KEGG PATHWAY: mpa00230

PATHWAY: mpa00230

Entry

mpa00230 Pathway

Name

Purine metabolism - Mycobacterium avium subsp. paratuberculosis K-10

Class

Metabolism; Nucleotide metabolism

Pathway map

mpa00230

Purine metabolism

Module

mpa_M00005	PRPP biosynthesis, ribose 5P => PRPP [PATH:mpa00230]
mpa_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:mpa00230]
mpa_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mpa00230]
mpa_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:mpa00230]
mpa_M00546	Purine degradation, xanthine => urea [PATH:mpa00230]

Other DBs

BSID:

15279

GO:

0042278

Organism

Mycobacterium avium subsp. paratuberculosis K-10 [GN:mpa]

Gene

MAP1407	hypothetical protein; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
MAP3146c	pgmA; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
MAP0983c	prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MAP0638	purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MAP0606	purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MAP0902	purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MAP3871	purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:2.1.2.2]
MAP0626	purQ; phosphoribosylformylglycinamidine synthase I [KO:K01952] [EC:6.3.5.3]
MAP0635	purL; phosphoribosylformylglycinamidine synthase II [KO:K01952] [EC:6.3.5.3]
MAP0625	phosphoribosylformylglycinamidine synthase subunit PurS; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
MAP0639	purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
MAP3394c	purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
MAP3393c	purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
MAP0614	hemH; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MAP0611	purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MAP0903	purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
MAP1046	apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
MAP3429	deoD; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MAP0439	hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MAP1556c	guaB1; inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MAP4278	guaB2; inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MAP4279	guaB3; inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
MAP2268c	ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MAP2420c	deoxyribonucleotide triphosphate pyrophosphatase; K02428 dITP/XTP pyrophosphatase [EC:3.6.1.19] [KO:K02428] [EC:3.6.1.19]
MAP0988	nucleoside triphosphate pyrophosphohydrolase; K02428 dITP/XTP pyrophosphatase [EC:3.6.1.19] [KO:K02428] [EC:3.6.1.19]
MAP3489c	guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
MAP1123	gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MAP1310	pykA; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
MAP3100c	nrdE; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MAP3095c	nrdF; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MAP3672	nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
MAP2132c	dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
MAP4233	rpoA; DNA-directed RNA polymerase subunit alpha [KO:K03040] [EC:2.7.7.6]
MAP4130	rpoB; DNA-directed RNA polymerase subunit beta [KO:K03043] [EC:2.7.7.6]
MAP4131	rpoC; DNA-directed RNA polymerase subunit beta' [KO:K03046] [EC:2.7.7.6]
MAP1124	DNA-directed RNA polymerase subunit omega; K03060 DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] [KO:K03060] [EC:2.7.7.6]
MAP1322	polA; DNA polymerase I [KO:K02335] [EC:2.7.7.7]
MAP1257	dnaE; DNA polymerase III subunit alpha [KO:K02337] [EC:2.7.7.7]
MAP0002	dnaN; DNA polymerase III subunit beta [KO:K02338] [EC:2.7.7.7]
MAP0322c	dnaZX; DNA polymerase III subunits gamma and tau [KO:K02343] [EC:2.7.7.7]
MAP2225c	hypothetical protein; K02340 DNA polymerase III subunit delta [EC:2.7.7.7] [KO:K02340] [EC:2.7.7.7]
MAP0427	DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta' [EC:2.7.7.7] [KO:K02341] [EC:2.7.7.7]
MAP0313c	dnaQ; DNA polymerase III subunit epsilon [KO:K02342] [EC:2.7.7.7]
MAP1930	hypothetical protein; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
MAP0993	hypothetical protein; K01524 exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] [KO:K01524] [EC:3.6.1.40 3.6.1.11]
MAP3987	hypothetical protein; K01524 exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] [KO:K01524] [EC:3.6.1.40 3.6.1.11]
MAP1047	relA; RelA [KO:K00951] [EC:2.7.6.5]
MAP1318c	hypothetical protein; K01768 adenylate cyclase [EC:4.6.1.1] [KO:K01768] [EC:4.6.1.1]
MAP2440	hypothetical protein; K01768 adenylate cyclase [EC:4.6.1.1] [KO:K01768] [EC:4.6.1.1]
MAP2507c	hypothetical protein; K01768 adenylate cyclase [EC:4.6.1.1] [KO:K01768] [EC:4.6.1.1]
MAP0426c	hypothetical protein; K01768 adenylate cyclase [EC:4.6.1.1] [KO:K01768] [EC:4.6.1.1]
MAP3869	purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
MAP1942c	cbhK; CbhK [KO:K00856] [EC:2.7.1.20]
MAP3438c	add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
MAP4199	adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
MAP2891c	gpsI; polynucleotide phosphorylase/polyadenylase [KO:K00962] [EC:2.7.7.8]
MAP2484c	cysN; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein [KO:K00955] [EC:2.7.1.25 2.7.7.4]
MAP2599c	hypothetical protein; K00860 adenylylsulfate kinase [EC:2.7.1.25] [KO:K00860] [EC:2.7.1.25]
MAP2485c	cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
MAP2598c	sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
MAP4203	hypothetical protein; K16839 FAD-dependent urate hydroxylase [EC:1.14.13.113] [KO:K16839] [EC:1.14.13.113]

