KEGG   PATHWAY: ptr04612Help
Entry
ptr04612                    Pathway                                

Name
Antigen processing and presentation - Pan troglodytes (chimpanzee)
Class
Organismal Systems; Immune system
BRITE hierarchy
Pathway map
Antigen processing and presentation
ptr04612

All organismsOrtholog table
Other DBs
Organism
Pan troglodytes (chimpanzee) [GN:ptr]
Gene
449517  
IFNG; interferon, gamma [KO:K04687]
494186  
TNF; tumor necrosis factor [KO:K03156]
452809  
PSME1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) [KO:K06696]
744802  
PSME2; proteasome (prosome, macropain) activator subunit 2 (PA28 beta) [KO:K06697]
740582  
PSME3; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma [KO:K06698]
450139  
HSPA2; heat shock 70kDa protein 2 [KO:K03283]
471967  
HSPA1L; heat shock 70kDa protein 1-like [KO:K03283]
451629  
HSPA8; heat shock 70kDa protein 8 [KO:K03283]
HSPA1A; heat shock 70kDa protein 1A [KO:K03283]
462060  
HSPA4; heat shock 70kDa protein 4 [KO:K09489]
743883  
HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1 [KO:K04079]
737497  
HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1 [KO:K04079]
746963  
putative heat shock protein HSP 90-beta 4-like; K04079 molecular chaperone HtpG [KO:K04079]
461365  
putative heat shock protein HSP 90-beta-3-like; K04079 molecular chaperone HtpG [KO:K04079]
450202  
PATR-B; major histocompatibility complex, class I, B [KO:K06751]
471962  
PATR-C; major histocompatibility complex, class I, C [KO:K06751]
462540  
PATR-E; major histocompatibility complex, class I, E [KO:K06751]
494187  
PATR-G; MHC class Ib [KO:K06751]
450151  
PATR-A; major histocompatibility complex, class I, A [KO:K06751]
749652  
patr class I histocompatibility antigen; K06751 major histocompatibility complex, class I [KO:K06751]
463178  
PATR-AL; major histocompatibility complex, class I, AL [KO:K06751]
PATR-F; major histocompatibility complex, class I, F [KO:K06751]
462330  
CANX; calnexin [KO:K08054]
450170  
B2M; beta-2-microglobulin [KO:K08055]
742723  
PDIA3; protein disulfide isomerase family A, member 3 [KO:K08056] [EC:5.3.4.1]
455756  
CALR; calreticulin [KO:K08057]
746814  
TAPBP; TAP binding protein (tapasin) [KO:K08058]
471978  
TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) [KO:K05653]
746399  
TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) [KO:K05654]
735755  
CD8A; CD8a molecule [KO:K06458]
470426  
CD8B; CD8b molecule [KO:K06459]
743494  
T-cell receptor alpha chain V region RL-5-like; K10784 T cell receptor alpha chain V region [KO:K10784]
BV7-9; uncharacterized LOC100615597 [KO:K10785]
BV10-1; uncharacterized LOC100613861 [KO:K10785]
T-cell receptor beta chain T17T-22-like; K10785 T-cell receptor beta chain V region [KO:K10785]
T-cell receptor beta chain T17T-22-like; K10785 T-cell receptor beta chain V region [KO:K10785]
742771  
T-cell receptor beta chain T17T-22-like; K10785 T-cell receptor beta chain V region [KO:K10785]
456291  
KIR3DL1; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 [KO:K07980]
KIR3DL3; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 [KO:K07980]
KIR3DL5; killer cell immunoglobulin-like receptor [KO:K07980]
KIR3DL4; killer cell immunoglobulin-like receptor [KO:K07980]
450205  
KIR2DL4; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 [KO:K07981]
KIR2DL1; killer cell immunoglobulin-like receptor [KO:K07981]
748992  
KIR2DL5A; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A [KO:K07981]
449624  
KLRC3; killer cell lectin-like receptor subfamily C, member 3 [KO:K06541]
450131  
KLRC1; killer cell lectin-like receptor subfamily C, member 1 [KO:K06541]
450145  
KLRC4; killer cell lectin-like receptor subfamily C, member 4 [KO:K06541]
450132  
KLRC2; killer cell lectin-like receptor subfamily C, member 2 [KO:K06541]
NKG2-C type II integral membrane protein-like; K06541 killer cell lectin-like receptor subfamily C [KO:K06541]
450156  
KLRD1; killer cell lectin-like receptor subfamily D, member 1 [KO:K06516]
748630  
IFI30; interferon, gamma-inducible protein 30 [KO:K08059]
453118  
LGMN; legumain [KO:K01369] [EC:3.4.22.34]
463993  
CTSB; cathepsin B [KO:K01363] [EC:3.4.22.1]
449592  
PATR-DMB; major histocompatibility complex, class II, DM beta [KO:K06752]
471974  
PATR-DQA1; major histocompatibility complex, class II, DQ alpha 1 [KO:K06752]
471976  
PATR-DQA2; major histocompatibility complex, class II, DQ alpha 2 [KO:K06752]
471977  
PATR-DOB; major histocompatibility complex, class II, DO beta [KO:K06752]
471979  
HLA class II histocompatibility antigen; K06752 major histocompatibility complex, class II [KO:K06752]
462591  
PATR-DRA; major histocompatibility complex, class II, DR alpha [KO:K06752]
462594  
PATR-DQB1; major histocompatibility complex, class II, DQ beta 1 [KO:K06752]
462598  
PATR-DPA1; major histocompatibility complex, class II, DP alpha 1 [KO:K06752]
462599  
PATR-DPB1; major histocompatibility complex, class II, DP beta 1 [KO:K06752]
462592  
PATR-DRB5; major histocompatibility complex, class II, DR beta 5 [KO:K06752]
HLA class II histocompatibility antigen; K06752 major histocompatibility complex, class II [KO:K06752]
MAMU-DMA; HLA class II histocompatibility antigen, DM alpha chain-like [KO:K06752]
462191  
CD74; CD74 molecule, major histocompatibility complex, class II invariant chain [KO:K06505]
737449  
CTSL1; cathepsin L1 [KO:K01365] [EC:3.4.22.15]
457277  
CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
450124  
CD4; CD4 molecule [KO:K06454]
453914  
CIITA; class II, major histocompatibility complex, transactivator [KO:K08060]
457292  
RFX5; regulatory factor X, 5 (influences HLA class II expression) [KO:K08061]
455872  
RFXANK; regulatory factor X-associated ankyrin-containing protein [KO:K08062]
RFXAP; regulatory factor X-associated protein [KO:K08063]
459901  
CREB1; cAMP responsive element binding protein 1 [KO:K05870]
748395  
NFYA; nuclear transcription factor Y, alpha [KO:K08064]
452191  
NFYB; nuclear transcription factor Y, beta [KO:K08065]
456799  
NFYC; nuclear transcription factor Y, gamma [KO:K08066]
464733  
HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [KO:K09490]
Reference
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
Reference
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
Reference
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
Reference
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
Reference
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
Reference
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
Reference
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
Reference
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
Reference
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
Reference
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
Reference
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
Reference
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
Reference
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
Reference
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
Reference
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
KO pathway
 

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