KEGG PATHWAY: mno00620

PATHWAY: mno00620

Entry

mno00620 Pathway

Name

Pyruvate metabolism - Methylobacterium nodulans

Class

Metabolism; Carbohydrate metabolism

Pathway map

mno00620

Pyruvate metabolism

Module

mno_M00307	Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:mno00620]
mno_M00310	Pyruvate:ferredoxin oxidoreductase [PATH:mno00620]

Other DBs

BSID:

81059

GO:

0006090

Organism

Methylobacterium nodulans [GN:mno]

Gene

Mnod_1158	AMP-dependent synthetase and ligase; K01895 acetyl-CoA synthetase [EC:6.2.1.1] [KO:K01895] [EC:6.2.1.1]
Mnod_3983	AMP-dependent synthetase and ligase; K01895 acetyl-CoA synthetase [EC:6.2.1.1] [KO:K01895] [EC:6.2.1.1]
Mnod_4783	acetyl-CoA synthetase; K01895 acetyl-CoA synthetase [EC:6.2.1.1] [KO:K01895] [EC:6.2.1.1]
Mnod_5208	acetyl-CoA synthetase; K01895 acetyl-CoA synthetase [EC:6.2.1.1] [KO:K01895] [EC:6.2.1.1]
Mnod_5820	2-oxoacid dehydrogenase subunit E1; K00163 pyruvate dehydrogenase E1 component [EC:1.2.4.1] [KO:K00163] [EC:1.2.4.1]
Mnod_7191	aceE; pyruvate dehydrogenase subunit E1 [KO:K00163] [EC:1.2.4.1]
Mnod_6515	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] [KO:K00161] [EC:1.2.4.1]
Mnod_3376	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; K00161 pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] [KO:K00161] [EC:1.2.4.1]
Mnod_6516	pyruvate dehydrogenase subunit beta; K00162 pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] [KO:K00162] [EC:1.2.4.1]
Mnod_3377	transketolase central region; K00162 pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] [KO:K00162] [EC:1.2.4.1]
Mnod_6518	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] [KO:K00627] [EC:2.3.1.12]
Mnod_3378	branched-chain alpha-keto acid dehydrogenase subunit E2; K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] [KO:K00627] [EC:2.3.1.12]
Mnod_7192	hypothetical protein; K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] [KO:K00627] [EC:2.3.1.12]
Mnod_6519	dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4] [KO:K00382] [EC:1.8.1.4]
Mnod_1130	dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4] [KO:K00382] [EC:1.8.1.4]
Mnod_7193	dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4] [KO:K00382] [EC:1.8.1.4]
Mnod_0408	acetate kinase; K00925 acetate kinase [EC:2.7.2.1] [KO:K00925] [EC:2.7.2.1]
Mnod_6909	acetate kinase; K00925 acetate kinase [EC:2.7.2.1] [KO:K00925] [EC:2.7.2.1]
Mnod_6908	phosphate acetyl/butaryl transferase; K00625 phosphate acetyltransferase [EC:2.3.1.8] [KO:K00625] [EC:2.3.1.8]
Mnod_0409	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; K00625 phosphate acetyltransferase [EC:2.3.1.8] [KO:K00625] [EC:2.3.1.8]
Mnod_1446	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
Mnod_5962	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
Mnod_3090	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
Mnod_2104	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
Mnod_0655	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
Mnod_4594	acetyl-CoA carboxylase carboxyltransferase subunit alpha; K01962 acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2] [KO:K01962] [EC:6.4.1.2]
Mnod_0897	acetyl-CoA carboxylase; K02160 acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
Mnod_6043	acetyl-CoA carboxylase; K02160 acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
Mnod_6042	acetyl-CoA carboxylase; K01961 acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] [KO:K01961] [EC:6.3.4.14 6.4.1.2]
Mnod_0898	acetyl-CoA carboxylase; K01961 acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] [KO:K01961] [EC:6.3.4.14 6.4.1.2]
Mnod_1622	acetyl-CoA carboxylase; K01963 acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2] [KO:K01963] [EC:6.4.1.2]
Mnod_1891	acylphosphatase; K01512 acylphosphatase [EC:3.6.1.7] [KO:K01512] [EC:3.6.1.7]
Mnod_7559	aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
Mnod_8483	aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
Mnod_6789	aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
Mnod_1585	aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
Mnod_0239	aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
Mnod_2908	aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]
Mnod_2684	coenzyme A transferase; K01026 propionate CoA-transferase [EC:2.8.3.1] [KO:K01026] [EC:2.8.3.1]
Mnod_7392	FMN-dependent alpha-hydroxy acid dehydrogenase; K00101 L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3] [KO:K00101] [EC:1.1.2.3]
Mnod_0414	thiamine pyrophosphate protein TPP binding domain-containing protein; K00156 pyruvate dehydrogenase (quinone) [EC:1.2.5.1] [KO:K00156] [EC:1.2.5.1]
Mnod_3071	D-lactate dehydrogenase; K03777 D-lactate dehydrogenase [EC:1.1.1.28] [KO:K03777] [EC:1.1.1.28]
Mnod_0518	FAD linked oxidase domain-containing protein; K00102 D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] [KO:K00102] [EC:1.1.2.4]
Mnod_1458	FAD linked oxidase domain-containing protein; K00102 D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] [KO:K00102] [EC:1.1.2.4]
Mnod_5474	glyoxalase/bleomycin resistance protein/dioxygenase; K01759 lactoylglutathione lyase [EC:4.4.1.5] [KO:K01759] [EC:4.4.1.5]
Mnod_5815	glyoxalase/bleomycin resistance protein/dioxygenase; K01759 lactoylglutathione lyase [EC:4.4.1.5] [KO:K01759] [EC:4.4.1.5]
Mnod_0448	hydroxyacylglutathione hydrolase; K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6] [KO:K01069] [EC:3.1.2.6]
Mnod_1511	NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; K12972 gyoxylate/hydroxypyruvate reductase A [EC:1.1.1.79 1.1.1.81] [KO:K12972] [EC:1.1.1.81 1.1.1.79]
Mnod_2906	NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; K12972 gyoxylate/hydroxypyruvate reductase A [EC:1.1.1.79 1.1.1.81] [KO:K12972] [EC:1.1.1.81 1.1.1.79]
Mnod_2328	malic enzyme; K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] [KO:K00029] [EC:1.1.1.40]
Mnod_7102	malic enzyme; K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] [KO:K00029] [EC:1.1.1.40]
Mnod_2174	malic enzyme; K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] [KO:K00029] [EC:1.1.1.40]
Mnod_1123	malate dehydrogenase; K00024 malate dehydrogenase [EC:1.1.1.37] [KO:K00024] [EC:1.1.1.37]
Mnod_4503	phosphoenolpyruvate carboxylase; K01595 phosphoenolpyruvate carboxylase [EC:4.1.1.31] [KO:K01595] [EC:4.1.1.31]
Mnod_7118	phosphoenolpyruvate carboxylase; K01595 phosphoenolpyruvate carboxylase [EC:4.1.1.31] [KO:K01595] [EC:4.1.1.31]
Mnod_5431	phosphoenolpyruvate carboxykinase; K01610 phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] [KO:K01610] [EC:4.1.1.49]
Mnod_2849	pyruvate phosphate dikinase; K01006 pyruvate,orthophosphate dikinase [EC:2.7.9.1] [KO:K01006] [EC:2.7.9.1]
Mnod_0188	malate synthase G; K01638 malate synthase [EC:2.3.3.9] [KO:K01638] [EC:2.3.3.9]
Mnod_6744	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_3980	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_4781	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_7471	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_5240	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_3077	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_5443	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_5917	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
Mnod_0953	2-isopropylmalate synthase; K01649 2-isopropylmalate synthase [EC:2.3.3.13] [KO:K01649] [EC:2.3.3.13]

