KEGG   PATHWAY: sbc00053
Entry
sbc00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Shigella boydii CDC 3083-94 (serotype 18)
Class
Metabolism; Carbohydrate metabolism
Pathway map
sbc00053  Ascorbate and aldarate metabolism
sbc00053

Other DBs
GO: 0019852 0019577 0019572
Organism
Shigella boydii CDC 3083-94 (serotype 18) [GN:sbc]
Gene
SbBS512_E1203  UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
SbBS512_E1804  uidA; beta-glucuronidase UidA [KO:K01195] [EC:3.2.1.31]
SbBS512_E1204  NAD dependent epimerase/dehydratase family [KO:K08679] [EC:5.1.3.6]
SbBS512_E4898  oxidoreductase, zinc-binding dehydrogenase family [KO:K23007] [EC:1.1.1.414]
SbBS512_E4725  ulaC; ascorbate-specific phosphotransferase enzyme IIA component [KO:K02821] [EC:2.7.1.194]
SbBS512_E4724  ulaB; ascorbate-specific phosphotransferase enzyme IIB component [KO:K02822] [EC:2.7.1.194]
SbBS512_E4722  putative L-ascorbate-6-phosphate lactonase ulaG [KO:K03476] [EC:3.1.1.-]
SbBS512_E4726  orotidine 5'-phosphate decarboxylase / HUMPS family [KO:K03078] [EC:4.1.1.85]
SbBS512_E4727  ulaE; L-ribulose-5-phosphate 3-epimerase [KO:K03079] [EC:5.1.3.22]
SbBS512_E4728  ulaF; L-ribulose-5-phosphate 4-epimerase [KO:K03077] [EC:5.1.3.4]
SbBS512_E0053  araD; L-ribulose-5-phosphate 4-epimerase [KO:K03077] [EC:5.1.3.4]
SbBS512_E3947  dlgD; 3-dehydro-L-gulonate 2-dehydrogenase [KO:K08092] [EC:1.1.1.130]
SbBS512_E3086  glucarate dehydratase [KO:K01706] [EC:4.2.1.40]
SbBS512_E3232  hpcH/hpaI aldolase family [KO:K01630] [EC:4.1.2.20]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
sbc00020  Citrate cycle (TCA cycle)
sbc00040  Pentose and glucuronate interconversions
sbc00051  Fructose and mannose metabolism
sbc00520  Amino sugar and nucleotide sugar metabolism
sbc00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG GENES (14)   
All databases (15)   

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