KEGG   PATHWAY: pps04530
Entry
pps04530                    Pathway                                
Name
Tight junction - Pan paniscus (bonobo)
Description
Tight junctions (TJs) are essential for establishing a selectively permeable barrier to diffusion through the paracellular space between neighboring cells. TJs are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of many different proteins that form large complexes. These are proposed to be involved in junction assembly, barrier regulation, cell polarity, gene transcription, and other pathways.
Class
Cellular Processes; Cellular community - eukaryotes
Pathway map
pps04530  Tight junction
pps04530

Other DBs
GO: 0005923
Organism
Pan paniscus (bonobo) [GN:pps]
Gene
100992540  CRB3; protein crumbs homolog 3 [KO:K06090]
100993019  CLDN9; claudin-9 [KO:K06087]
100993728  CLDN6; claudin-6 [KO:K06087]
100983225  CLDN25; putative claudin-25 [KO:K06087]
100972056  CLDN23; claudin-23 [KO:K06087]
100968048  CLDN15; claudin-15 [KO:K06087]
100973023  CLDN34; claudin-34 [KO:K06087]
100996190  CLDN19; claudin-19 isoform X1 [KO:K06087]
100987641  CLDN17; claudin-17 [KO:K06087]
100988328  CLDN8; claudin-8 [KO:K06087]
100975200  CLDN3; claudin-3 [KO:K06087]
100975921  CLDN18; claudin-18 [KO:K06087]
100969089  putative claudin-24 [KO:K06087]
100989749  CLDN1; claudin-1 [KO:K06087]
100990092  CLDN16; claudin-16 isoform X2 [KO:K06087]
100980857  CLDN11; claudin-11 isoform X1 [KO:K06087]
100978259  CLDN10; claudin-10 isoform X2 [KO:K06087]
100973750  CLDN4; claudin-4 [KO:K06087]
100989187  CLDN7; claudin-7 [KO:K06087]
103786942  CLDN22; claudin-22 [KO:K06087]
100979803  CLDN5; claudin-5 [KO:K06087]
100980342  CLDN14; claudin-14 [KO:K06087]
100976803  CLDN2; claudin-2 [KO:K06087]
100975465  CLDN20; claudin-20 [KO:K06087]
100989654  CLDN12; claudin-12 [KO:K06087]
103783517  claudin-12 [KO:K06087]
100988387  OCLN; occludin [KO:K06088]
100985293  F11R; junctional adhesion molecule A [KO:K06089]
100968362  JAM2; junctional adhesion molecule B [KO:K06735]
100982769  JAM3; junctional adhesion molecule C [KO:K06785]
100981011  BVES; blood vessel epicardial substance [KO:K21108]
100993131  cell division control protein 42 homolog [KO:K04393]
100990246  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
100982056  PARD6A; partitioning defective 6 homolog alpha isoform X3 [KO:K06093]
100976443  PARD6B; partitioning defective 6 homolog beta [KO:K06093]
100969313  PARD6G; partitioning defective 6 homolog gamma [KO:K06093]
100970838  MPP5; MAGUK p55 subfamily member 5 isoform X1 [KO:K06091]
100982114  MPP4; MAGUK p55 subfamily member 4 [KO:K21109]
100984330  TJP3; tight junction protein ZO-3 isoform X7 [KO:K06097]
100984381  PATJ; inaD-like protein isoform X1 [KO:K06092]
100989616  MPDZ; multiple PDZ domain protein isoform X1 [KO:K06095]
100987713  PRKCZ; protein kinase C zeta type isoform X1 [KO:K18952] [EC:2.7.11.13]
100979245  PRKCI; protein kinase C iota type [KO:K06069] [EC:2.7.11.13]
100993839  AMOT; angiomotin isoform X1 [KO:K16819]
100993631  AMOTL2; angiomotin-like protein 2 isoform X1 [KO:K06104]
100981618  AMOTL1; angiomotin-like protein 1 isoform X1 [KO:K06104]
100988440  ARHGAP17; rho GTPase-activating protein 17 isoform X1 [KO:K20638]
100989777  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
100976112  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
100994915  NF2; merlin isoform X1 [KO:K16684]
100991928  LLGL2; LLGL scribble cell polarity complex component 2 isoform X6 [KO:K06094]
100973006  LLGL1; lethal(2) giant larvae protein homolog 1 isoform X1 [KO:K06094]
100987596  DLG1; disks large homolog 1 isoform X4 [KO:K12076]
100970225  SCRIB; protein scribble homolog isoform X1 [KO:K16175]
100987323  serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
100981626  PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
100976101  PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
100995920  PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform [KO:K03456]
100991308  PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X4 [KO:K03456]
100983884  PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X2 [KO:K04354]