Compound

C00022	Pyruvate
C00024	Acetyl-CoA
C00033	Acetate
C00036	Oxaloacetate
C00058	Formate
C00068	Thiamin diphosphate
C00074	Phosphoenolpyruvate
C00083	Malonyl-CoA
C00084	Acetaldehyde
C00111	Glycerone phosphate
C00149	(S)-Malate
C00186	(S)-Lactate
C00227	Acetyl phosphate
C00256	(R)-Lactate
C00332	Acetoacetyl-CoA
C00424	(S)-Lactaldehyde
C00546	Methylglyoxal
C00583	Propane-1,2-diol
C00937	(R)-Lactaldehyde
C01251	(R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488	(R)-2-Ethylmalate
C02504	alpha-Isopropylmalate
C03248	Acetylenedicarboxylate
C03451	(R)-S-Lactoylglutathione
C03981	2-Hydroxyethylenedicarboxylate
C05125	2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993	Acetyl adenylate
C05994	2-Propylmalate
C05999	Lactaldehyde
C15972	Enzyme N6-(lipoyl)lysine
C15973	Enzyme N6-(dihydrolipoyl)lysine
C16255	[Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine

KO pathway

ko00620

All links

Pathway (2)   
   KEGG MODULE (1)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (67)   
   KEGG GENES (67)   
All databases (70)   

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