KEGG   PATHWAY: mmu04060Help
Entry
mmu04060                    Pathway                                

Name
Cytokine-cytokine receptor interaction - Mus musculus (mouse)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
BRITE hierarchy
Pathway map
Cytokine-cytokine receptor interaction
mmu04060

All organismsOrtholog table
Organism
Mus musculus (mouse) [GN:mmu]
Gene
14825  
Cxcl1; chemokine (C-X-C motif) ligand 1 [KO:K05505]
20310  
Cxcl2; chemokine (C-X-C motif) ligand 2 [KO:K05505]
20311  
Cxcl5; chemokine (C-X-C motif) ligand 5 [KO:K05506]
57349  
Ppbp; pro-platelet basic protein [KO:K10029]
17329  
Cxcl9; chemokine (C-X-C motif) ligand 9 [KO:K05416]
15945  
Cxcl10; chemokine (C-X-C motif) ligand 10 [KO:K12671]
56066  
Cxcl11; chemokine (C-X-C motif) ligand 11 [KO:K12672]
20315  
Cxcl12; chemokine (C-X-C motif) ligand 12 [KO:K10031]
55985  
Cxcl13; chemokine (C-X-C motif) ligand 13 [KO:K10032]
66102  
Cxcl16; chemokine (C-X-C motif) ligand 16 [KO:K10035]
20309  
Cxcl15; chemokine (C-X-C motif) ligand 15 [KO:K10034]
56744  
Pf4; platelet factor 4 [KO:K05407]
57266  
Cxcl14; chemokine (C-X-C motif) ligand 14 [KO:K10033]
16963  
Xcl1; chemokine (C motif) ligand 1 [KO:K05507]
20312  
Cx3cl1; chemokine (C-X3-C motif) ligand 1 [KO:K05508]
20290  
Ccl1; chemokine (C-C motif) ligand 1 [KO:K05514]
20299  
Ccl22; chemokine (C-C motif) ligand 22 [KO:K05514]
56221  
Ccl24; chemokine (C-C motif) ligand 24 [KO:K05514]
20295  
Ccl17; chemokine (C-C motif) ligand 17 [KO:K05514]
20297  
Ccl20; chemokine (C-C motif) ligand 20 [KO:K14625]
20300  
Ccl25; chemokine (C-C motif) ligand 25 [KO:K13072]
24047  
Ccl19; chemokine (C-C motif) ligand 19 [KO:K05512]
Gm2023; predicted gene 2023 [KO:K05512]
Gm21541; predicted gene, 21541 [KO:K16062]
Gm13304; predicted gene 13304 [KO:K16062]
Gm10591; predicted gene 10591 [KO:K16062]
Ccl21b; chemokine (C-C motif) ligand 21B (leucine) [KO:K16062]
C-C motif chemokine 21c; K16062 C-C motif chemokine 21 [KO:K16062]
C-C motif chemokine 21c; K16062 C-C motif chemokine 21 [KO:K16062]
65956  
Ccl21c; chemokine (C-C motif) ligand 21C (leucine) [KO:K16062]
Gm1987; predicted gene 1987 [KO:K16062]
18829  
Ccl21a; chemokine (C-C motif) ligand 21A (serine) [KO:K16062]
20296  
Ccl2; chemokine (C-C motif) ligand 2 [KO:K14624]
20293  
Ccl12; chemokine (C-C motif) ligand 12 [KO:K14624]
20303  
Ccl4; chemokine (C-C motif) ligand 4 [KO:K12964]
20302  
Ccl3; chemokine (C-C motif) ligand 3 [KO:K05408]
20306  
Ccl7; chemokine (C-C motif) ligand 7 [KO:K05509]
20304  
Ccl5; chemokine (C-C motif) ligand 5 [KO:K12499]
20307  
Ccl8; chemokine (C-C motif) ligand 8 [KO:K16596]
20292  
Ccl11; chemokine (C-C motif) ligand 11 [KO:K16597]
56838  
Ccl28; chemokine (C-C motif) ligand 28 [KO:K05513]
20301  
Ccl27a; chemokine (C-C motif) ligand 27A [KO:K16598]
Ccl27b; chemokine (C-C motif) ligand 27b [KO:K16598]
Gm20878; predicted gene, 20878 [KO:K16598]
Gm13306; predicted gene 13306 [KO:K16598]
c-C motif chemokine 27-like; K16598 C-C motif chemokine 27 [KO:K16598]
Gm2506; predicted gene 2506 [KO:K16598]
Gm21586; predicted gene, 21586 [KO:K16598]
621580  
Gm13308; predicted gene 13308 [KO:K16598]
20305  
Ccl6; chemokine (C-C motif) ligand 6 [KO:K05510]
20308  
Ccl9; chemokine (C-C motif) ligand 9 [KO:K05510]
