| Entry |
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| Name |
Regulation of autophagy - Pichia pastoris
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| Class |
Cellular Processes; Transport and catabolism
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| Pathway map |
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| Other DBs |
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| Organism |
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| Gene |
| Protein serine/threonine kinase required for vesicle formation in autophagy; K08269 unc51-like kinase [EC: 2.7.11.1] [KO: K08269] [EC: 2.7.11.1] | | Scaffold protein responsible for pre-autophagosomal structure organization; K08329 autophagy-related protein 17 [KO: K08329] | | Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; K08330 autophagy-related protein 11 [KO: K08330] | | Regulatory subunit of the Atg1p signaling complex; K08331 autophagy-related protein 13 [KO: K08331] | | Phosphorylated vacuolar membrane protein that interacts with Atg13p; K08332 vacuolar protein 8 [KO: K08332] | | Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; K08333 phosphoinositide-3-kinase, regulatory subunit 4, p150 [EC: 2.7.11.1] [KO: K08333] [EC: 2.7.11.1] | | Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; K08334 beclin 1 [KO: K08334] | | Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; K00914 phosphatidylinositol 3-kinase [EC: 2.7.1.137] [KO: K00914] [EC: 2.7.1.137] | | Conserved ubiquitin-like modifier; K08336 autophagy-related protein 12 [KO: K08336] | | Autophagy-related protein; K08337 autophagy-related protein 7 [KO: K08337] | | Conserved protein involved in autophagy and the Cvt pathway; K08339 autophagy-related protein 5 [KO: K08339] | | Conserved protein that is a component of autophagosomes and Cvt vesicles; K08341 GABA(A) receptor-associated protein (autophagy-related protein 8) [KO: K08341] | | Conserved cysteine protease required for autophagy; K08342 autophagy-related protein 4 [EC:3.4.22.-] [KO: K08342] [EC:3.4.22.-] | | E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; K08343 autophagy-related protein 3 [KO: K08343] |
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| Compound |
| Phosphatidylethanolamine | | 3-Methyladenine | | 1-Phosphatidyl-D-myo-inositol | | 1-Phosphatidyl-1D-myo-inositol 3-phosphate | | Wortmannin |
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| Reference |
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| Authors |
Meijer AJ, Codogno P. |
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| Title |
Regulation and role of autophagy in mammalian cells. |
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| Journal |
Int J Biochem Cell Biol 36:2445-62 (2004) |
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| Reference |
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| Authors |
Deretic V. |
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| Title |
Autophagy in innate and adaptive immunity. |
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| Journal |
Trends Immunol 26:523-8 (2005) |
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| Reference |
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| Authors |
Thompson AR, Vierstra RD. |
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| Title |
Autophagic recycling: lessons from yeast help define the process in plants. |
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| Journal |
Curr Opin Plant Biol 8:165-73 (2005) |
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| Reference |
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| Authors |
Levine B, Yuan J. |
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| Title |
Autophagy in cell death: an innocent convict? |
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| Journal |
J Clin Invest 115:2679-88 (2005) |
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| Reference |
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| Authors |
Tanida I, Ueno T, Kominami E. |
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| Title |
LC3 conjugation system in mammalian autophagy. |
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| Journal |
Int J Biochem Cell Biol 36:2503-18 (2004) |
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| Reference |
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| Authors |
Lum JJ, DeBerardinis RJ, Thompson CB. |
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| Title |
Autophagy in metazoans: cell survival in the land of plenty. |
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| Journal |
Nat Rev Mol Cell Biol 6:439-48 (2005) |
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| Reference |
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| Authors |
Reggiori F, Klionsky DJ. |
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| Title |
Autophagosomes: biogenesis from scratch? |
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| Journal |
Curr Opin Cell Biol 17:415-22 (2005) |
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| Reference |
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| Authors |
Klionsky DJ, Emr SD. |
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| Title |
Autophagy as a regulated pathway of cellular degradation. |
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| Journal |
Science 290:1717-21 (2000) |
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| Reference |
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| Authors |
Bechet D, Tassa A, Taillandier D, Combaret L, Attaix D. |
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| Title |
Lysosomal proteolysis in skeletal muscle. |
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| Journal |
Int J Biochem Cell Biol 37:2098-114 (2005) |
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| KO pathway |
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