100991998  PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 [KO:K04354]
100990236  PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X5 [KO:K04354]
100968814  PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X2 [KO:K04354]
100990710  PARD3; partitioning defective 3 homolog isoform X1 [KO:K04237]
100967869  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
100986510  TJP1; tight junction protein ZO-1 isoform X1 [KO:K05701]
100982308  TJAP1; tight junction-associated protein 1 isoform X2 [KO:K06105]
100987358  DLG3; disks large homolog 3 isoform X1 [KO:K21098]
100969945  NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X2 [KO:K10591] [EC:2.3.2.26]
100974611  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1 [KO:K13305] [EC:2.3.2.26]
100989132  CGN; cingulin [KO:K06102]
100975161  CGNL1; cingulin-like protein 1 isoform X2 [KO:K21110]
100985016  ARHGEF2; rho guanine nucleotide exchange factor 2 isoform X7 [KO:K12791]
100995642  RHOA; transforming protein RhoA [KO:K04513]
100972735  GATA4; transcription factor GATA-4 [KO:K09183]
100989099  MARVELD3; MARVEL domain-containing protein 3 isoform X1 [KO:K21099]
100994796  MAP3K1; mitogen-activated protein kinase kinase kinase 1 isoform X1 [KO:K04416] [EC:2.7.11.25]
100984173  MAPK10; mitogen-activated protein kinase 10 isoform X3 [KO:K04440] [EC:2.7.11.24]
100982480  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
100990080  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
100980908  JUN; transcription factor AP-1 [KO:K04448]
100985794  CD1E; T-cell surface glycoprotein CD1e, membrane-associated isoform X1 [KO:K06448]
100986789  CD1B; T-cell surface glycoprotein CD1b [KO:K06448]
100987121  CD1A; T-cell surface glycoprotein CD1a isoform X1 [KO:K06448]
100987470  CD1C; T-cell surface glycoprotein CD1c isoform X2 [KO:K06448]
100988149  CD1D; antigen-presenting glycoprotein CD1d isoform X1 [KO:K06448]
100989405  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
100976294  CDK4; cyclin-dependent kinase 4 isoform X1 [KO:K02089] [EC:2.7.11.22]
100974418  YBX3; Y-box-binding protein 3 isoform X2 [KO:K06099]
100983890  SYMPK; symplekin [KO:K06100]
100987805  PCNA; proliferating cell nuclear antigen [KO:K04802]
100995605  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
100977227  ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
100985479  RUNX1; runt-related transcription factor 1 isoform X1 [KO:K08367]
100984646  HSPA4; heat shock 70 kDa protein 4 [KO:K09489]
100976426  SLC9A3R1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [KO:K13365]
100983688  EZR; ezrin isoform X2 [KO:K08007]
100989730  RDX; radixin isoform X1 [KO:K05762]
100980973  MSN; moesin [KO:K05763]
100974922  PRKCE; protein kinase C epsilon type isoform X1 [KO:K18050] [EC:2.7.11.13]
100970542  ACTG1; actin, cytoplasmic 2 [KO:K05692]
100990579  actin, cytoplasmic 1 [KO:K05692]
103784606  actin, alpha skeletal muscle-like [KO:K05692]
100987964  LOW QUALITY PROTEIN: actin-like [KO:K05692]
100975108  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X3 [KO:K04851]
100991014  MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X2 [KO:K04426] [EC:2.7.11.25]
100989537  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
100986423  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
100977185  HCLS1; hematopoietic lineage cell-specific protein [KO:K06106]
100975850  CTTN; src substrate cortactin isoform X1 [KO:K06106]
100984419  ACTR2; actin-related protein 2 isoform X2 [KO:K17260]
100991091  ACTR3; actin-related protein 3 [KO:K18584]
106635013  ACTR3C; actin-related protein 3C isoform X1 [KO:K18584]
117981155  ACTR3B; actin-related protein 3B isoform X1 [KO:K18584]
100979355  ARPC1A; actin-related protein 2/3 complex subunit 1A [KO:K05757]
100975648  ARPC1B; actin-related protein 2/3 complex subunit 1B [KO:K05757]
100981873  ARPC2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
100973986  ARPC3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
100984731  actin-related protein 2/3 complex subunit 3-like [KO:K05756]
100968230  ARPC4; actin-related protein 2/3 complex subunit 4 isoform X2 [KO:K05755]
100991419  ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