16193  
Il6; interleukin 6 [KO:K05405]
16156  
Il11; interleukin 11 [KO:K05417]
18413  
Osm; oncostatin M [KO:K05418]
16878  
Lif; leukemia inhibitory factor [KO:K05419]
12803  
Cntf; ciliary neurotrophic factor [KO:K05420]
56708  
Clcf1; cardiotrophin-like cytokine factor 1 [KO:K05421]
13019  
Ctf1; cardiotrophin 1 [KO:K05422]
12985  
Csf3; colony stimulating factor 3 (granulocyte) [KO:K05423]
16846  
Lep; leptin [KO:K05424]
16189  
Il4; interleukin 4 [KO:K05430]
16163  
Il13; interleukin 13 [KO:K05435]
16159  
Il12a; interleukin 12a [KO:K05406]
16160  
Il12b; interleukin 12b [KO:K05425]
83430  
Il23a; interleukin 23, alpha subunit p19 [KO:K05426]
12981  
Csf2; colony stimulating factor 2 (granulocyte-macrophage) [KO:K05427]
16187  
Il3; interleukin 3 [KO:K04736]
16191  
Il5; interleukin 5 [KO:K05428]
16183  
Il2; interleukin 2 [KO:K05429]
16196  
Il7; interleukin 7 [KO:K05431]
16198  
Il9; interleukin 9 [KO:K05432]
16168  
Il15; interleukin 15 [KO:K05433]
60505  
Il21; interleukin 21 [KO:K05434]
53603  
Tslp; thymic stromal lymphopoietin [KO:K05436]
13856  
Epo; erythropoietin [KO:K05437]
19109  
Prl; prolactin [KO:K05439]
21832  
Thpo; thrombopoietin [KO:K06854]
54635  
Pdgfc; platelet-derived growth factor, C polypeptide [KO:K05450]
71785  
Pdgfd; platelet-derived growth factor, D polypeptide [KO:K05450]
18590  
Pdgfa; platelet derived growth factor, alpha [KO:K04359]
18591  
Pdgfb; platelet derived growth factor, B polypeptide [KO:K17386]
22339  
Vegfa; vascular endothelial growth factor A [KO:K05448]
22340  
Vegfb; vascular endothelial growth factor B [KO:K16858]
22341  
Vegfc; vascular endothelial growth factor C [KO:K05449]
14205  
Vegfd; vascular endothelial growth factor D [KO:K05449]
15234  
Hgf; hepatocyte growth factor [KO:K05460]
13645  
Egf; epidermal growth factor [KO:K04357]
12977  
Csf1; colony stimulating factor 1 (macrophage) [KO:K05453]
17311  
Kitl; kit ligand [KO:K05461]
14256  
Flt3l; FMS-like tyrosine kinase 3 ligand [KO:K05454]
15962  
Ifna1; interferon alpha 1 [KO:K05414]
15965  
Ifna2; interferon alpha 2 [KO:K05414]
15967  
Ifna4; interferon alpha 4 [KO:K05414]
15968  
Ifna5; interferon alpha 5 [KO:K05414]
15969  
Ifna6; interferon alpha 6 [KO:K05414]
15970  
Ifna7; interferon alpha 7 [KO:K05414]
15972  
Ifna9; interferon alpha 9 [KO:K05414]
15964  
Ifna11; interferon alpha 11 [KO:K05414]
242519  
Ifna12; interferon alpha 12 [KO:K05414]
230396  
Ifna13; interferon alpha 13 [KO:K05414]
404549  
Ifna14; interferon alpha 14 [KO:K05414]
15974  
Ifnab; interferon alpha B [KO:K05414]
242517  
Ifna15; interferon alpha 15 [KO:K05414]
15977  
Ifnb1; interferon beta 1, fibroblast [KO:K05415]
387510  
Ifnk; interferon kappa [KO:K05441]
230405  
Ifne; interferon epsilon [KO:K05442]
15978  
Ifng; interferon gamma [KO:K04687]
16153  
Il10; interleukin 10 [KO:K05443]
329244  
Il19; interleukin 19 [KO:K05444]
58181  
Il20; interleukin 20 [KO:K05444]
93672  
Il24; interleukin 24 [KO:K05444]
50929  
Il22; interleukin 22 [KO:K05445]
326623  
Tnfsf15; tumor necrosis factor (ligand) superfamily, member 15 [KO:K05478]
22035  
Tnfsf10; tumor necrosis factor (ligand) superfamily, member 10 [KO:K04721]
21943  
