KEGG   PATHWAY: rpi00623Help
Entry
rpi00623                    Pathway                                

Name
Toluene degradation - Ralstonia pickettii 12J
Class
Metabolism; Xenobiotics biodegradation and metabolism
BRITE hierarchy
Pathway map
rpi00623  Toluene degradation
rpi00623

Ortholog table
Other DBs
BSID: 73909
GO: 0042203
UMBBD: tol tol2 tsa dct
Organism
Ralstonia pickettii 12J [GN:rpi]
Gene
Rpic_4631  Phenol hydroxylase subunit [KO:K16249]
Rpic_4630  Phenol 2-monooxygenase [KO:K16243]
Rpic_4629  monooxygenase component MmoB/DmpM [KO:K16244]
Rpic_4628  methane/phenol/toluene hydroxylase [KO:K16242] [EC:1.14.13.-]
Rpic_4627  Phenol hydroxylase conserved region [KO:K16245]
Rpic_4626  Oxidoreductase FAD-binding domain protein [KO:K16246]
Rpic_4632  methane/phenol/toluene hydroxylase [KO:K15760] [EC:1.14.13.- 1.14.13.236]
Rpic_4633  Toluene-4-monooxygenase system B [KO:K15761] [EC:1.14.13.- 1.14.13.236]
Rpic_4634  Rieske (2Fe-2S) domain protein [KO:K15762]
Rpic_4635  monooxygenase component MmoB/DmpM [KO:K15763] [EC:1.14.13.- 1.14.13.236]
Rpic_4636  methane/phenol/toluene hydroxylase [KO:K15764] [EC:1.14.13.- 1.14.13.236]
Rpic_4637  Oxidoreductase FAD-binding domain protein [KO:K15765] [EC:1.18.1.3]
Rpic_1363  catechol 1,2-dioxygenase [KO:K03381] [EC:1.13.11.1]
Rpic_1361  muconate and chloromuconate cycloisomerase [KO:K01856] [EC:5.5.1.1]
Rpic_2433  Carboxymethylenebutenolidase [KO:K01061] [EC:3.1.1.45]
Rpic_4117  Carboxymethylenebutenolidase [KO:K01061] [EC:3.1.1.45]
Compound
C00091  Succinyl-CoA
C00156  4-Hydroxybenzoate
C00180  Benzoate
C00230  3,4-Dihydroxybenzoate
C00261  Benzaldehyde
C00512  Benzoyl-CoA
C00556  Benzyl alcohol
C00587  3-Hydroxybenzoate
C00633  4-Hydroxybenzaldehyde
C01455  Toluene
C01467  3-Cresol
C01468  4-Cresol
C01542  o-Cresol
C02236  4-Sulfobenzoate
C02923  2,3-Dihydroxytoluene
C03067  3-Hydroxybenzaldehyde
C03351  3-Hydroxybenzyl alcohol
C04112  3-Methyl-cis,cis-hexadienedioate
C04558  3-Methylmuconolactone
C04559  4-Methylmuconolactone
C04592  Toluene-cis-dihydrodiol
C06677  Toluene-4-sulfonate
C06678  4-Sulfobenzyl alcohol
C06679  4-Sulfobenzaldehyde
C06730  4-Methylcatechol
C09816  Benzylsuccinate
C09817  Benzylsuccinyl-CoA
C09818  E-Phenylitaconyl-CoA
C09819  (Hydroxymethylphenyl)succinyl-CoA
C09820  Benzoylsuccinyl-CoA
C14582  2,4-Dimethylphenol
C18300  2,4-Dichlorotoluene
C18301  4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene
C18302  4,6-Dichloro-3-methylcatechol
C18303  3,5-Dichloro-2-methylmuconate
C18304  2-Chloro-5-methyl-cis-dienelactone
C18305  2-Chloro-5-methylmaleylacetate
C18306  5-Methylmaleylacetate
C18307  2-Methyl-3-oxoadipate
C18308  3,5-Dichloro-2-methylmuconolactone
C18309  3-Chloro-2-methyldienelactone
C18310  3-Chloro-2-methylmaleylacetate
C18311  4-Methyl-3-oxoadipate-enol-lactone
C18312  4-Methyl-3-oxoadipate
C21166  4-Hydroxy-3-methylbenzaldehyde
C21167  4-Hydroxy-3-methylbenzoate
C21168  4-Hydroxyisophthalate
Reference
  Authors
Vardar G, Wood TK
  Title
Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for synthesizing 4-methylresorcinol, methylhydroquinone, and pyrogallol.
  Journal
Appl Environ Microbiol 70:3253-62 (2004)
DOI:10.1128/AEM.70.6.3253-3262.2004
Reference
  Authors
Leuthner B, Heider J
  Title
Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate.
  Journal
J Bacteriol 182:272-7 (2000)
DOI:10.1128/JB.182.2.272-277.2000
Reference
  Authors
Leutwein C, Heider J
  Title
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria.
  Journal
J Bacteriol 183:4288-95 (2001)
DOI:10.1128/JB.183.14.4288-4295.2001
Reference
  Authors
Kuhner S, Wohlbrand L, Fritz I, Wruck W, Hultschig C, Hufnagel P, Kube M, Reinhardt R, Rabus R
  Title
Substrate-dependent regulation of anaerobic degradation pathways for toluene and ethylbenzene in a denitrifying bacterium, strain EbN1.
  Journal
J Bacteriol 187:1493-503 (2005)
DOI:10.1128/JB.187.4.1493-1503.2005
Reference
PMID:2050632
  Authors
Locher HH, Leisinger T, Cook AM
  Title
4-Toluene sulfonate methyl-monooxygenase from Comamonas testosteroni T-2: purification and some properties of the oxygenase component.
  Journal
J Bacteriol 173:3741-8 (1991)
DOI:10.1128/JB.173.12.3741-3748.1991
Reference
PMID:8828208
  Authors
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM
  Title
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.
  Journal
Microbiology 142 ( Pt 9):2419-27 (1996)
DOI:10.1099/00221287-142-9-2419
Reference
  Authors
Mampel J, Ruff J, Junker F, Cook AM.
  Title
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.
  Journal
Microbiology 145 ( Pt 11):3255-64 (1999)
DOI:10.1099/00221287-145-11-3255
Reference
PMID:9006050
  Authors
Junker F, Kiewitz R, Cook AM
  Title
Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2.
  Journal
J Bacteriol 179:919-27 (1997)
DOI:10.1128/JB.179.3.919-927.1997
KO pathway
ko00623   

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