KEGG   PATHWAY: sen00620
Entry
sen00620                    Pathway                                
Name
Pyruvate metabolism - Saccharopolyspora erythraea
Class
Metabolism; Carbohydrate metabolism
Pathway map
sen00620  Pyruvate metabolism
sen00620

Module
sen_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sen00620]
Other DBs
GO: 0006090
Organism
Saccharopolyspora erythraea [GN:sen]
Gene
SACE_2375  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SACE_2408  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SACE_0337  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SACE_4729  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SACE_3902  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
SACE_3927  korA; 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit [KO:K00174] [EC:1.2.7.3 1.2.7.11]
SACE_3926  2-oxoglutarate ferredoxin oxidoreductase, beta subunit [KO:K00175] [EC:1.2.7.3 1.2.7.11]
SACE_1532  aceE; pyruvate dehydrogenase E1 component [KO:K00163] [EC:1.2.4.1]
SACE_2407  phdB; probable pyruvate dehydrogenase E1 component,alpha subunit [KO:K00161] [EC:1.2.4.1]
SACE_5676  pyruvate dehydrogenase (lipoamide) [KO:K00161] [EC:1.2.4.1]
SACE_2406  phdB; probable pyruvate dehydrogenase E1 component,beta subunit [KO:K00162] [EC:1.2.4.1]
SACE_5675  dehydrogenase complex, E1 component, beta subunit [KO:K00162] [EC:1.2.4.1]
SACE_2405  probable pyruvate dehydrogenase, E2 component,dihydrolipoamide acetyltransferase [KO:K00627] [EC:2.3.1.12]
SACE_4756  acoC; acetoin dehydrogenase, dihydrolipoamide acetyltransferase component [KO:K00627] [EC:2.3.1.12]
SACE_5674  pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase [KO:K00627] [EC:2.3.1.12]
SACE_1638  sucB; dihydrolipoamide succinyltransferase [KO:K00627] [EC:2.3.1.12]
SACE_1639  dldH2; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
SACE_5677  pdhD; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SACE_2374  alcohol dehydrogenase, zinc-binding [KO:K13953] [EC:1.1.1.1]
SACE_2738  alcohol dehydrogenase GroES-like protein [KO:K13953] [EC:1.1.1.1]
SACE_2733  alcohol dehydrogenase, zinc-binding [KO:K13953] [EC:1.1.1.1]
SACE_4519  alcohol dehydrogenase GroES-like [KO:K13953] [EC:1.1.1.1]
SACE_1946  putative alcohol dehydrogenase (zinc-binding) [KO:K00121] [EC:1.1.1.284 1.1.1.1]
SACE_1843  adhA; NADP-dependent alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
SACE_2652  alcohol dehydrogenase, zinc-binding [KO:K13979] [EC:1.1.1.2]
SACE_4449  exaA; probable quinoprotein ethanol dehydrogenase precursor [KO:K00114] [EC:1.1.2.8]
SACE_1922  ackA; acetate/propionate kinase [KO:K00925] [EC:2.7.2.1]
SACE_5720  pyk3; pyruvate kinase [KO:K00873] [EC:2.7.1.40]
SACE_0027  acetyl-CoA carboxylase, biotin carboxyl carrier protein [KO:K02160]
SACE_6428  biotin/lipoyl attachment [KO:K02160]
SACE_5182  acetyl-CoA carboxylase [KO:K02160]
SACE_0028  acetyl-CoA carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
SACE_6509  acetyl/propionyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SACE_3400  acetyl/propionyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SACE_6072  acyP; acylphosphatase [KO:K01512] [EC:3.6.1.7]
SACE_1341  aldA; aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SACE_6565  Betaine-aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SACE_2895  betaine-aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SACE_3969  betaine-aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
SACE_4926  putative betaine aldehyde dehydrogenase oxidoreductase protein [KO:K00128] [EC:1.2.1.3]
SACE_2915  thcA; aldehyde dehydrogenase (NAD+) [KO:K00138] [EC:1.2.1.-]
SACE_2377  thcA; aldehyde dehydrogenase (NAD+) [KO:K00138] [EC:1.2.1.-]
SACE_5861  aarC; acetyl-CoA hydrolase/transferase [KO:K18118] [EC:2.8.3.18]
SACE_5887  lldD2; L-lactate dehydrogenase [KO:K00101] [EC:1.1.2.3]
SACE_4311  lldD2; L-lactate dehydrogenase [KO:K00101] [EC:1.1.2.3]
SACE_1218  poxB; pyruvate dehydrogenase [KO:K00156] [EC:1.2.5.1]
SACE_5551  poxB; pyruvate dehydrogenase [KO:K00156] [EC:1.2.5.1]
SACE_2627  idiB_2; isopentenyl-diphosphate delta-isomerase II 2 [KO:K00467] [EC:1.13.12.4]
SACE_6523  lactate 2-monooxygenase [KO:K00467] [EC:1.13.12.4]
SACE_2031  beta-lactamase-like protein [KO:K01069] [EC:3.1.2.6]
SACE_2429  beta-lactamase-like protein [KO:K01069] [EC:3.1.2.6]
SACE_5797  beta-lactamase-like protein [KO:K01069] [EC:3.1.2.6]
SACE_0563  malate dehydrogenase (oxaloacetate-decarboxylating) [KO:K00027] [EC:1.1.1.38]
SACE_6415  malate dehydrogenase (oxaloacetate decarboxylating) [KO:K00027] [EC:1.1.1.38]
SACE_6118  pyc; pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
SACE_3674  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SACE_1784  fumB; fumarate hydratase class I [KO:K01676] [EC:4.2.1.2]
SACE_0930  fumC; fumarase C (fumarate hydratase class II) [KO:K01679] [EC:4.2.1.2]
SACE_7274  pckA; phosphoenolpyruvate carboxykinase (GTP) [KO:K01596] [EC:4.1.1.32]
SACE_2459  phosphoenolpyruvate synthase (pyruvate, water dikinase) [KO:K01007] [EC:2.7.9.2]
SACE_6756  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
SACE_1192  mmgA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACE_2736  fadA6; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACE_7304  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACE_6236  fadA4; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACE_6363  fadA; acetyl CoA acetyltransferase (thiolase) [KO:K00626] [EC:2.3.1.9]
SACE_4011  catF; acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACE_0897  fadA3; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SACE_0274  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
SACE_6151  leuA2; 2-isopropylmalate synthase 2 [KO:K01649] [EC:2.3.3.13]
SACE_5707  leuA2; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
sen00010  Glycolysis / Gluconeogenesis
sen00020  Citrate cycle (TCA cycle)
sen00061  Fatty acid biosynthesis
sen00250  Alanine, aspartate and glutamate metabolism
sen00260  Glycine, serine and threonine metabolism
sen00290  Valine, leucine and isoleucine biosynthesis
sen00300  Lysine biosynthesis
sen00522  Biosynthesis of 12-, 14- and 16-membered macrolides
sen00630  Glyoxylate and dicarboxylate metabolism
sen00640  Propanoate metabolism
sen00650  Butanoate metabolism
sen00760  Nicotinate and nicotinamide metabolism
sen01059  Biosynthesis of enediyne antibiotics
KO pathway
ko00620   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (71)   
   KEGG GENES (71)   
All databases (72)   

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