KEGG   PATHWAY: neu00230
Entry
neu00230                    Pathway                                
Name
Purine metabolism - Nitrosomonas europaea
Class
Metabolism; Nucleotide metabolism
Pathway map
neu00230  Purine metabolism
neu00230

Module
neu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:neu00230]
neu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:neu00230]
neu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:neu00230]
neu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:neu00230]
neu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:neu00230]
Other DBs
GO: 0006163 0042278
Organism
Nitrosomonas europaea [GN:neu]
Gene
NE2470  NUDIX hydrolase:Conserved hypothetical protein 52 [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NE1895  Phosphoglucomutase and phosphomannomutase family [KO:K15778] [EC:5.4.2.8 5.4.2.2]
NE1826  Phosphoribosyl transferase [KO:K00948] [EC:2.7.6.1]
NE0699  purF; Glutamine amidotransferase class-II:Phosphoribosyl transferase [KO:K00764] [EC:2.4.2.14]
NE0877  purD; Phosphoribosylglycinamide synthetase [KO:K01945] [EC:6.3.4.13]
NE0087  purN; purN; phosphoribosylglycinamide formyltransferase protein [KO:K11175] [EC:2.1.2.2]
NE0019  purL; AIR synthase related protein [KO:K01952] [EC:6.3.5.3]
NE0088  purM; purM; phosphoribosylformylglycinamidine cyclo-ligase (airS) protein [KO:K01933] [EC:6.3.3.1]
NE0867  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit; ATP-grasp domain [KO:K01589] [EC:6.3.4.18]
NE0868  purE; purE; phosphoribosylaminoimidazole carboxylase catalytic subunit protein [KO:K01588] [EC:5.4.99.18]
NE0866  purC; SAICAR synthetase [KO:K01923] [EC:6.3.2.6]
NE1951  Fumarate lyase:Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
NE0876  purH; probable phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclodydrolase transmembrane protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
NE0181  apt; Phosphoribosyl transferase [KO:K00759] [EC:2.4.2.7]
NE0950  surE; Survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
NE1654  DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
NE0095  guaB; guaB; inosine-5'-monophosphate dehydrogenase oxidoreductase protein [KO:K00088] [EC:1.1.1.205]
NE0144  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
NE0277  Ham1 family [KO:K01519] [EC:3.6.1.66]
NE0094  guaA; guaA; GMP synthetase [KO:K01951] [EC:6.3.5.2]
NE2254  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
NE2423  nrdA; Ribonucleotide reductase large subunit [KO:K00525] [EC:1.17.4.1]
NE2422  nrdB; Ribonucleotide reductase [KO:K00526] [EC:1.17.4.1]
NE1982  dgt; HD domain:Metal dependent phosphohydrolase HD domain [KO:K01129] [EC:3.1.5.1]
NE0368  spoT; spoT; bifunctional enzyme (p)ppgpp synthetase II and guanosine-3',5'-bisdiphosphate 3'-pyro [KO:K01139] [EC:2.7.6.5 3.1.7.2]
NE1745  ppx; Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
NE1299  Guanylate cyclase [KO:K01768] [EC:4.6.1.1]
NE1496  conserved hypothetical protein [KO:K01768] [EC:4.6.1.1]
NE1847  Guanylate cyclase [KO:K01768] [EC:4.6.1.1]
NE1281  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
NE0611  PfkB family of carbohydrate kinases [KO:K00856] [EC:2.7.1.20]
NE1933  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
NE0613  bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
NE0857  cysN; GTP-binding elongation factor:Elongation factor Tu domain 2 [KO:K00956] [EC:2.7.7.4]
NE0856  cysD; Phosphoadenosine phosphosulfate reductase [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
neu00030  Pentose phosphate pathway
neu00220  Arginine biosynthesis
neu00250  Alanine, aspartate and glutamate metabolism
neu00260  Glycine, serine and threonine metabolism
neu00340  Histidine metabolism
neu00630  Glyoxylate and dicarboxylate metabolism
neu00730  Thiamine metabolism
neu00740  Riboflavin metabolism
neu00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG GENES (35)   
All databases (36)   

Download RDF
DBGET integrated database retrieval system