KEGG   PATHWAY: nla00290
Entry
nla00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Neisseria lactamica
Class
Metabolism; Amino acid metabolism
Pathway map
nla00290  Valine, leucine and isoleucine biosynthesis
nla00290

Module
nla_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:nla00290]
nla_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:nla00290]
nla_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:nla00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Neisseria lactamica [GN:nla]
Gene
NLA_13600  ilvA; putative threonine dehydratase biosynthetic [KO:K01754] [EC:4.3.1.19]
NLA_10810  leuC; putative 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
NLA_10830  leuD; putative 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
NLA_10860  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
NLA_7060  ilvI; acetolactate synthase isozyme III large subunit [KO:K01652] [EC:2.2.1.6]
NLA_7070  ilvH; acetolactate synthase isozyme III small subunit [KO:K01653] [EC:2.2.1.6]
NLA_7090  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
NLA_9870  ilvD; putative dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
NLA_3940  ilvE; putative branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
NLA_17610  avtA; putative valine--pyruvate aminotransferase [KO:K00835] [EC:2.6.1.66]
NLA_7990  probable aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
NLA_9550  leuA; putative 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
nla00260  Glycine, serine and threonine metabolism
nla00280  Valine, leucine and isoleucine degradation
nla00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG GENES (12)   
All databases (13)   

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