Tnfsf11; tumor necrosis factor (ligand) superfamily, member 11 [KO:K05473]
21944  
Tnfsf12; tumor necrosis factor (ligand) superfamily, member 12 [KO:K05474]
21926  
Tnf; tumor necrosis factor [KO:K03156]
16992  
Lta; lymphotoxin A [KO:K05468]
16994  
Ltb; lymphotoxin B [KO:K03157]
50930  
Tnfsf14; tumor necrosis factor (ligand) superfamily, member 14 [KO:K05477]
14103  
Fasl; Fas ligand (TNF superfamily, member 6) [KO:K04389]
21947  
Cd40lg; CD40 ligand [KO:K03161]
21948  
Cd70; CD70 antigen [KO:K05470]
21949  
Tnfsf8; tumor necrosis factor (ligand) superfamily, member 8 [KO:K05471]
21950  
Tnfsf9; tumor necrosis factor (ligand) superfamily, member 9 [KO:K05472]
22164  
Tnfsf4; tumor necrosis factor (ligand) superfamily, member 4 [KO:K05469]
240873  
Tnfsf18; tumor necrosis factor (ligand) superfamily, member 18 [KO:K05479]
69583  
Tnfsf13; tumor necrosis factor (ligand) superfamily, member 13 [KO:K05475]
24099  
Tnfsf13b; tumor necrosis factor (ligand) superfamily, member 13b [KO:K05476]
13607  
Eda; ectodysplasin-A [KO:K05480]
21803  
Tgfb1; transforming growth factor, beta 1 [KO:K13375]
21808  
Tgfb2; transforming growth factor, beta 2 [KO:K13376]
21809  
Tgfb3; transforming growth factor, beta 3 [KO:K13377]
16323  
Inhba; inhibin beta-A [KO:K04667]
16324  
Inhbb; inhibin beta-B [KO:K04667]
16325  
Inhbc; inhibin beta-C [KO:K04667]
16326  
Inhbe; inhibin beta-E [KO:K04667]
11705  
Amh; anti-Mullerian hormone [KO:K04665]
12156  
Bmp2; bone morphogenetic protein 2 [KO:K04662]
12162  
Bmp7; bone morphogenetic protein 7 [KO:K16621]
14563  
Gdf5; growth differentiation factor 5 [KO:K04664]
16171  
Il17a; interleukin 17A [KO:K05489]
56069  
Il17b; interleukin 17B [KO:K05490]
140806  
Il25; interleukin 25 [KO:K05493]
16175  
Il1a; interleukin 1 alpha [KO:K04383]
16176  
Il1b; interleukin 1 beta [KO:K04519]
16173  
Il18; interleukin 18 [KO:K05482]
12765  
Cxcr2; chemokine (C-X-C motif) receptor 2 [KO:K05050]
227288  
Cxcr1; chemokine (C-X-C motif) receptor 1 [KO:K04175]
12766  
Cxcr3; chemokine (C-X-C motif) receptor 3 [KO:K04188]
12767  
Cxcr4; chemokine (C-X-C motif) receptor 4 [KO:K04189]
12145  
Cxcr5; chemokine (C-X-C motif) receptor 5 [KO:K04190]
80901  
Cxcr6; chemokine (C-X-C motif) receptor 6 [KO:K04191]
12778  
Ackr3; atypical chemokine receptor 3 [KO:K04304]
23832  
Xcr1; chemokine (C motif) receptor 1 [KO:K04193]
13051  
Cx3cr1; chemokine (C-X3-C motif) receptor 1 [KO:K04192]
12776  
Ccr8; chemokine (C-C motif) receptor 8 [KO:K04183]
12458  
Ccr6; chemokine (C-C motif) receptor 6 [KO:K04181]
12769  
Ccr9; chemokine (C-C motif) receptor 9 [KO:K04184]
12773  
Ccr4; chemokine (C-C motif) receptor 4 [KO:K04179]
12775  
Ccr7; chemokine (C-C motif) receptor 7 [KO:K04182]
12772  
Ccr2; chemokine (C-C motif) receptor 2 [KO:K04177]
12774  
Ccr5; chemokine (C-C motif) receptor 5 [KO:K04180]
12768  
Ccr1; chemokine (C-C motif) receptor 1 [KO:K04176]
12770  
Ccr1l1; chemokine (C-C motif) receptor 1-like 1 [KO:K04176]
12771  
Ccr3; chemokine (C-C motif) receptor 3 [KO:K04178]
12777  
Ccr10; chemokine (C-C motif) receptor 10 [KO:K04185]
16194  
Il6ra; interleukin 6 receptor, alpha [KO:K05055]
16195  
Il6st; interleukin 6 signal transducer [KO:K05060]
16157  
Il11ra1; interleukin 11 receptor, alpha chain 1 [KO:K05056]