100967312  ARPC5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
100968586  WHAMM; WASP homolog-associated protein with actin, membranes and microtubules isoform X2 [KO:K20479]
100977168  WAS; wiskott-Aldrich syndrome protein [KO:K05747]
100986884  VASP; vasodilator-stimulated phosphoprotein isoform X1 [KO:K06274]
100982589  PRKACG; cAMP-dependent protein kinase catalytic subunit gamma [KO:K04345] [EC:2.7.11.11]
100970917  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X5 [KO:K04345] [EC:2.7.11.11]
100968237  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
100977458  RAB13; ras-related protein Rab-13 isoform X2 [KO:K06109]
103787156  ras-related protein Rab-13-like [KO:K06109]
100991562  rho guanine nucleotide exchange factor 18 isoform X1 [KO:K21066]
100976232  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
100969111  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
100973169  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
100985845  EPB41L4B; band 4.1-like protein 4B isoform X1 [KO:K21111]
100989684  STK11; serine/threonine-protein kinase STK11 isoform X3 [KO:K07298] [EC:2.7.11.1]
100975618  PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2 [KO:K07198] [EC:2.7.11.31]
100991417  PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2 [KO:K07198] [EC:2.7.11.31]
100972311  PRKAB2; 5'-AMP-activated protein kinase subunit beta-2 [KO:K07199]
100975205  PRKAB1; 5'-AMP-activated protein kinase subunit beta-1 [KO:K07199]
100996156  PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1 isoform X2 [KO:K07200]
100987544  PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 isoform X12 [KO:K07200]
100989947  PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3 [KO:K07200]
100979597  MYH10; myosin-10 isoform X1 [KO:K10352]
100993958  MYH11; myosin-11 isoform X1 [KO:K10352]
100984241  MYH9; myosin-9 isoform X1 [KO:K10352]
100987315  MYH14; myosin-14 isoform X1 [KO:K10352]
100977624  MYL6B; myosin light chain 6B isoform X2 [KO:K12751]
100978420  MYL6; myosin light polypeptide 6 isoform X1 [KO:K12751]
100989544  myosin light polypeptide 6-like [KO:K12751]
100995742  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
100977910  myosin regulatory light chain 12B [KO:K12757]
100978696  myosin regulatory light chain 12A isoform X2 [KO:K12757]
100972981  myosin regulatory light chain 12B [KO:K12757]
117980785  myosin regulatory light chain 12B-like [KO:K12757]
100992001  IGSF5; LOW QUALITY PROTEIN: immunoglobulin superfamily member 5 [KO:K06786]
100974840  MAGI1; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X13 [KO:K05631]
100970287  synaptopodin isoform X1 [KO:K21112]
100979183  ACTN1; alpha-actinin-1 isoform X2 [KO:K05699]
100981951  ACTN4; alpha-actinin-4 isoform X3 [KO:K05699]
100970323  MICALL2; MICAL-like protein 2 isoform X5 [KO:K21068]
100993687  RAB8A; ras-related protein Rab-8A [KO:K07901]
100969254  RAB8B; ras-related protein Rab-8B isoform X1 [KO:K07902]
100968786  RAPGEF6; rap guanine nucleotide exchange factor 6 isoform X2 [KO:K08020]
100980934  RAP1A; ras-related protein Rap-1A [KO:K04353]
100992059  ITGB1; integrin beta-1 [KO:K05719]
100994843  AFDN; afadin isoform X10 [KO:K05702]
100980690  TJP2; tight junction protein ZO-2 isoform X3 [KO:K06098]
100972977  RAPGEF2; rap guanine nucleotide exchange factor 2 isoform X1 [KO:K08018]
100977784  RAP2C; ras-related protein Rap-2c [KO:K07839]
100988729  MARVELD2; MARVEL domain-containing protein 2 isoform X1 [KO:K17291]
100995882  tubulin alpha-4A chain isoform X1 [KO:K07374]
100986068  TUBA8; tubulin alpha-8 chain isoform X1 [KO:K07374]
100989319  TUBAL3; tubulin alpha chain-like 3 isoform X1 [KO:K07374]
103782837  tubulin alpha-1B chain [KO:K07374]
100993591  tubulin alpha-3 chain [KO:K07374]
100970502  TUBA1C; tubulin alpha-1C chain isoform X1 [KO:K07374]
100993058  tubulin alpha-1A chain isoform X1 [KO:K07374]
100973193  tubulin alpha-3 chain [KO:K07374]
100975223  tubulin alpha-3 chain-like [KO:K07374]
Compound
C00076  Calcium cation
Reference
PMID:27353478
  Authors
Zihni C, Mills C, Matter K, Balda MS
  Title
Tight junctions: from simple barriers to multifunctional molecular gates.
