KEGG   PATHWAY: rn00630Help
Entry
rn00630                     Pathway                                

Name
Glyoxylate and dicarboxylate metabolism
Class
Metabolism; Carbohydrate metabolism
Pathway map
rn00630  Glyoxylate and dicarboxylate metabolism
rn00630

Ortholog table
Module
M00012  Glyoxylate cycle [PATH:rn00630]
M00373  Ethylmalonyl pathway [PATH:rn00630]
M00532  Photorespiration [PATH:rn00630]
M00740  Methylaspartate cycle [PATH:rn00630]
M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:rn00630]
Reaction
R00009  hydrogen-peroxide:hydrogen-peroxide oxidoreductase
R00013  glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)
R00021  L-glutamate:ferredoxin oxidoreductase (transaminating)
R00238  Acetyl-CoA:acetyl-CoA C-acetyltransferase
R00253  L-Glutamate:ammonia ligase (ADP-forming)
R00262  L-threo-3-methylaspartate carboxy-aminomethylmutase
R00273  oxalate:oxygen oxidoreductase
R00339  (R,R)-tartrate hydro-lyase (oxaloacetate-forming)
R00342  (S)-malate:NAD+ oxidoreductase
R00351  acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)
R00372  Glycine:2-oxoglutarate aminotransferase
R00465  glycolate:NADP+ oxidoreductase
R00466  Glyoxylate:oxygen oxidoreductase
R00468  Glyoxylate:NADP+ oxidoreductase (CoA-oxalylating)
R00470  4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)
R00472  acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R00473  L-malyl-CoA glyoxylate-lyase (acetyl-CoA-forming)
R00474  2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)
R00475  glycolate:oxygen 2-oxidoreductase
R00476  glycolate:acceptor 2-oxidoreductase
R00477  3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)
R00479  isocitrate glyoxylate-lyase (succinate-forming)
R00518  ATP:formate phosphotransferase
R00519  formate:NAD+ oxidoreductase
R00521  Formyl-CoA hydrolase
R00522  Oxalate carboxy-lyase
R00524  Formamide amidohydrolase
R00525  N-Formyl-L-glutamate amidohydrolase
R00526  N-Formyl-L-aspartate amidohydrolase
R00588  L-Serine:glyoxylate aminotransferase
R00653  N-Formyl-L-methionine amidohydrolase
R00717  Glycolate:NAD+ oxidoreductase
R00833  (R)-Methylmalonyl-CoA CoA-carbonylmutase
R00934  L-erythro-3-methylmalyl-CoA glyoxylate-lyase (propanoyl-CoA-forming)
R00944  10-Formyltetrahydrofolate amidohydrolase
R00945  5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
R01180  butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)
R01221  glycine synthase
R01256  (S)-malate:CoA ligase (ADP-forming)
R01325  citrate hydro-lyase (cis-aconitate-forming)
R01333  glycolaldehyde:NAD+ oxidoreductase
R01334  2-phosphoglycolate phosphohydrolase
R01388  D-Glycerate:NAD+ 2-oxidoreductase
R01390   
R01392  D-Glycerate:NADP+ 2-oxidoreductase
R01393  hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)
R01394  hydroxypyruvate aldose-ketose-isomerase
R01514  ATP:(R)-glycerate 3-phosphotransferase
R01558  oxalate:CoA ligase (AMP-forming)
R01559  Succinyl-CoA:oxalate CoA-transferase
R01745  (R)-Glycerate:NAD+ oxidoreductase
R01747  (R)-Glycerate:NADP+ oxidoreductase
R01749  D-Glycerate:NAD+ oxidoreductase (carboxylating)
R01750  D-Glycerate:NADP+ oxidoreductase (carboxylating)
R01781  1,2-Ethanediol:NAD+ oxidoreductase
R01859  propanoyl-CoA:carbon-dioxide ligase (ADP-forming)
R01900  isocitrate hydro-lyase (cis-aconitate-forming)
R01908  oxalyl-CoA carboxy-lyase (formyl-CoA-forming)
R01959  N-Formyl-L-kynurenine amidohydrolase
R01977  (R)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase
R02509  N,N-Dimethylformamide amidohydrolase
R02544  meso-tartrate:NAD+ oxidoreductase
R02545  meso-tartaric acid:NAD+ oxidoreductase
R02546  (R,R)-Tartrate epimerase
R02547  trans-2,3-Epoxysuccinate hydrolase
R02765  Methylmalonyl-CoA epimerase
R03027  (3R)-3-hydroxybutanoyl-CoA hydro-lyase
R03040  3-Propylmalate glyoxylate-lyase (CoA-pentanoylating)
R03127  Dihydroxyfumarate carboxy-lyase
R03128   
R03140  D-Ribulose 1,5-bisphosphate oxygenase
R03146  Formate:ferricytochrome-b1 oxidoreductase
R03696  L-threo-3-Methylaspartate ammonia-lyase
R05076  (2R,3S)-2-methylmalyl-CoA hydro-lyase (2-methylfumaryl-CoA-forming)
R06180   
R08572  ATP:(R)-glycerate 2-phosphotransferase
R09291  ethylmalonyl-CoA:NADP+ oxidoreductase (decarboxylating)
R09292  (2R)-ethylmalonyl-CoA CoA-carbonylmutase
R09293  (2S)-methylsuccinyl-CoA:electron-transfer flavoprotein oxidoreductase
R09979  (2S)-ethylmalonyl-CoA epimerase
R10612  (S)-malyl-CoA hydrolase
R10904  succinyl-CoA:mesaconate CoA-transferase
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
Reference
PMID:10978349 (EC5.3.1.22)
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilusinfluenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
KO pathway
ko00630   

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