KEGG PATHWAY: mmc00630

PATHWAY: mmc00630

Entry

mmc00630 Pathway

Name

Glyoxylate and dicarboxylate metabolism - Mycobacterium sp. MCS

Class

Metabolism; Carbohydrate metabolism

Pathway map

mmc00630

Glyoxylate and dicarboxylate metabolism

Organism

Mycobacterium sp. MCS [GN:mmc]

Gene

Mmcs_0187	isocitrate lyase; K01637 isocitrate lyase [EC:4.1.3.1] [KO:K01637] [EC:4.1.3.1]
Mmcs_0636	isocitrate lyase; K01637 isocitrate lyase [EC:4.1.3.1] [KO:K01637] [EC:4.1.3.1]
Mmcs_2817	malate synthase G; K01638 malate synthase [EC:2.3.3.9] [KO:K01638] [EC:2.3.3.9]
Mmcs_4456	gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
Mmcs_4459	citrate synthase 2; K01647 citrate synthase [EC:2.3.3.1] [KO:K01647] [EC:2.3.3.1]
Mmcs_2449	aconitate hydratase; K01681 aconitate hydratase [EC:4.2.1.3] [KO:K01681] [EC:4.2.1.3]
Mmcs_2792	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_4678	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_4690	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_3224	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_3796	acetyl-CoA C-acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_3864	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_4152	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_4325	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_4493	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_1517	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_1758	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_1769	acetyl-CoA C-acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_3099	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_4636	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_0241	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mmcs_3865	methylmalonyl-CoA epimerase; K05606 methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] [KO:K05606] [EC:5.1.99.1]
Mmcs_1294	carboxyl transferase; K01966 propionyl-CoA carboxylase beta chain [EC:6.4.1.3] [KO:K01966] [EC:6.4.1.3]
Mmcs_3122	methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]
Mmcs_3123	methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]
Mmcs_1002	(S)-2-hydroxy-acid oxidase; K00104 glycolate oxidase [EC:1.1.3.15] [KO:K00104] [EC:1.1.3.15]
Mmcs_5060	catalase; K03781 catalase [EC:1.11.1.6] [KO:K03781] [EC:1.11.1.6]
Mmcs_2057	glutamate--ammonia ligase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_5344	L-glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_2754	glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_4892	glutamate--ammonia ligase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_3320	L-glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_3328	L-glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_0870	glutamate--ammonia ligase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_0512	glutamate--ammonia ligase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_0233	glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
Mmcs_4131	glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Mmcs_2845	glycine cleavage system protein H; K02437 glycine cleavage system H protein [KO:K02437]
Mmcs_5347	6-phosphogluconate dehydrogenase protein; K00042 2-hydroxy-3-oxopropionate reductase [EC:1.1.1.60] [KO:K00042] [EC:1.1.1.60]
Mmcs_2001	glycerate kinase; K00865 glycerate kinase [EC:2.7.1.31] [KO:K00865] [EC:2.7.1.31]
Mmcs_2573	tartrate dehydrogenase; K07246 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83] [KO:K07246] [EC:1.1.1.83 4.1.1.73 1.1.1.93]
Mmcs_2009	formate dehydrogenase; K00122 formate dehydrogenase [EC:1.2.1.2] [KO:K00122] [EC:1.2.1.2]
Mmcs_2721	formate dehydrogenase; K00122 formate dehydrogenase [EC:1.2.1.2] [KO:K00122] [EC:1.2.1.2]
Mmcs_3942	formate dehydrogenase; K00122 formate dehydrogenase [EC:1.2.1.2] [KO:K00122] [EC:1.2.1.2]
Mmcs_5220	formate dehydrogenase; K00123 formate dehydrogenase, alpha subunit [EC:1.2.1.2] [KO:K00123] [EC:1.2.1.2]
Mmcs_5221	formate dehydrogenase subunit beta; K00124 formate dehydrogenase, beta subunit [KO:K00124]
Mmcs_2262	formamidase; K01455 formamidase [EC:3.5.1.49] [KO:K01455] [EC:3.5.1.49]

Compound

C00007	Oxygen
C00011	CO2
C00014	Ammonia
C00022	Pyruvate
C00024	Acetyl-CoA
C00025	L-Glutamate
C00026	2-Oxoglutarate
C00027	Hydrogen peroxide
C00036	Oxaloacetate
C00037	Glycine
C00042	Succinate
C00048	Glyoxylate
C00058	Formate
C00064	L-Glutamine
C00065	L-Serine
C00091	Succinyl-CoA
C00100	Propanoyl-CoA
C00136	Butanoyl-CoA
C00149	(S)-Malate
C00158	Citrate
C00160	Glycolate
C00168	Hydroxypyruvate
C00197	3-Phospho-D-glycerate
C00209	Oxalate
C00258	D-Glycerate
C00266	Glycolaldehyde
C00311	Isocitrate
C00313	Oxalyl-CoA
C00332	Acetoacetyl-CoA
C00417	cis-Aconitate
C00552	meso-Tartaric acid
C00683	(S)-Methylmalonyl-CoA
C00798	Formyl-CoA
C00877	Crotonoyl-CoA
C00888	Pentanoyl-CoA
C00898	(R,R)-Tartaric acid
C00975	Dihydroxyfumarate
C00988	2-Phosphoglycolate
C01127	4-Hydroxy-2-oxoglutarate
C01146	2-Hydroxy-3-oxopropanoate
C01182	D-Ribulose 1,5-bisphosphate
C01213	(R)-Methylmalonyl-CoA
C01380	Ethylene glycol
C01989	3-Ethylmalate
C01990	3-Oxalomalate
C02123	3-Propylmalate
C02405	Formyl phosphate
C03217	2-Hydroxy-3-oxoadipate
C03459	2-Hydroxy-3-oxosuccinate
C03548	trans-2,3-Epoxysuccinate
C03561	(R)-3-Hydroxybutanoyl-CoA
C04348	(3S)-3-Carboxy-3-hydroxypropanoyl-CoA
C06027	L-erythro-3-Methylmalyl-CoA
C06028	Mesaconyl-CoA
C06049	N-Formylderivatives
C18026	(2S)-Ethylmalonyl-CoA
C18324	(2S)-Methylsuccinyl-CoA
C20238	(2R)-Ethylmalonyl-CoA

Reference

PMID:10978349 (EC5.3.1.22)

Authors

Njau RK, Herndon CA, Hawes JW.

Title

Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilusinfluenzae.

Journal

J Biol Chem 275:38780-6 (2000)

Reference

PMID:18065535

Authors

Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G

Title

Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.

Journal

J Bacteriol 190:1366-74 (2008)

Reference

PMID:18819910

Authors

Erb TJ, Retey J, Fuchs G, Alber BE

Title

Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.

Journal

J Biol Chem 283:32283-93 (2008)

KO pathway

ko00630

All links

Pathway (1)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG GENES (47)   
All databases (49)   

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