  Journal
Nat Rev Mol Cell Biol 17:564-80 (2016)
DOI:10.1038/nrm.2016.80
Reference
PMID:22169974
  Authors
Martin-Belmonte F, Perez-Moreno M
  Title
Epithelial cell polarity, stem cells and cancer.
  Journal
Nat Rev Cancer 12:23-38 (2011)
DOI:10.1038/nrc3169
Reference
PMID:17525755
  Authors
Weber C, Fraemohs L, Dejana E
  Title
The role of junctional adhesion molecules in vascular inflammation.
  Journal
Nat Rev Immunol 7:467-77 (2007)
DOI:10.1038/nri2096
Reference
PMID:15820555
  Authors
Miyoshi J, Takai Y
  Title
Molecular perspective on tight-junction assembly and epithelial polarity.
  Journal
Adv Drug Deliv Rev 57:815-55 (2005)
DOI:10.1016/j.addr.2005.01.008
Reference
PMID:16650994
  Authors
Mertens AE, Pegtel DM, Collard JG
  Title
Tiam1 takes PARt in cell polarity.
  Journal
Trends Cell Biol 16:308-16 (2006)
DOI:10.1016/j.tcb.2006.04.001
Reference
PMID:16771626
  Authors
Shin K, Fogg VC, Margolis B
  Title
Tight junctions and cell polarity.
  Journal
Annu Rev Cell Dev Biol 22:207-35 (2006)
DOI:10.1146/annurev.cellbio.22.010305.104219
Reference
PMID:17182900
  Authors
Kooistra MR, Dube N, Bos JL
  Title
Rap1: a key regulator in cell-cell junction formation.
  Journal
J Cell Sci 120:17-22 (2007)
DOI:10.1242/jcs.03306
Reference
PMID:17950242
  Authors
Gonzalez-Mariscal L, Tapia R, Chamorro D
  Title
Crosstalk of tight junction components with signaling pathways.
  Journal
Biochim Biophys Acta 1778:729-56 (2008)
DOI:10.1016/j.bbamem.2007.08.018
Reference
PMID:18005931
  Authors
Assemat E, Bazellieres E, Pallesi-Pocachard E, Le Bivic A, Massey-Harroche D
  Title
Polarity complex proteins.
  Journal
Biochim Biophys Acta 1778:614-30 (2008)
DOI:10.1016/j.bbamem.2007.08.029
Reference
PMID:18946474
  Authors
Iden S, Collard JG
  Title
Crosstalk between small GTPases and polarity proteins in cell polarization.
  Journal
Nat Rev Mol Cell Biol 9:846-59 (2008)
DOI:10.1038/nrm2521
Reference
PMID:20094051
  Authors
Rosse C, Linch M, Kermorgant S, Cameron AJ, Boeckeler K, Parker PJ
  Title
PKC and the control of localized signal dynamics.
  Journal
Nat Rev Mol Cell Biol 11:103-12 (2010)
DOI:10.1038/nrm2847
Reference
PMID:20134025
  Authors
Terry S, Nie M, Matter K, Balda MS
  Title
Rho signaling and tight junction functions.
  Journal
Physiology (Bethesda) 25:16-26 (2010)
DOI:10.1152/physiol.00034.2009
Reference
PMID:21283798
  Authors
Russ PK, Pino CJ, Williams CS, Bader DM, Haselton FR, Chang MS
  Title
Bves modulates tight junction associated signaling.
