KEGG   PATHWAY: mse00630
Entry
mse00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Metallosphaera sedula DSM 5348
Class
Metabolism; Carbohydrate metabolism
Pathway map
mse00630  Glyoxylate and dicarboxylate metabolism
mse00630

Module
mse_M00621  Glycine cleavage system [PATH:mse00630]
mse_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mse00630]
Other DBs
GO: 0046487 0043648
Organism
Metallosphaera sedula DSM 5348 [GN:mse]
Gene
Msed_1353  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Msed_1291  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Msed_0267  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Msed_1042  malate synthase [KO:K01638] [EC:2.3.3.9]
Msed_0455  malate dehydrogenase (NAD) [KO:K00024] [EC:1.1.1.37]
Msed_1522  citrate synthase [KO:K01647] [EC:2.3.3.1]
Msed_0281  citrate synthase [KO:K01647] [EC:2.3.3.1]
Msed_1467  aconitase [KO:K01681] [EC:4.2.1.3]
Msed_0656  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Msed_0270  Acetyl-CoA acetyltransferase-like protein [KO:K00626] [EC:2.3.1.9]
Msed_0271  Acetyl-CoA acetyltransferase-like protein [KO:K00626] [EC:2.3.1.9]
Msed_0386  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Msed_0396  Thiolase [KO:K00626] [EC:2.3.1.9]
Msed_1290  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Msed_1647  Acetyl-CoA acetyltransferase-like protein [KO:K00626] [EC:2.3.1.9]
Msed_0639  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Msed_1216  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
Msed_0147  biotin carboxylase [KO:K01964] [EC:6.4.1.2 6.4.1.3]
Msed_1375  acetyl-CoA carboxylase carboxyltransferase subunit alpha / acetyl-CoA carboxylase carboxyltransferase subunit beta / propionyl-CoA carboxylase carboxyltransferase subunit [KO:K15036] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Msed_0148  biotin carboxyl carrier protein [KO:K15037]
Msed_2055  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
Msed_0638  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
Msed_0553  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Msed_0436  D-lactate dehydrogenase [KO:K00104] [EC:1.1.99.14]
Msed_1118  D-lactate dehydrogenase [KO:K00104] [EC:1.1.99.14]
Msed_0552  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Msed_0554  protein of unknown function DUF224, cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Msed_0256  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
Msed_2130  phosphoglycolate phosphatase [KO:K22223] [EC:3.1.3.18]
Msed_1612  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Msed_0602  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Msed_1650  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Msed_1664  glycine dehydrogenase (decarboxylating) alpha subunit [KO:K00282] [EC:1.4.4.2]
Msed_1665  glycine dehydrogenase (decarboxylating) beta subunit [KO:K00283] [EC:1.4.4.2]
Msed_1663  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Msed_1091  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Msed_1551  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Msed_2009  pyridine nucleotide-disulfide oxidoreductase dimerization region [KO:K00382] [EC:1.8.1.4]
Msed_1971  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Msed_1481  glycine cleavage system H protein [KO:K02437]
Msed_1662  glycine cleavage system H protein [KO:K02437]
Msed_1570  glycine cleavage system H protein [KO:K02437]
Msed_2013  glycerate 2-kinase [KO:K11529] [EC:2.7.1.165]
Msed_1318  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Msed_1457  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mse00010  Glycolysis / Gluconeogenesis
mse00020  Citrate cycle (TCA cycle)
mse00030  Pentose phosphate pathway
mse00071  Fatty acid degradation
mse00230  Purine metabolism
mse00250  Alanine, aspartate and glutamate metabolism
mse00260  Glycine, serine and threonine metabolism
mse00620  Pyruvate metabolism
mse00750  Vitamin B6 metabolism
mse00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (45)   
   KEGG GENES (45)   
All databases (46)   

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