KEGG PATHWAY: mtl00630

PATHWAY: mtl00630

Entry

mtl00630 Pathway

Name

Glyoxylate and dicarboxylate metabolism - Mycobacterium tuberculosis CCDC5180

Class

Metabolism; Carbohydrate metabolism

Pathway map

mtl00630

Glyoxylate and dicarboxylate metabolism

Module

mtl_M00012	Glyoxylate cycle [PATH:mtl00630]
mtl_M00373	Ethylmalonyl pathway [PATH:mtl00630]
mtl_M00532	Photorespiration [PATH:mtl00630]

Organism

Mycobacterium tuberculosis CCDC5180 [GN:mtl]

Gene

CCDC5180_0431	isocitrate lyase; K01637 isocitrate lyase [EC:4.1.3.1] [KO:K01637] [EC:4.1.3.1]
CCDC5180_1748	isocitrate lyase; K01637 isocitrate lyase [EC:4.1.3.1] [KO:K01637] [EC:4.1.3.1]
CCDC5180_1674	malate synthase G; K01638 malate synthase [EC:2.3.3.9] [KO:K01638] [EC:2.3.3.9]
CCDC5180_1139	malate dehydrogenase; K00024 malate dehydrogenase [EC:1.1.1.37] [KO:K00024] [EC:1.1.1.37]
CCDC5180_0814	citrate synthase 2; K01647 citrate synthase [EC:2.3.3.1] [KO:K01647] [EC:2.3.3.1]
CCDC5180_0821	citrate synthase I gltA2; K01647 citrate synthase [EC:2.3.3.1] [KO:K01647] [EC:2.3.3.1]
CCDC5180_1036	citrate synthase; K01647 citrate synthase [EC:2.3.3.1] [KO:K01647] [EC:2.3.3.1]
CCDC5180_1363	aconitate hydratase; K01681 aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-] [KO:K01681] [EC:4.2.1.- 4.2.1.3]
CCDC5180_0836	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_0984	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_0225	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_3216	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_1217	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_1702	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_0787	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_3239	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_3249	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
CCDC5180_0889	acetyl-/propionyl-CoA carboxylase alpha subunit accA2; K01965 propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] [KO:K01965] [EC:6.4.1.3]
CCDC5180_2990	propionyl-CoA carboxylase subunit beta; K01966 propionyl-CoA carboxylase beta chain [EC:6.4.1.3] [KO:K01966] [EC:6.4.1.3]
CCDC5180_1380	methylmalonyl-CoA mutase small subunit mutA; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]
CCDC5180_1381	methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]
CCDC5180_2591	glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
CCDC5180_1713	glutamine synthetase glnA3; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
CCDC5180_2029	glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
CCDC5180_2031	glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
CCDC5180_1001	serine hydroxymethyltransferase; K00600 glycine hydroxymethyltransferase [EC:2.1.2.1] [KO:K00600] [EC:2.1.2.1]
CCDC5180_0064	serine hydroxymethyltransferase; K00600 glycine hydroxymethyltransferase [EC:2.1.2.1] [KO:K00600] [EC:2.1.2.1]
CCDC5180_1663	glycine cleavage system protein H; K02437 glycine cleavage system H protein [KO:K02437]
CCDC5180_2013	hypothetical protein; K00865 glycerate kinase [EC:2.7.1.31] [KO:K00865] [EC:2.7.1.31]
CCDC5180_2686	formyltetrahydrofolate deformylase; K01433 formyltetrahydrofolate deformylase [EC:3.5.1.10] [KO:K01433] [EC:3.5.1.10]
CCDC5180_0103	oxalyl-CoA decarboxylase oxcA; K01577 oxalyl-CoA decarboxylase [EC:4.1.1.8] [KO:K01577] [EC:4.1.1.8]

Compound

C00007	Oxygen
C00011	CO2
C00014	NH3
C00022	Pyruvate
C00024	Acetyl-CoA
C00025	L-Glutamate
C00026	2-Oxoglutarate
C00027	Hydrogen peroxide
C00036	Oxaloacetate
C00037	Glycine
C00042	Succinate
C00048	Glyoxylate
C00058	Formate
C00064	L-Glutamine
C00065	L-Serine
C00091	Succinyl-CoA
C00100	Propanoyl-CoA
C00136	Butanoyl-CoA
C00149	(S)-Malate
C00158	Citrate
C00160	Glycolate
C00168	Hydroxypyruvate
C00197	3-Phospho-D-glycerate
C00209	Oxalate
C00258	D-Glycerate
C00266	Glycolaldehyde
C00311	Isocitrate
C00313	Oxalyl-CoA
C00332	Acetoacetyl-CoA
C00417	cis-Aconitate
C00552	meso-Tartaric acid
C00683	(S)-Methylmalonyl-CoA
C00798	Formyl-CoA
C00877	Crotonoyl-CoA
C00888	Pentanoyl-CoA
C00898	(R,R)-Tartaric acid
C00975	Dihydroxyfumarate
C00988	2-Phosphoglycolate
C01127	4-Hydroxy-2-oxoglutarate
C01146	2-Hydroxy-3-oxopropanoate
C01182	D-Ribulose 1,5-bisphosphate
C01213	(R)-Methylmalonyl-CoA
C01380	Ethylene glycol
C01989	3-Ethylmalate
C01990	3-Oxalomalate
C02123	3-Propylmalate
C02405	Formyl phosphate
C03217	2-Hydroxy-3-oxoadipate
C03459	2-Hydroxy-3-oxosuccinate
C03548	trans-2,3-Epoxysuccinate
C03561	(R)-3-Hydroxybutanoyl-CoA
C04348	(3S)-3-Carboxy-3-hydroxypropanoyl-CoA
C06027	L-erythro-3-Methylmalyl-CoA
C06028	Mesaconyl-CoA
C06049	N-Formylderivatives
C18026	(2S)-Ethylmalonyl-CoA
C18324	(2S)-Methylsuccinyl-CoA
C20238	(2R)-Ethylmalonyl-CoA

Reference

PMID:10978349 (EC5.3.1.22)

Authors

Njau RK, Herndon CA, Hawes JW.

Title

Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilusinfluenzae.

Journal

J Biol Chem 275:38780-6 (2000)

Reference

PMID:18065535

Authors

Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G

Title

Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.

Journal

J Bacteriol 190:1366-74 (2008)

Reference

PMID:18819910

Authors

Erb TJ, Retey J, Fuchs G, Alber BE

Title

Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.

Journal

J Biol Chem 283:32283-93 (2008)

KO pathway

ko00630

All links

Pathway (2)   
   KEGG MODULE (1)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG GENES (31)   
All databases (34)   

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