16158  
Il11ra2; interleukin 11 receptor, alpha chain 2 [KO:K05056]
interleukin-11 receptor subunit alpha-2-like; K05056 interleukin 11 receptor alpha [KO:K05056]
Gm13305; predicted gene 13305 [KO:K05056]
Gm2002; predicted gene 2002 [KO:K05056]
16880  
Lifr; leukemia inhibitory factor receptor [KO:K05058]
18414  
Osmr; oncostatin M receptor [KO:K05057]
12804  
Cntfr; ciliary neurotrophic factor receptor [KO:K05059]
12986  
Csf3r; colony stimulating factor 3 receptor (granulocyte) [KO:K05061]
16847  
Lepr; leptin receptor [KO:K05062]
16190  
Il4ra; interleukin 4 receptor, alpha [KO:K05071]
16164  
Il13ra1; interleukin 13 receptor, alpha 1 [KO:K05076]
16161  
Il12rb1; interleukin 12 receptor, beta 1 [KO:K05063]
16162  
Il12rb2; interleukin 12 receptor, beta 2 [KO:K05064]
209590  
Il23r; interleukin 23 receptor [KO:K05065]
12982  
Csf2ra; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) [KO:K05066]
12984  
Csf2rb2; colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) [KO:K04738]
12983  
Csf2rb; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [KO:K04738]
16188  
Il3ra; interleukin 3 receptor, alpha chain [KO:K04737]
16192  
Il5ra; interleukin 5 receptor, alpha [KO:K05067]
16184  
Il2ra; interleukin 2 receptor, alpha chain [KO:K05068]
16185  
Il2rb; interleukin 2 receptor, beta chain [KO:K05069]
16186  
Il2rg; interleukin 2 receptor, gamma chain [KO:K05070]
16197  
Il7r; interleukin 7 receptor [KO:K05072]
16199  
Il9r; interleukin 9 receptor [KO:K05073]
16169  
Il15ra; interleukin 15 receptor, alpha chain [KO:K05074]
60504  
Il21r; interleukin 21 receptor [KO:K05075]
57914  
Crlf2; cytokine receptor-like factor 2 [KO:K05078]
13857  
Epor; erythropoietin receptor [KO:K05079]
14600  
Ghr; growth hormone receptor [KO:K05080]
19116  
Prlr; prolactin receptor [KO:K05081]
17480  
Mpl; myeloproliferative leukemia virus oncogene [KO:K05082]
18595  
Pdgfra; platelet derived growth factor receptor, alpha polypeptide [KO:K04363] [EC:2.7.10.1]
18596  
Pdgfrb; platelet derived growth factor receptor, beta polypeptide [KO:K05089] [EC:2.7.10.1]
14254  
Flt1; FMS-like tyrosine kinase 1 [KO:K05096] [EC:2.7.10.1]
16542  
Kdr; kinase insert domain protein receptor [KO:K05098] [EC:2.7.10.1]
14257  
Flt4; FMS-like tyrosine kinase 4 [KO:K05097] [EC:2.7.10.1]
17295  
Met; met proto-oncogene [KO:K05099] [EC:2.7.10.1]
13649  
Egfr; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
12978  
Csf1r; colony stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
16590  
Kit; kit oncogene [KO:K05091] [EC:2.7.10.1]
14255  
Flt3; FMS-like tyrosine kinase 3 [KO:K05092] [EC:2.7.10.1]
15975  
Ifnar1; interferon (alpha and beta) receptor 1 [KO:K05130]
15976  
Ifnar2; interferon (alpha and beta) receptor 2 [KO:K05131]
15979  
Ifngr1; interferon gamma receptor 1 [KO:K05132]
15980  
Ifngr2; interferon gamma receptor 2 [KO:K05133]
16154  
Il10ra; interleukin 10 receptor, alpha [KO:K05134]
16155  
Il10rb; interleukin 10 receptor, beta [KO:K05135]
237313  
Il20ra; interleukin 20 receptor, alpha [KO:K05136]
213208  
Il20rb; interleukin 20 receptor beta [KO:K05137]
230828  
Il22ra1; interleukin 22 receptor, alpha 1 [KO:K05138]
237310  
Il22ra2; interleukin 22 receptor, alpha 2 [KO:K05139]
