KEGG   PATHWAY: msl00630
Entry
msl00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Methylocella silvestris
Class
Metabolism; Carbohydrate metabolism
Pathway map
msl00630  Glyoxylate and dicarboxylate metabolism
msl00630

Module
msl_M00012  Glyoxylate cycle [PATH:msl00630]
msl_M00621  Glycine cleavage system [PATH:msl00630]
msl_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:msl00630]
Other DBs
GO: 0046487 0043648
Organism
Methylocella silvestris [GN:msl]
Gene
Msil_3157  isocitrate lyase and phosphorylmutase [KO:K01637] [EC:4.1.3.1]
Msil_1226  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Msil_1325  malate synthase G [KO:K01638] [EC:2.3.3.9]
Msil_2501  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
Msil_1681  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Msil_3509  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
Msil_1717  succinyl-CoA synthetase, alpha subunit [KO:K08692] [EC:6.2.1.9]
Msil_1716  succinyl-CoA synthetase, beta subunit [KO:K14067] [EC:6.2.1.9]
Msil_2996  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Msil_2997  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Msil_2934  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Msil_1719  Citrate (pro-3S)-lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Msil_3786  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K01965] [EC:6.4.1.3]
Msil_3787  Propionyl-CoA carboxylase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Msil_3784  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Msil_3785  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Msil_1695  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Msil_2541  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Msil_2540  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Msil_3597  Catalase [KO:K03781] [EC:1.11.1.6]
Msil_2465  Catalase [KO:K03781] [EC:1.11.1.6]
Msil_2091  Catalase domain protein [KO:K03781] [EC:1.11.1.6]
Msil_2485  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
Msil_1713  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00018] [EC:1.1.1.29]
Msil_2100  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
Msil_3438  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Msil_0118  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
Msil_1195  Ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
Msil_1196  Ribulose-bisphosphate carboxylase [KO:K01602] [EC:4.1.1.39]
Msil_1714  aminotransferase class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Msil_3400  Serine--glyoxylate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Msil_0426  Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
Msil_0427  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Msil_2110  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Msil_1215  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
Msil_1214  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
Msil_3603  glycine cleavage T protein (aminomethyl transferase) [KO:K00605] [EC:2.1.2.10]
Msil_3605  glycine cleavage T protein (aminomethyl transferase) [KO:K00605] [EC:2.1.2.10]
Msil_1217  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Msil_0522  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Msil_2506  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Msil_1216  glycine cleavage system H protein [KO:K02437]
Msil_1715  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Msil_1123  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Msil_0110  bicupin, oxalate decarboxylase family [KO:K01569] [EC:4.1.1.2]
Msil_2183  bicupin, oxalate decarboxylase family [KO:K01569] [EC:4.1.1.2]
Msil_2678  bicupin, oxalate decarboxylase family [KO:K01569] [EC:4.1.1.2]
Msil_0722  bicupin, oxalate decarboxylase family [KO:K01569] [EC:4.1.1.2]
Msil_2451  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00122] [EC:1.17.1.9]
Msil_3658  putative NAD-dependent formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
Msil_3325  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Msil_3656  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Msil_3326  formate dehydrogenase, beta subunit [KO:K00124]
Msil_3655  NADH dehydrogenase (quinone) [KO:K00124]
Msil_3327  formate dehydrogenase, gamma subunit [KO:K00127]
Msil_3654  NADH dehydrogenase (ubiquinone) 24 kDa subunit [KO:K00127]
Msil_0106  AMP-dependent synthetase and ligase [KO:K22133] [EC:6.2.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
msl00010  Glycolysis / Gluconeogenesis
msl00020  Citrate cycle (TCA cycle)
msl00030  Pentose phosphate pathway
msl00053  Ascorbate and aldarate metabolism
msl00071  Fatty acid degradation
msl00230  Purine metabolism
msl00250  Alanine, aspartate and glutamate metabolism
msl00260  Glycine, serine and threonine metabolism
msl00620  Pyruvate metabolism
msl00710  Carbon fixation in photosynthetic organisms
msl00750  Vitamin B6 metabolism
msl00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (57)   
   KEGG GENES (57)   
All databases (58)   

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