KEGG   PATHWAY: mtc00280
Entry
mtc00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Mycobacterium tuberculosis CDC1551
Class
Metabolism; Amino acid metabolism
Pathway map
mtc00280  Valine, leucine and isoleucine degradation
mtc00280

Module
mtc_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mtc00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Mycobacterium tuberculosis CDC1551 [GN:mtc]
Gene
MT2266  ilvE; branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
MT2572  2-oxoisovalerate dehydrogenase E1 component, alpha subunit, putative [KO:K00166] [EC:1.2.4.4]
MT2571  2-oxoisovalerate dehydrogenase E1 component, beta subunit, putative [KO:K00167] [EC:1.2.4.4]
MT2570  2-oxoisovalerate dehydrogenase E2 component, dihydrolipoamide acetyltransferase, putative [KO:K09699] [EC:2.3.1.168]
MT0478  lpdA-1; alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
MT1003  acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
MT3227  acyl-CoA dehydrogenase [KO:K00249] [EC:1.3.8.7]
MT0139  acyl-CoA dehydrogenase, putative [KO:K00249] [EC:1.3.8.7]
MT0163  acyl-CoA dehydrogenase, putative [KO:K00249] [EC:1.3.8.7]
MT0241  acyl-CoA dehydrogenase, putative [KO:K00249] [EC:1.3.8.7]
MT1719  acyl-CoA dehydrogenase, putative [KO:K00249] [EC:1.3.8.7]
MT2575  acyl-CoA dehydrogenase [KO:K11410] [EC:1.3.8.5]
MT1100  enoyl-CoA hydratase/isomerase family protein [KO:K01692] [EC:4.2.1.17]
MT2560  enoyl-CoA hydratase/isomerase family protein [KO:K01692] [EC:4.2.1.17]
MT1518  enoyl-CoA hydratase/isomerase family protein [KO:K01692] [EC:4.2.1.17]
MT3124  enoyl-CoA hydratase/isomerase family protein [KO:K01692] [EC:4.2.1.17]
MT0883  fatty oxidation complex, alpha subunit [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
MT2860  nonspecific lipid-transfer protein [KO:K00632] [EC:2.3.1.16]
MT1001  bccA-1; acetyl/propionyl-CoA carboxylase, alpha subunit [KO:K01965] [EC:6.4.1.3]
MT3384  bccA-3; acetyl/propionyl-CoA carboxylase, alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MT2307  pccB-2; propionyl-CoA carboxylase, beta subunit [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MT1364  4-hydroxyphenylpyruvate dioxygenase C terminal domain containing protein [KO:K05606] [EC:5.1.99.1]
MT1540  mutB; methylmalonyl-CoA mutase, alpha subunit [KO:K01847] [EC:5.4.99.2]
MT1539  mutA; methylmalonyl-CoA mutase, beta subunit [KO:K01847] [EC:5.4.99.2]
MT0775  mmsB; 3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
MT0777  mmsA; methylmalonic acid semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
MT0792  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
MT0155  aldehyde dehydrogenase, class 3 [KO:K00128] [EC:1.2.1.3]
MT0233  aldehyde dehydrogenase family protein [KO:K00128] [EC:1.2.1.3]
MT2666  gabT; 4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
MT2576  bccA-2; acetyl/propionyl-CoA carboxylase, alpha subunit [KO:K01968] [EC:6.4.1.4]
MT2577  pccB-3; propionyl-CoA carboxylase, beta subunit [KO:K01969] [EC:6.4.1.4]
MT2579  scoA; succinyl-CoA:3-ketoacid-coenzyme A transferase, A subunit [KO:K01028] [EC:2.8.3.5]
MT2578  scoB; succinyl-CoA:3-ketoacid-coenzyme A transferase, B subunit [KO:K01029] [EC:2.8.3.5]
MT1365  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MT0882  thiolase [KO:K00626] [EC:2.3.1.9]
MT0939  thiolase [KO:K00626] [EC:2.3.1.9]
MT3623  nonspecific lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
MT3650  thiolase [KO:K00626] [EC:2.3.1.9]
MT0257  thiolase [KO:K00626] [EC:2.3.1.9]
MT1104  thiolase [KO:K00626] [EC:2.3.1.9]
MT3660  thiolase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
mtc00020  Citrate cycle (TCA cycle)
mtc00240  Pyrimidine metabolism
mtc00290  Valine, leucine and isoleucine biosynthesis
mtc00640  Propanoate metabolism
mtc00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG GENES (42)   
All databases (43)   

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