242700  
Ifnlr1; interferon lambda receptor 1 [KO:K05140]
21933  
Tnfrsf10b; tumor necrosis factor receptor superfamily, member 10b [KO:K04722]
18383  
Tnfrsf11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) [KO:K05148]
21934  
Tnfrsf11a; tumor necrosis factor receptor superfamily, member 11a, NFKB activator [KO:K05147]
85030  
Tnfrsf25; tumor necrosis factor receptor superfamily, member 25 [KO:K05160]
27279  
Tnfrsf12a; tumor necrosis factor receptor superfamily, member 12a [KO:K05149]
94185  
Tnfrsf21; tumor necrosis factor receptor superfamily, member 21 [KO:K05157]
18053  
Ngfr; nerve growth factor receptor (TNFR superfamily, member 16) [KO:K02583]
21938  
Tnfrsf1b; tumor necrosis factor receptor superfamily, member 1b [KO:K05141]
21937  
Tnfrsf1a; tumor necrosis factor receptor superfamily, member 1a [KO:K03158]
17000  
Ltbr; lymphotoxin B receptor [KO:K03159]
230979  
Tnfrsf14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) [KO:K05152]
14102  
Fas; Fas (TNF receptor superfamily member 6) [KO:K04390]
21939  
Cd40; CD40 antigen [KO:K03160]
21940  
Cd27; CD27 antigen [KO:K05144]
21941  
Tnfrsf8; tumor necrosis factor receptor superfamily, member 8 [KO:K05145]
21942  
Tnfrsf9; tumor necrosis factor receptor superfamily, member 9 [KO:K05146]
22163  
Tnfrsf4; tumor necrosis factor receptor superfamily, member 4 [KO:K05142]
21936  
Tnfrsf18; tumor necrosis factor receptor superfamily, member 18 [KO:K05154]
21935  
Tnfrsf17; tumor necrosis factor receptor superfamily, member 17 [KO:K05153]
57916  
Tnfrsf13b; tumor necrosis factor receptor superfamily, member 13b [KO:K05150]
72049  
Tnfrsf13c; tumor necrosis factor receptor superfamily, member 13c [KO:K05151]
13608  
Edar; ectodysplasin-A receptor [KO:K05162]
245527  
Eda2r; ectodysplasin A2 receptor [KO:K05163]
29820  
Tnfrsf19; tumor necrosis factor receptor superfamily, member 19 [KO:K05155]
320100  
Relt; RELT tumor necrosis factor receptor [KO:K05156]
21813  
Tgfbr2; transforming growth factor, beta receptor II [KO:K04388] [EC:2.7.11.30]
21812  
Tgfbr1; transforming growth factor, beta receptor I [KO:K04674] [EC:2.7.11.30]
11480  
Acvr2a; activin receptor IIA [KO:K04670] [EC:2.7.11.30]
11481  
Acvr2b; activin receptor IIB [KO:K13596] [EC:2.7.11.30]
11477  
Acvr1; activin A receptor, type 1 [KO:K04675] [EC:2.7.11.30]
11479  
Acvr1b; activin A receptor, type 1B [KO:K13567] [EC:2.7.11.30]
110542  
Amhr2; anti-Mullerian hormone type 2 receptor [KO:K04672] [EC:2.7.11.30]
12168  
Bmpr2; bone morphogenetic protein receptor, type II (serine/threonine kinase) [KO:K04671] [EC:2.7.11.30]
12166  
Bmpr1a; bone morphogenetic protein receptor, type 1A [KO:K04673] [EC:2.7.11.30]
12167  
Bmpr1b; bone morphogenetic protein receptor, type 1B [KO:K13578] [EC:2.7.11.30]
16172  
Il17ra; interleukin 17 receptor A [KO:K05164]
50905  
Il17rb; interleukin 17 receptor B [KO:K05165]
16177  
Il1r1; interleukin 1 receptor, type I [KO:K04386]
16180  
Il1rap; interleukin 1 receptor accessory protein [KO:K04723]
16178  
Il1r2; interleukin 1 receptor, type II [KO:K04387]
16182  
Il18r1; interleukin 18 receptor 1 [KO:K05173]
16174  
Il18rap; interleukin 18 receptor accessory protein [KO:K05174]
Reference
  Authors
Oppenheim JJ, Feldman M (ed).
