KEGG   PATHWAY: sex00350Help
Entry
sex00350                    Pathway                                
Name
Tyrosine metabolism - Salmonella enterica subsp. enterica serovar Typhi P-stx-12
Class
Metabolism; Amino acid metabolism
BRITE hierarchy
Pathway map
Tyrosine metabolism
sex00350

All organismsOrtholog table
Module
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:sex00350]
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:sex00350]
Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:sex00350]
Other DBs
BSID: 
GO: 
Organism
Salmonella enterica subsp. enterica serovar Typhi P-stx-12 [GN:sex]
Gene
histidinol-phosphate aminotransferase; K00817 histidinol-phosphate aminotransferase [EC:2.6.1.9] [KO:K00817] [EC:2.6.1.9]
aromatic-amino-acid aminotransferase; K00832 aromatic-amino-acid transaminase [EC:2.6.1.57] [KO:K00832] [EC:2.6.1.57]
pyruvate-formate-lyase deactivase; K04072 acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] [KO:K04072] [EC:1.1.1.1 1.2.1.10]
alcohol dehydrogenase; K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] [KO:K13953] [EC:1.1.1.1]
4-hydroxyphenylacetate 3-monooxygenase oxygenase component; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] [KO:K00483] [EC:1.14.14.9]
4-hydroxyphenylacetate 3-monooxygenase reductase component; K00484 flavin reductase (NADH) [EC:1.5.1.36] [KO:K00484] [EC:1.5.1.36]
3; K00455 3,4-dihydroxyphenylacetate 2,3-dioxygenase [EC:1.13.11.15] [KO:K00455] [EC:1.13.11.15]
5-carboxymethyl-2-hydroxymuconate delta-isomerase; K01826 5-carboxymethyl-2-hydroxymuconate isomerase [EC:5.3.3.10] [KO:K01826] [EC:5.3.3.10]
5-carboxymethyl-2-oxo-hex-3-ene-1; K05921 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase [EC:4.1.1.68 5.3.3.-] [KO:K05921] [EC:5.3.3.- 4.1.1.68]
2-oxo-hepta-3-ene-1; K02509 2-oxo-hept-3-ene-1,7-dioate hydratase [EC:4.2.1.-] [KO:K02509] [EC:4.2.1.-]
4-hydroxy-2-oxo-heptane-1; K02510 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [EC:4.1.2.-] [KO:K02510] [EC:4.1.2.-]
succinate semialdehyde dehydrogenase; K00135 succinate-semialdehyde dehydrogenase (NADP+) [EC:1.2.1.16] [KO:K00135] [EC:1.2.1.16]
Gentisate 1; K00450 gentisate 1,2-dioxygenase [EC:1.13.11.4] [KO:K00450] [EC:1.13.11.4]
maleylacetoacetate isomerase; K01801 maleylpyruvate isomerase [EC:5.2.1.4] [KO:K01801] [EC:5.2.1.4]
Fumarylacetoacetate (FAA) hydrolase; K16165 fumarylpyruvate hydrolase [EC:3.7.1.20] [KO:K16165] [EC:3.7.1.20]
Compound
C00022  
Pyruvate
C00042  
Succinate
C00082  
L-Tyrosine
C00122  
Fumarate
C00146  
Phenol
C00164  
Acetoacetate
C00232  
Succinate semialdehyde
C00355  
3,4-Dihydroxy-L-phenylalanine
C00483  
Tyramine
C00530  
Hydroquinone
C00544  
Homogentisate
C00547  
L-Noradrenaline
C00628  
2,5-Dihydroxybenzoate
C00642  
4-Hydroxyphenylacetate
C00788  
L-Adrenaline
C00822  
Dopaquinone
C01036  
4-Maleylacetoacetate
C01060  
3,5-Diiodo-L-tyrosine
C01061  
4-Fumarylacetoacetate
C01161  
3,4-Dihydroxyphenylacetate
C01179  
3-(4-Hydroxyphenyl)pyruvate
C01207  
3-(3,4-Dihydroxyphenyl)lactate
C01693  
L-Dopachrome
C01829  
Thyroxine
C01850  
Rosmarinate
C02167  
Maleylpyruvate
C02442  
N-Methyltyramine
C02465  
Triiodothyronine
C02514  
3-Fumarylpyruvate
C02515  
3-Iodo-L-tyrosine
C03063  
2-Oxohept-3-enedioate
C03077  
4-Chlorophenylacetate
C03672  
3-(4-Hydroxyphenyl)lactate
C03758  
Dopamine
C03765  
4-Hydroxyphenylacetaldehyde
C04043  
3,4-Dihydroxyphenylacetaldehyde
C04045  
3-(3,4-Dihydroxyphenyl)pyruvate
C04052  
5-Carboxy-2-oxohept-3-enedioate
C04185  
5,6-Dihydroxyindole-2-carboxylate
C04186  
5-Carboxymethyl-2-hydroxymuconate
C04368  
3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  
2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  
4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  
5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  
4-Hydroxyphenylacetyl-CoA
C05350  
2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  
3,4-Dihydroxyphenylethyleneglycol
C05577  
3,4-Dihydroxymandelaldehyde
C05578  
5,6-Dihydroxyindole
C05579  
Indole-5,6-quinone
C05580  
3,4-Dihydroxymandelate
C05581  
3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  
Homovanillate
C05583  
3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  
3-Methoxy-4-hydroxymandelate
C05585  
Gentisate aldehyde
C05587  
3-Methoxytyramine
C05588  
L-Metanephrine
C05589  
L-Normetanephrine
C05593  
3-Hydroxyphenylacetate
C05594  
3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  
4-Hydroxyphenylacetylglutamic acid
C05596  
p-Hydroxyphenylacetylglycine
C05600  
2-Hydroxyhepta-2,4-dienedioate
C05604  
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  
4-Hydroxyphenylethanol
C06046  
Salidroside
C06047  
Stizolobate
C06048  
Stizolobinate
C06199  
Hordenine
C06201  
2,4-Dihydroxyhept-2-enedioate
C10447  
3,4-Dihydroxyphenylpropanoate
C17935  
Cysteinyldopa
C17936  
Phaeomelanin
C17937  
Eumelanin
C17938  
5,6-Indolequinone-2-carboxylic acid
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
Reference
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
Reference
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
KO pathway
 
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