KEGG   PATHWAY: mcl00230
Entry
mcl00230                    Pathway                                
Name
Purine metabolism - Macrococcoides caseolyticum
Class
Metabolism; Nucleotide metabolism
Pathway map
mcl00230  Purine metabolism
mcl00230

Module
mcl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mcl00230]
mcl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mcl00230]
mcl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mcl00230]
mcl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mcl00230]
mcl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mcl00230]
Other DBs
GO: 0006163 0042278
Organism
Macrococcoides caseolyticum [GN:mcl]
Gene
MCCL_1148  ADP-ribose pyrophosphatase homolog [KO:K01515] [EC:3.6.1.13 3.6.1.-]
MCCL_1821  conserved hypothetical protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
MCCL_1794  drm; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
MCCL_0779  truncated phosphomannomutase [KO:K01835] [EC:5.4.2.2]
MCCL_1912  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MCCL_0693  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MCCL_0697  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
MCCL_0695  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MCCL_0692  purL; phosphoribosylformylglycinamidine synthetase PurL [KO:K23269] [EC:6.3.5.3]
MCCL_0690  conserved hypothetical protein [KO:K23264] [EC:6.3.5.3]
MCCL_0691  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MCCL_0694  purM; phosphoribosylformylglycinamidine cyclo-ligase homolog [KO:K01933] [EC:6.3.3.1]
MCCL_0688  conserved hypothetical protein [KO:K01589] [EC:6.3.4.18]
MCCL_0687  conserved hypothetical protein [KO:K01588] [EC:5.4.99.18]
MCCL_0689  purC; phosphoribosylaminoimidazole succinocarboxamide synthetase [KO:K01923] [EC:6.3.2.6]
MCCL_1646  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MCCL_0696  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MCCL_1272  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MCCL_0552  conserved hypothetical protein [KO:K01081] [EC:3.1.3.5]
MCCL_0129  purine nucleoside phosphorylase homolog [KO:K03784] [EC:2.4.2.1]
MCCL_0759  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
MCCL_1903  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MCCL_1942  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MCCL_1120  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MCCL_1314  conserved hypothetical protein [KO:K01519] [EC:3.6.1.66]
MCCL_1944  xprT; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
MCCL_1941  guaA; bifunctional GMP synthase/glutamine amidotransferase protein [KO:K01951] [EC:6.3.5.2]
MCCL_0794  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MCCL_0483  nrdE; ribonucleoside-diphosphate reductase major subunit [KO:K00525] [EC:1.17.4.1]
MCCL_0484  nrdF; ribonucleoside-diphosphate reductase minor subunit [KO:K00526] [EC:1.17.4.1]
MCCL_1815  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
MCCL_1851  deoxypurine kinase homolog [KO:K15518] [EC:2.7.1.113]
MCCL_1271  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MCCL_1576  exopolyphosphatase homolog [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MCCL_0620  truncated GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
MCCL_0428  conserved hypothetical protein [KO:K07816] [EC:2.7.6.5]
MCCL_0019  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
MCCL_1852  deoxyadenosine kinase homolog [KO:K15519] [EC:2.7.1.76 2.7.1.74]
MCCL_0877  conserved hypothetical protein [KO:K09769] [EC:3.1.4.16]
MCCL_0216  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mcl00030  Pentose phosphate pathway
mcl00220  Arginine biosynthesis
mcl00250  Alanine, aspartate and glutamate metabolism
mcl00260  Glycine, serine and threonine metabolism
mcl00340  Histidine metabolism
mcl00630  Glyoxylate and dicarboxylate metabolism
mcl00730  Thiamine metabolism
mcl00740  Riboflavin metabolism
mcl00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG GENES (40)   
All databases (41)   

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