  Journal
PLoS One 6:e14563 (2011)
DOI:10.1371/journal.pone.0014563
Reference
PMID:21781017
  Authors
Citi S, Spadaro D, Schneider Y, Stutz J, Pulimeno P
  Title
Regulation of small GTPases at epithelial cell-cell junctions.
  Journal
Mol Membr Biol 28:427-44 (2011)
DOI:10.3109/09687688.2011.603101
Reference
PMID:22896795
  Authors
Lickert H, Van Campenhout CA
  Title
Evolution of the Discs large gene family provides new insights into the establishment of apical epithelial polarity and the etiology of mental retardation.
  Journal
Commun Integr Biol 5:287-90 (2012)
DOI:10.4161/cib.19792
Reference
PMID:22928510
  Authors
Spadaro D, Tapia R, Pulimeno P, Citi S
  Title
The control of gene expression and cell proliferation by the epithelial apical junctional complex.
  Journal
Essays Biochem 53:83-93 (2012)
DOI:10.1042/bse0530083
Reference
PMID:24548561
  Authors
Moleirinho S, Guerrant W, Kissil JL
  Title
The Angiomotins--from discovery to function.
  Journal
FEBS Lett 588:2693-703 (2014)
DOI:10.1016/j.febslet.2014.02.006
Reference
PMID:24651541
  Authors
Rodriguez-Boulan E, Macara IG
  Title
Organization and execution of the epithelial polarity programme.
  Journal
Nat Rev Mol Cell Biol 15:225-42 (2014)
DOI:10.1038/nrm3775
Reference
PMID:25152334
  Authors
Gonzalez-Mariscal L, Dominguez-Calderon A, Raya-Sandino A, Ortega-Olvera JM, Vargas-Sierra O, Martinez-Revollar G
  Title
Tight junctions and the regulation of gene expression.
  Journal
Semin Cell Dev Biol 36:213-23 (2014)
DOI:10.1016/j.semcdb.2014.08.009
Reference
PMID:25469537
  Authors
Mack NA, Georgiou M
  Title
The interdependence of the Rho GTPases and apicobasal cell polarity.
  Journal
Small GTPases 5:10 (2014)
DOI:10.4161/21541248.2014.973768
Reference
PMID:25483301
  Authors
Citi S, Guerrera D, Spadaro D, Shah J
  Title
Epithelial junctions and Rho family GTPases: the zonular signalosome.
  Journal
Small GTPases 5:1-15 (2014)
DOI:10.4161/21541248.2014.973760
Reference
PMID:25757376
  Authors
Zihni C, Terry SJ
  Title
RhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancer.
  Journal
Int J Biochem Cell Biol 64:120-5 (2015)
DOI:10.1016/j.biocel.2015.02.020
Reference
PMID:22892070
  Authors
Nakano A, Takashima S
  Title
LKB1 and AMP-activated protein kinase: regulators of cell polarity.
  Journal
Genes Cells 17:737-47 (2012)
DOI:10.1111/j.1365-2443.2012.01629.x
Reference
PMID:12042308
  Authors
Patrie KM, Drescher AJ, Welihinda A, Mundel P, Margolis B
  Title
Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1.
  Journal
J Biol Chem 277:30183-90 (2002)
DOI:10.1074/jbc.M203072200
Reference
PMID:18094055
  Authors
Yamamura R, Nishimura N, Nakatsuji H, Arase S, Sasaki T
  Title
The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.
  Journal
Mol Biol Cell 19:971-83 (2008)
DOI:10.1091/mbc.E07-06-0551
Reference
PMID:23885123
  Authors
Monteiro AC, Sumagin R, Rankin CR, Leoni G, Mina MJ, Reiter DM, Stehle T, Dermody TS, Schaefer SA, Hall RA, Nusrat A, Parkos CA
  Title
JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.
  Journal
Mol Biol Cell 24:2849-60 (2013)
DOI:10.1091/mbc.E13-06-0298
Related
pathway
pps04520  Adherens junction
pps04810  Regulation of actin cytoskeleton
KO pathway
ko04530   

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Genome (1)   
   KEGG GENOME (1)   
Gene (180)   
   KEGG GENES (180)   
All databases (181)   

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