  Title
Cytokine Reference
  Journal
Academic Press (2001)
Reference
  Authors
Thomson AW, Lotze MT (ed).
  Title
The Cytokine Handbook (Fourth edition)
  Journal
Academic Press (2003)
Reference
  Authors
Zlotnik A, Yoshie O.
  Title
Chemokines: a new classification system and their role in immunity.
  Journal
Immunity 12:121-7 (2000)
Reference
  Authors
Ozaki K, Leonard WJ.
  Title
Cytokine and cytokine receptor pleiotropy and redundancy.
  Journal
J Biol Chem 277:29355-8 (2002)
Reference
  Authors
Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW.
  Title
Signaling through the JAK/STAT pathway, recent advances and future challenges.
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Gene 285:1-24 (2002)
Reference
  Authors
Li X, Eriksson U.
  Title
Novel PDGF family members: PDGF-C and PDGF-D.
  Journal
Cytokine Growth Factor Rev 14:91-8 (2003)
Reference
  Authors
Li X, Eriksson U.
  Title
Novel VEGF family members: VEGF-B, VEGF-C and VEGF-D.
  Journal
Int J Biochem Cell Biol 33:421-6 (2001)
Reference
  Authors
Zachary I, Gliki G.
  Title
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family.
  Journal
Cardiovasc Res 49:568-81 (2001)
Reference
  Authors
Dey A, She H, Kim L, Boruch A, Guris DL, Carlberg K, Sebti SM, Woodley DT, Imamoto A, Li W.
  Title
Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression.
  Journal
Mol Biol Cell 11:3835-48 (2000)
Reference
  Authors
Pestka S, Krause CD, Sarkar D, Walter MR, Shi Y, Fisher PB.
  Title
Interleukin-10 and related cytokines and receptors.
  Journal
Annu Rev Immunol 22:929-79 (2004)
Reference
  Authors
Bodmer JL, Schneider P, Tschopp J.
  Title
The molecular architecture of the TNF superfamily.
  Journal
Trends Biochem Sci 27:19-26 (2002)
Reference
PMID:9395284
  Authors
Derynck R, Feng XH.
  Title
TGF-beta receptor signaling.
  Journal
Biochim Biophys Acta 1333:F105-50 (1997)
Reference
PMID:7791754
  Authors
Liu F, Ventura F, Doody J, Massague J.
  Title
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs.
  Journal
Mol Cell Biol 15:3479-86 (1995)
Reference
PMID:9759503
  Authors
Massague J.
  Title
TGF-beta signal transduction.
  Journal
Annu Rev Biochem 67:753-91 (1998)
Reference
  Authors
Massague J.
  Title
How cells read TGF-beta signals.
  Journal
Nat Rev Mol Cell Biol 1:169-78 (2000)
Reference
  Authors
Moseley TA, Haudenschild DR, Rose L, Reddi AH.
  Title
Interleukin-17 family and IL-17 receptors.
  Journal
Cytokine Growth Factor Rev 14:155-74 (2003)
Reference
  Authors
Martin MU, Wesche H.
  Title
Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family.
  Journal
Biochim Biophys Acta 1592:265-80 (2002)
Reference
PMID:9862719
  Authors
Lang D, Knop J, Wesche H, Raffetseder U, Kurrle R, Boraschi D, Martin MU.
  Title
The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness.
  Journal
J Immunol 161:6871-7 (1998)
KO pathway
 

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