KEGG   PATHWAY: rsh00230
Entry
rsh00230                    Pathway                                
Name
Purine metabolism - Cereibacter sphaeroides ATCC 17029
Class
Metabolism; Nucleotide metabolism
Pathway map
rsh00230  Purine metabolism
rsh00230

Module
rsh_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rsh00230]
rsh_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rsh00230]
rsh_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rsh00230]
rsh_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rsh00230]
rsh_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rsh00230]
rsh_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rsh00230]
Other DBs
GO: 0006163 0042278
Organism
Cereibacter sphaeroides ATCC 17029 [GN:rsh]
Gene
Rsph17029_0249  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Rsph17029_1529  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K01835] [EC:5.4.2.2]
Rsph17029_0976  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Rsph17029_1117  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Rsph17029_0496  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Rsph17029_0678  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Rsph17029_1596  phosphoribosylformylglycinamidine synthase subunit II [KO:K23269] [EC:6.3.5.3]
Rsph17029_0802  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Rsph17029_0803  phosphoribosylformylglycinamidine synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Rsph17029_0677  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Rsph17029_0221  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
Rsph17029_0222  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Rsph17029_0801  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Rsph17029_0932  Phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Rsph17029_0897  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Rsph17029_2763  IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Rsph17029_0485  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Rsph17029_2615  5'-Nucleotidase domain protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Rsph17029_1205  5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Rsph17029_0882  purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
Rsph17029_0230  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Rsph17029_1428  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Rsph17029_1514  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Rsph17029_1538  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Rsph17029_2883  Ham1 family protein [KO:K01519] [EC:3.6.1.66]
Rsph17029_1017  Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Rsph17029_3237  molybdopterin dehydrogenase, FAD-binding [KO:K13481] [EC:1.17.1.4]
Rsph17029_3238  Xanthine oxidase [KO:K13482] [EC:1.17.1.4]
Rsph17029_3945  xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K11177] [EC:1.17.1.4]
Rsph17029_3944  molybdopterin dehydrogenase, FAD-binding [KO:K11178] [EC:1.17.1.4]
Rsph17029_3943  (2Fe-2S)-binding domain protein [KO:K13483]
Rsph17029_1635  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Rsph17029_0545  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Rsph17029_1563  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Rsph17029_1162  ribonucleoside-diphosphate reductase class II [KO:K00525] [EC:1.17.4.1]
Rsph17029_3230  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Rsph17029_1317  putative deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Rsph17029_0168  metal dependent phosphohydrolase [KO:K06952] [EC:3.1.3.89]
Rsph17029_0303  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Rsph17029_2438  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Rsph17029_1413  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Rsph17029_2010  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Rsph17029_0250  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Rsph17029_0054  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Rsph17029_2645  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
Rsph17029_2364  5'-Nucleotidase domain protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Rsph17029_2310  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
Rsph17029_0382  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Rsph17029_2231  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Rsph17029_1556  MazG family protein [KO:K04765] [EC:3.6.1.9]
Rsph17029_0227  adenylylsulfate kinase / sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
Rsph17029_0207  Transthyretin [KO:K07127] [EC:3.5.2.17]
Rsph17029_4060  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
Rsph17029_0206  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
Rsph17029_0205  protein of unknown function DUF861, cupin_3 [KO:K14977] [EC:3.5.3.26]
Rsph17029_0204  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Rsph17029_1950  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Rsph17029_1953  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Rsph17029_1954  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rsh00030  Pentose phosphate pathway
rsh00220  Arginine biosynthesis
rsh00250  Alanine, aspartate and glutamate metabolism
rsh00260  Glycine, serine and threonine metabolism
rsh00340  Histidine metabolism
rsh00630  Glyoxylate and dicarboxylate metabolism
rsh00730  Thiamine metabolism
rsh00740  Riboflavin metabolism
rsh00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (59)   
   KEGG GENES (59)   
All databases (60)   

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