KEGG   PATHWAY: plt02010Help
plt02010                    Pathway                                

ABC transporters - Chlorobium luteolum
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
plt02010  ABC transporters

Ortholog table
plt_M00185  Sulfate transport system [PATH:plt02010]
plt_M00189  Molybdate transport system [PATH:plt02010]
plt_M00222  Phosphate transport system [PATH:plt02010]
plt_M00239  Peptides/nickel transport system [PATH:plt02010]
plt_M00240  Iron complex transport system [PATH:plt02010]
plt_M00242  Zinc transport system [PATH:plt02010]
plt_M00245  Cobalt/nickel transport system [PATH:plt02010]
plt_M00246  Nickel transport system [PATH:plt02010]
plt_M00255  Lipoprotein-releasing system [PATH:plt02010]
plt_M00256  Cell division transport system [PATH:plt02010]
plt_M00320  Lipopolysaccharide export system [PATH:plt02010]
Other DBs
BSID: 28310
GO: 0043190 0043191 0043192
TC: 3.A.1
Chlorobium luteolum [GN:plt]
Plut_1552  Thiosulphate-binding protein [KO:K02048]
Plut_1553  Sulfate ABC transporter, permease protein CysT [KO:K02046]
Plut_1554  Sulfate ABC transporter, permease protein CysW [KO:K02047]
Plut_1555  Sulphate transport system permease protein 1 [KO:K02045] [EC:]
Plut_1708  Molybdenum ABC transporter, periplasmic binding protein [KO:K02020]
Plut_1541  Molybdenum ABC transporter, periplasmic binding protein [KO:K02020]
Plut_1709  Molybdate ABC transporter, permease protein [KO:K02018]
Plut_1542  putative transmembrane protein [KO:K02018]
Plut_1710  Molybdate ABC transporter, ATP-binding protein [KO:K02017] [EC:]
Plut_1712  ATPase [KO:K02017] [EC:]
Plut_0440  VpsC protein [KO:K02067]
Plut_0442  putative ABC transport system permease protein [KO:K02066]
Plut_0441  ATPase [KO:K02065]
Plut_1246  phosphate ABC transporter substrate-binding protein, PhoT family [KO:K02040]
Plut_1244  phosphate ABC transporter membrane protein 1, PhoT family [KO:K02037]
Plut_1243  phosphate ABC transporter membrane protein 2, PhoT family [KO:K02038]
Plut_1242  phosphate ABC transporter ATP-binding protein, PhoT family [KO:K02036] [EC:]
Plut_1148  ABC transporter, periplasmic substrate-binding protein [KO:K02016]
Plut_1136  FecCD transport family protein [KO:K02015]
Plut_0729  ATPase [KO:K02013] [EC:]
Plut_0139  adhesion protein, putative [KO:K09815]
Plut_0141  ABC 3 transport family protein [KO:K09816]
Plut_0140  ATPase [KO:K09817] [EC:3.6.3.-]
Plut_1451  putative cobalt transport protein [KO:K02009]
Plut_1450  Cobalamin biosynthesis protein CbiM [KO:K02007]
Plut_1452  cobalt transport protein [KO:K02008]
Plut_1453  ATPase [KO:K02006]
Plut_1599  lipoprotein releasing system [KO:K09808]
Plut_1763  putative ABC transporter, integral membrane protein [KO:K09808]
Plut_1053  probable ABC transporter permease protein [KO:K09808]
Plut_1052  conserved hypothetical protein [KO:K09808]
Plut_1480  ATPase [KO:K09810] [EC:3.6.3.-]
Plut_1701  ATPase [KO:K09810] [EC:3.6.3.-]
Plut_0723  conserved hypothetical protein [KO:K07091]
Plut_0389  conserved hypothetical protein [KO:K11720]
Plut_0288  ATPase [KO:K06861] [EC:3.6.3.-]
Plut_0427  cell division protein FtsX [KO:K09811]
Plut_0578  cell division ATP-binding protein FtsE [KO:K09812]
Plut_1803  ATPase [KO:K11085] [EC:3.6.3.-]
Plut_1502  ATPase [KO:K18889]
Plut_1761  ATPase [KO:K18890]
Plut_0381  ATPase [KO:K12541]
Plut_0679  Type I secretion system ATPase, PrtD [KO:K12536]
Plut_0680  Type I secretion system ATPase, PrtD [KO:K12536]
Plut_0472  ATPase [KO:K16012]
Plut_0473  ATPase [KO:K16013]
Plut_0496  ATPase [KO:K05685] [EC:3.6.3.-]
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00045  Amino acid
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00315  Spermidine
C00320  Thiosulfate
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00719  Betaine
C00753  Tungsten
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  D-Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06228  Ferrichrome
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06704  Iron chelate
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C16059  Defensin beta-1
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
D02224  Protamine sulfate (JP17/USP/INN)
G00457  Maltotetraose
Tomii K, Kanehisa M.
A comparative analysis of ABC transporters in complete microbial genomes.
Genome Res 8:1048-59 (1998)
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
J Bacteriol 190:4460-9 (2008)
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Proc Natl Acad Sci U S A 105:5537-42 (2008)
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Proc Natl Acad Sci U S A 96:13571-6 (1999)
Quintero MJ, Montesinos ML, Herrero A, Flores E
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Genome Res 11:2034-40 (2001)
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Mol Microbiol 57:1582-92 (2005)
Valladares A, Montesinos ML, Herrero A, Flores E.
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Mol Microbiol 43:703-15 (2002)
Richard-Fogal CL, Frawley ER, Kranz RG
Topology and function of CcmD in cytochrome c maturation.
J Bacteriol 190:3489-93 (2008)
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
J Bacteriol 187:5861-7 (2005)
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
J Bacteriol 189:8361-5 (2007)
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Mol Microbiol 63:895-910 (2007)
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
J Bacteriol 190:7693-8 (2008)
KO pathway

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