KEGG   PATHWAY: sgr00630
Entry
sgr00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces griseus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sgr00630  Glyoxylate and dicarboxylate metabolism
sgr00630

Module
sgr_M00012  Glyoxylate cycle [PATH:sgr00630]
sgr_M00621  Glycine cleavage system [PATH:sgr00630]
sgr_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sgr00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces griseus [GN:sgr]
Gene
SGR_1643  putative isocitrate lyase [KO:K01637] [EC:4.1.3.1]
SGR_3326  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SGR_1334  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SGR_1644  aceB2; putative malate synthase [KO:K01638] [EC:2.3.3.9]
SGR_1297  aceB; putative malate synthase [KO:K01638] [EC:2.3.3.9]
SGR_2711  putative malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SGR_1691  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
SGR_1692  putative citrate synthase-like protein [KO:K01647] [EC:2.3.3.1]
SGR_4826  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
SGR_3076  putative citrate synthase [KO:K01647] [EC:2.3.3.1]
SGR_1506  putative aconitase [KO:K01681] [EC:4.2.1.3]
SGR_2138  putative acetoacetyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
SGR_5170  putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SGR_4215  putative ketoacyl CoA thiolase [KO:K00626] [EC:2.3.1.9]
SGR_4450  putative thiolase [KO:K00626] [EC:2.3.1.9]
SGR_5494  putative thiolase [KO:K00626] [EC:2.3.1.9]
SGR_6835  putative nonspecific lipid-transfer protein [KO:K00626] [EC:2.3.1.9]
SGR_994  putative acyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
SGR_1380  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SGR_2139  conserved hypothetical protein [KO:K05606] [EC:5.1.99.1]
SGR_1171  putative methylmalonyl-CoA mutase alpha subunit [KO:K14447] [EC:5.4.99.63]
SGR_3093  putative acetyl/propionyl CoA carboxylase alpha subunit [KO:K01965] [EC:6.4.1.3]
SGR_2616  putative acyl-CoA carboxylase beta subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
SGR_2621  putative acyl-CoA carboxylase alpha subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SGR_6745  putative methylmalonyl-CoA mutase alpha subunit [KO:K01847] [EC:5.4.99.2]
SGR_6746  putative methylmalonyl-CoA mutase beta subunit [KO:K01847] [EC:5.4.99.2]
SGR_4614  putative oxidoreductase [KO:K00104] [EC:1.1.99.14]
SGR_2316  putative catalase [KO:K03781] [EC:1.11.1.6]
SGR_1323  putative catalase [KO:K03781] [EC:1.11.1.6]
SGR_1958  putative catalase [KO:K03781] [EC:1.11.1.6]
SGR_3178  putative hydrolase [KO:K01091] [EC:3.1.3.18]
SGR_5264  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SGR_5302  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SGR_5315  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SGR_6473  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SGR_2047  putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SGR_2172  putative serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SGR_2593  putative glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SGR_6151  putative glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SGR_2045  putative glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
SGR_5330  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SGR_2046  putative glycine cleavage system protein H [KO:K02437]
SGR_1329  putative glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
SGR_1321  putative oxidoreductase [KO:K01816] [EC:5.3.1.22]
SGR_1322  putative dehydrogenase [KO:K00042] [EC:1.1.1.60]
SGR_1188  putative glycerate kinase [KO:K00865] [EC:2.7.1.165]
SGR_5115  putative glycerate kinase [KO:K00865] [EC:2.7.1.165]
SGR_5216  putative KDPG and KHG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SGR_2226  putative 2-oxoglutarate dehydrogenase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
SGR_3063  putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sgr00010  Glycolysis / Gluconeogenesis
sgr00020  Citrate cycle (TCA cycle)
sgr00030  Pentose phosphate pathway
sgr00053  Ascorbate and aldarate metabolism
sgr00071  Fatty acid degradation
sgr00230  Purine metabolism
sgr00250  Alanine, aspartate and glutamate metabolism
sgr00260  Glycine, serine and threonine metabolism
sgr00620  Pyruvate metabolism
sgr00750  Vitamin B6 metabolism
sgr00910  Nitrogen metabolism
KO pathway
ko00630   

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