KEGG   PATHWAY: pog02010Help
Entry
pog02010                    Pathway                                

Name
ABC transporters - Pyrobaculum oguniense
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
pog02010  ABC transporters
pog02010

Ortholog table
Module
pog_M00191  Thiamine transport system [PATH:pog02010]
pog_M00201  alpha-Glucoside transport system [PATH:pog02010]
pog_M00203  Glucose/arabinose transport system [PATH:pog02010]
pog_M00222  Phosphate transport system [PATH:pog02010]
pog_M00237  Branched-chain amino acid transport system [PATH:pog02010]
pog_M00239  Peptides/nickel transport system [PATH:pog02010]
pog_M00240  Iron complex transport system [PATH:pog02010]
pog_M00299  Spermidine/putrescine transport system [PATH:pog02010]
pog_M00423  Molybdate/tungstate transport system [PATH:pog02010]
pog_M00491  arabinogalactan oligomer/maltooligosaccharide transport system [PATH:pog02010]
Other DBs
BSID: 568688
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Pyrobaculum oguniense [GN:pog]
Gene
Pogu_1711  hypothetical protein [KO:K05772]
Pogu_0703  ABC-type molybdate transport system, periplasmic component [KO:K15495]
Pogu_0704  ABC-type sulfate transport system, permease component [KO:K15496]
Pogu_0705  ABC-type sugar transport systems, ATPase component [KO:K15497] [EC:3.6.3.55 3.6.3.-]
Pogu_2746  ABC transporter periplasmic binding protein, thiB subfamily [KO:K02064]
Pogu_2745  ABC-type Fe3+ transport system, permease component [KO:K02063]
Pogu_2744  ABC-type sugar transport systems, ATPase component [KO:K02062]
Pogu_2335  Spermidine/putrescine-binding periplasmic protein [KO:K11069]
Pogu_1367  ABC-type spermidine/putrescine transport system, permease component II [KO:K11070]
Pogu_1368  ABC-type spermidine/putrescine transport system, permease component I [KO:K11071]
Pogu_1369  ABC-type spermidine/putrescine transport systems, ATPase component [KO:K11072] [EC:3.6.3.31]
Pogu_1953  ABC-type sugar transport systems, ATPase component [KO:K10112]
Pogu_0265  Maltose-binding periplasmic protein/domains [KO:K15770]
Pogu_0266  ABC-type sugar transport systems, permease component [KO:K15771]
Pogu_0267  ABC-type maltose transport systems, permease component [KO:K15772]
Pogu_2523  ABC-type sugar transport system, periplasmic component [KO:K10196]
Pogu_2524  ABC-type sugar transport systems, permease component [KO:K10197]
Pogu_2525  ABC-type sugar transport system, permease component [KO:K10198]
Pogu_1921  phosphate ABC transporter, phosphate-binding protein [KO:K02040]
Pogu_1920  phosphate ABC transporter, permease protein PstC [KO:K02037]
Pogu_1919  ABC-type phosphate transport system, permease component [KO:K02038]
Pogu_1918  ABC-type phosphate transport system, ATPase component [KO:K02036] [EC:3.6.3.27]
Pogu_2215  phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein [KO:K02044]
Pogu_2217  ABC-type phosphate/phosphonate transport system, permease component [KO:K02042]
Pogu_1917  ABC-type branched-chain amino acid transport systems, periplasmic component [KO:K01999]
Pogu_1361  ABC-type branched-chain amino acid transport systems, periplasmic component [KO:K01999]
Pogu_0369  ABC-type branched-chain amino acid transport systems, periplasmic component [KO:K01999]
Pogu_0434  ABC-type branched-chain amino acid transport systems, periplasmic component [KO:K01999]
Pogu_2662  ABC-type branched-chain amino acid transport systems, periplasmic component [KO:K01999]
Pogu_1916  Branched-chain amino acid ABC-type transport system, permease component [KO:K01997]
Pogu_0370  Branched-chain amino acid ABC-type transport system, permease component [KO:K01997]
Pogu_2661  Branched-chain amino acid ABC-type transport system, permease component [KO:K01997]
Pogu_1915  ABC-type branched-chain amino acid transport system, permease component [KO:K01998]
Pogu_0371  ABC-type branched-chain amino acid transport system, permease component [KO:K01998]
Pogu_2660  ABC-type branched-chain amino acid transport system, permease component [KO:K01998]
Pogu_1363  ABC-type branched-chain amino acid transport system, permease component [KO:K01998]
Pogu_1914  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995]
Pogu_1364  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995]
Pogu_1815  ABC-type spermidine/putrescine transport systems, ATPase component [KO:K01995]
Pogu_0368  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995]
Pogu_2666  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995]
Pogu_1092  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995]
Pogu_1913  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996]
Pogu_2665  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996]
Pogu_0433  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996]
Pogu_1365  ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996]
Pogu_1362  Branched-chain amino acid ABC-type transport system, permease component [KO:K11956]
Pogu_0931  ABC-type Fe3+-hydroxamate transport system, periplasmic component [KO:K02016]
Pogu_2751  ABC-type Fe3+-hydroxamate transport system, periplasmic component [KO:K02016]
Pogu_0930  ABC-type Fe3+-siderophore transport system, permease component [KO:K02015]
Pogu_2750  ABC-type Fe3+-siderophore transport system, permease component [KO:K02015]
Pogu_0929  ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase component [KO:K02013] [EC:3.6.3.34]
Pogu_0923  hypothetical protein [KO:K02009]
Pogu_0924  ABC-type Co2+ transport system, permease component [KO:K02007]
Pogu_1062  ABC-type cobalt transport system, ATPase component [KO:K16786 K16787] [EC:3.6.3.- 3.6.3.-]
Pogu_0921  ABC-type cobalt transport system, ATPase component [KO:K16787] [EC:3.6.3.-]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00045  Amino acid
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00315  Spermidine
C00320  Thiosulfate
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00719  Betaine
C00753  Tungsten
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  D-Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06228  Ferrichrome
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06704  Iron chelate
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C16059  Defensin beta-1
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
D02224  Protamine sulfate (JP17/USP/INN)
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   

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