KEGG   PATHWAY: rme00230Help
Entry
rme00230                    Pathway                                
Name
Purine metabolism - Cupriavidus metallidurans
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
Purine metabolism
rme00230

All organismsOrtholog table
Module
PRPP biosynthesis, ribose 5P => PRPP [PATH:rme00230]
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:rme00230]
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rme00230]
Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:rme00230]
Purine degradation, xanthine => urea [PATH:rme00230]
Other DBs
BSID: 
GO: 
Organism
Cupriavidus metallidurans [GN:rme]
Gene
putative ADP-ribose pyrophosphatase; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
cpsG; phosphomannomutase [KO:K15778] [EC:5.4.2.2 5.4.2.8]
prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:2.1.2.2]
purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
surE; 5'(3')-nucleotidase/polyphosphatase [KO:K03787] [EC:3.1.3.5]
surE; 5'-nucleotidase [KO:K03787] [EC:3.1.3.5]
hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
guaB; inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
ndk; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase [KO:K00940] [EC:2.7.4.6]
yggV; dITP/XTP pyrophosphatase [KO:K02428] [EC:3.6.1.19]
xdhA; xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A [KO:K13481] [EC:1.17.1.4]
xdhB; xanthine dehydrogenase, subunit B [KO:K13482] [EC:1.17.1.4]
guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] [KO:K01951] [EC:6.3.5.2]
guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
pykA2; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
pykA1; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
pyk; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
nrdJ; ribonucleotide reductase, coenzyme B12-dependent [KO:K00525] [EC:1.17.4.1]
nrdA; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K00527] [EC:1.17.4.2]
dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
rpoA; DNA-directed RNA polymerase subunit alpha [KO:K03040] [EC:2.7.7.6]
rpoB; DNA-directed RNA polymerase subunit beta [KO:K03043] [EC:2.7.7.6]
rpoC; DNA-directed RNA polymerase subunit beta' [KO:K03046] [EC:2.7.7.6]
rpoZ; DNA-directed RNA polymerase subunit omega [KO:K03060] [EC:2.7.7.6]
polA; DNA polymerase I [KO:K02335] [EC:2.7.7.7]
dnaE; DNA polymerase III subunit alpha [KO:K02337] [EC:2.7.7.7]
dnaN; DNA polymerase III subunit beta [KO:K02338] [EC:2.7.7.7]
dnaX; DNA polymerase III subunits gamma and tau [KO:K02343] [EC:2.7.7.7]
holA; DNA polymerase III subunit delta [KO:K02340] [EC:2.7.7.7]
holB; DNA polymerase III subunit delta' [KO:K02341] [EC:2.7.7.7]
dnaQ; DNA polymerase III subunit epsilon [KO:K02342] [EC:2.7.7.7]
ydjQ; DNA polymerase III, epsilon subunit [KO:K02342] [EC:2.7.7.7]
holC; DNA polymerase III subunit chi [KO:K02339] [EC:2.7.7.7]
ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.40 3.6.1.11]
relA; (p)ppGpp synthetase I/GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
spoT; bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K00951] [EC:2.7.6.5]
purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
carbohydrate kinase; K00856 adenosine kinase [EC:2.7.1.20] [KO:K00856] [EC:2.7.1.20]
add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
cpdB; 2':3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16]
adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
pnp; polynucleotide phosphorylase/polyadenylase [KO:K00962] [EC:2.7.7.8]
apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
cysN; sulfate adenylyltransferase, subunit 1 [KO:K00956] [EC:2.7.7.4]
cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
transthyretin-like protein; K07127 5-hydroxyisourate hydrolase [EC:3.5.2.17] [KO:K07127] [EC:3.5.2.17]
hypothetical protein; K13485 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.-] [KO:K13485] [EC:4.1.1.-]
allantoate amidohydrolase; K02083 allantoate deiminase [EC:3.5.3.9] [KO:K02083] [EC:3.5.3.9]
ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  
ATP
C00008  
ADP
C00011  
CO2
C00014  
NH3
C00020  
AMP
C00035  
GDP
C00037  
Glycine
C00039  
DNA
C00044  
GTP
C00046  
RNA
C00048  
Glyoxylate
C00053  
3'-Phosphoadenylyl sulfate
C00054  
Adenosine 3',5'-bisphosphate
C00059  
Sulfate
C00064  
L-Glutamine
C00081  
ITP
C00086  
Urea
C00104  
IDP
C00117  
D-Ribose 5-phosphate
C00119  
5-Phospho-alpha-D-ribose 1-diphosphate
C00130  
IMP
C00131  
dATP
C00144  
GMP
C00147  
Adenine
C00169  
Carbamoyl phosphate
C00206  
dADP
C00212  
Adenosine
C00224  
Adenylyl sulfate
C00242  
Guanine
C00262  
Hypoxanthine
C00286  
dGTP
C00294  
Inosine
C00301  
ADP-ribose
C00330  
Deoxyguanosine
C00360  
dAMP
C00361  
dGDP
C00362  
dGMP
C00366  
Urate
C00385  
Xanthine
C00387  
Guanosine
C00499  
Allantoate
C00559  
Deoxyadenosine
C00575  
3',5'-Cyclic AMP
C00603  
(-)-Ureidoglycolate
C00620  
alpha-D-Ribose 1-phosphate
C00655  
Xanthosine 5'-phosphate
C00700  
XTP
C00802  
Oxalureate
C00942  
3',5'-Cyclic GMP
C01228  
Guanosine 3',5'-bis(diphosphate)
C01260  
P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261  
P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  
dIDP
C01345  
dITP
C01367  
3'-AMP
C01762  
Xanthosine
C02091  
(S)-Ureidoglycine
C02348  
(R)(-)-Allantoin
C02350  
(S)(+)-Allantoin
C02353  
2',3'-Cyclic AMP
C02718  
N-Formiminoglycine
C03090  
5-Phosphoribosylamine
C03373  
Aminoimidazole ribotide
C03483  
Adenosine tetraphosphate
C03614  
Inosine 5'-tetraphosphate
C03794  
N6-(1,2-Dicarboxyethyl)-AMP
C03838  
5'-Phosphoribosylglycinamide
C04051  
5-Amino-4-imidazolecarboxyamide
C04376  
5'-Phosphoribosyl-N-formylglycinamide
C04392  
P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  
Guanosine 3'-diphosphate 5'-triphosphate
C04640  
2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  
5-Aminoimidazole
C05512  
Deoxyinosine
C05513  
Urate-3-ribonucleoside
C05515  
5-Ureido-4-imidazole carboxylate
C05516  
5-Amino-4-imidazole carboxylate
C05993  
Acetyl adenylate
C06193  
Guanosine 3'-phosphate
C06194  
2',3'-Cyclic GMP
C06195  
Imidazolone
C06196  
2'-Deoxyinosine 5'-phosphate
C06197  
P1,P3-Bis(5'-adenosyl) triphosphate
C06433  
5'-Benzoylphosphoadenosine
C06435  
5'-Butyrylphosphoinosine
C11821  
5-Hydroxyisourate
C12248  
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
KO pathway
 
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