl Acad Sci U S A 101:12450-4 (2004) |
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| KO pathway |
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