Compound

C00002	ATP
C00008	ADP
C00011	CO2
C00014	NH3
C00020	AMP
C00035	GDP
C00037	Glycine
C00039	DNA
C00044	GTP
C00046	RNA
C00048	Glyoxylate
C00053	3'-Phosphoadenylyl sulfate
C00054	Adenosine 3',5'-bisphosphate
C00059	Sulfate
C00064	L-Glutamine
C00081	ITP
C00086	Urea
C00104	IDP
C00117	D-Ribose 5-phosphate
C00119	5-Phospho-alpha-D-ribose 1-diphosphate
C00130	IMP
C00131	dATP
C00144	GMP
C00147	Adenine
C00169	Carbamoyl phosphate
C00206	dADP
C00212	Adenosine
C00224	Adenylyl sulfate
C00242	Guanine
C00262	Hypoxanthine
C00286	dGTP
C00294	Inosine
C00301	ADP-ribose
C00330	Deoxyguanosine
C00360	dAMP
C00361	dGDP
C00362	dGMP
C00366	Urate
C00385	Xanthine
C00387	Guanosine
C00499	Allantoate
C00559	Deoxyadenosine
C00575	3',5'-Cyclic AMP
C00603	(-)-Ureidoglycolate
C00620	alpha-D-Ribose 1-phosphate
C00655	Xanthosine 5'-phosphate
C00700	XTP
C00802	Oxalureate
C00942	3',5'-Cyclic GMP
C01228	Guanosine 3',5'-bis(diphosphate)
C01260	P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261	P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344	dIDP
C01345	dITP
C01367	3'-AMP
C01762	Xanthosine
C02091	(S)-Ureidoglycine
C02348	(R)(-)-Allantoin
C02350	(S)(+)-Allantoin
C02353	2',3'-Cyclic AMP
C02718	N-Formiminoglycine
C03090	5-Phosphoribosylamine
C03373	Aminoimidazole ribotide
C03483	Adenosine tetraphosphate
C03614	Inosine 5'-tetraphosphate
C03794	N6-(1,2-Dicarboxyethyl)-AMP
C03838	5'-Phosphoribosylglycinamide
C04051	5-Amino-4-imidazolecarboxyamide
C04376	5'-Phosphoribosyl-N-formylglycinamide
C04392	P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494	Guanosine 3'-diphosphate 5'-triphosphate
C04640	2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677	1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734	1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751	1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823	1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239	5-Aminoimidazole
C05512	Deoxyinosine
C05513	Urate-3-ribonucleoside
C05515	5-Ureido-4-imidazole carboxylate
C05516	5-Amino-4-imidazole carboxylate
C05993	Acetyl adenylate
C06193	Guanosine 3'-phosphate
C06194	2',3'-Cyclic GMP
C06195	Imidazolone
C06196	2'-Deoxyinosine 5'-phosphate
C06197	P1,P3-Bis(5'-adenosyl) triphosphate
C06433	5'-Benzoylphosphoadenosine
C06435	5'-Butyrylphosphoinosine
C11821	5-Hydroxyisourate
C12248	5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667	5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole

Reference

PMID:10601204

Authors

Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.

Title

Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Journal

J Bacteriol 181:7479-84 (1999)

Reference

PMID:10986234

Authors

Xi H, Schneider BL, Reitzer L.

Title

Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.

Journal

J Bacteriol 182:5332-41 (2000)

KO pathway

ko00230

All links

Pathway (5)   
   KEGG MODULE (4)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (61)   
   KEGG GENES (61)   
All databases (67)   

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