KEGG   PATHWAY: nmn00290
Entry
nmn00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Neisseria meningitidis 053442 (serogroup C)
Class
Metabolism; Amino acid metabolism
Pathway map
nmn00290  Valine, leucine and isoleucine biosynthesis
nmn00290

Module
nmn_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:nmn00290]
nmn_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:nmn00290]
nmn_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:nmn00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Neisseria meningitidis 053442 (serogroup C) [GN:nmn]
Gene
NMCC_0840  ilvA; threonine dehydratase biosynthetic [KO:K01754] [EC:4.3.1.19]
NMCC_1159  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
NMCC_1161  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
NMCC_1164  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
NMCC_1480  ilvI; acetolactate synthase isozyme III large subunit [KO:K01652] [EC:2.2.1.6]
NMCC_1479  ilvH; acetolactate synthase isozyme III small subunit [KO:K01653] [EC:2.2.1.6]
NMCC_1477  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
NMCC_1068  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
NMCC_1806  ilvE; branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
NMCC_0402  avtA; valine--pyruvate aminotransferase [KO:K00835] [EC:2.6.1.66]
NMCC_1385  aminotransferase, class I [KO:K14260] [EC:2.6.1.66 2.6.1.2]
NMCC_0988  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
nmn00260  Glycine, serine and threonine metabolism
nmn00280  Valine, leucine and isoleucine degradation
nmn00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG GENES (12)   
All databases (13)   

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