KEGG   PATHWAY: smd00630Help
Entry
smd00630                    Pathway                                

Name
Glyoxylate and dicarboxylate metabolism - Sinorhizobium medicae
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
Glyoxylate and dicarboxylate metabolism
smd00630

All organismsOrtholog table
Module
Glyoxylate cycle [PATH:smd00630]
Organism
Sinorhizobium medicae [GN:smd]
Gene
isocitrate lyase; K01637 isocitrate lyase [EC:4.1.3.1] [KO:K01637] [EC:4.1.3.1]
malate synthase G; K01638 malate synthase [EC:2.3.3.9] [KO:K01638] [EC:2.3.3.9]
malate dehydrogenase; K00024 malate dehydrogenase [EC:1.1.1.37] [KO:K00024] [EC:1.1.1.37]
gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
aconitate hydratase; K01681 aconitate hydratase [EC:4.2.1.3] [KO:K01681] [EC:4.2.1.3]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
beta-ketoadipyl CoA thiolase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]
acetoacetyl-CoA reductase; K00023 acetoacetyl-CoA reductase [EC:1.1.1.36] [KO:K00023] [EC:1.1.1.36]
methylmalonyl-CoA epimerase; K05606 methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] [KO:K05606] [EC:5.1.99.1]
carbamoyl-phosphate synthase L chain ATP-binding; K01965 propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] [KO:K01965] [EC:6.4.1.3]
carboxyl transferase; K01966 propionyl-CoA carboxylase beta chain [EC:6.4.1.3] [KO:K01966] [EC:6.4.1.3]
methylmalonyl-CoA mutase; K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] [KO:K01847] [EC:5.4.99.2]
D-lactate dehydrogenase; K00104 glycolate oxidase [EC:1.1.3.15] [KO:K00104] [EC:1.1.3.15]
FAD linked oxidase domain-containing protein; K11472 glycolate oxidase FAD binding subunit [KO:K11472]
hypothetical protein; K11473 glycolate oxidase iron-sulfur subunit [KO:K11473]
catalase; K03781 catalase [EC:1.11.1.6] [KO:K03781] [EC:1.11.1.6]
catalase; K03781 catalase [EC:1.11.1.6] [KO:K03781] [EC:1.11.1.6]
HAD family hydrolase; K01091 phosphoglycolate phosphatase [EC:3.1.3.18] [KO:K01091] [EC:3.1.3.18]
phosphoglycolate phosphatase; K01091 phosphoglycolate phosphatase [EC:3.1.3.18] [KO:K01091] [EC:3.1.3.18]
HAD family hydrolase; K01091 phosphoglycolate phosphatase [EC:3.1.3.18] [KO:K01091] [EC:3.1.3.18]
RuBisCO-like protein; K01601 ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39] [KO:K01601] [EC:4.1.1.39]
rbcL; ribulose bisophosphate carboxylase [KO:K01601] [EC:4.1.1.39]
ribulose-bisphosphate carboxylase; K01602 ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39] [KO:K01602] [EC:4.1.1.39]
Serine--pyruvate transaminase; K00830 alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51] [KO:K00830] [EC:2.6.1.51 2.6.1.45 2.6.1.44]
glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamine synthetase catalytic region; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamate--ammonia ligase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamate--putrescine ligase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamine synthetase catalytic region; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]
glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
glycine cleavage system protein H; K02437 glycine cleavage system H protein [KO:K02437]
glyoxylate carboligase; K01608 tartronate-semialdehyde synthase [EC:4.1.1.47] [KO:K01608] [EC:4.1.1.47]
hydroxypyruvate isomerase; K01816 hydroxypyruvate isomerase [EC:5.3.1.22] [KO:K01816] [EC:5.3.1.22]
hydroxypyruvate isomerase; K01816 hydroxypyruvate isomerase [EC:5.3.1.22] [KO:K01816] [EC:5.3.1.22]
hydroxypyruvate isomerase; K01816 hydroxypyruvate isomerase [EC:5.3.1.22] [KO:K01816] [EC:5.3.1.22]
2-hydroxy-3-oxopropionate reductase; K00042 2-hydroxy-3-oxopropionate reductase [EC:1.1.1.60] [KO:K00042] [EC:1.1.1.60]
2-hydroxy-3-oxopropionate reductase; K00042 2-hydroxy-3-oxopropionate reductase [EC:1.1.1.60] [KO:K00042] [EC:1.1.1.60]
2-hydroxy-3-oxopropionate reductase; K00042 2-hydroxy-3-oxopropionate reductase [EC:1.1.1.60] [KO:K00042] [EC:1.1.1.60]
glyoxylate reductase; K00015 glyoxylate reductase [EC:1.1.1.26] [KO:K00015] [EC:1.1.1.26]
hydroxypyruvate reductase; K00050 hydroxypyruvate reductase [EC:1.1.1.81] [KO:K00050] [EC:1.1.1.81]
hydroxypyruvate reductase; K00050 hydroxypyruvate reductase [EC:1.1.1.81] [KO:K00050] [EC:1.1.1.81]
NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; K12972 gyoxylate/hydroxypyruvate reductase A [EC:1.1.1.79 1.1.1.81] [KO:K12972] [EC:1.1.1.81 1.1.1.79]
NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; K12972 gyoxylate/hydroxypyruvate reductase A [EC:1.1.1.79 1.1.1.81] [KO:K12972] [EC:1.1.1.81 1.1.1.79]
aldehyde dehydrogenase; K07248 lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21] [KO:K07248] [EC:1.2.1.21 1.2.1.22]
3-isopropylmalate dehydrogenase; K07246 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase [EC:1.1.1.93 4.1.1.73 1.1.1.83] [KO:K07246] [EC:1.1.1.83 4.1.1.73 1.1.1.93]
keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; K01625 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] [KO:K01625] [EC:4.1.3.42 4.1.2.14]
2-dehydro-3-deoxyphosphogluconate aldolase; K01625 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] [KO:K01625] [EC:4.1.3.42 4.1.2.14]
putative NAD-dependent formate dehydrogenase subunit delta; K00126 formate dehydrogenase subunit delta [EC:1.2.1.2] [KO:K00126] [EC:1.2.1.2]
formate dehydrogenase subunit alpha; K00123 formate dehydrogenase major subunit [EC:1.2.1.2] [KO:K00123] [EC:1.2.1.2]
molybdopterin oxidoreductase; K00123 formate dehydrogenase major subunit [EC:1.2.1.2] [KO:K00123] [EC:1.2.1.2]
NADH dehydrogenase (quinone); K00124 formate dehydrogenase iron-sulfur subunit [KO:K00124]
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; K00124 formate dehydrogenase iron-sulfur subunit [KO:K00124]
formate dehydrogenase; K00127 formate dehydrogenase subunit gamma [KO:K00127]
formate dehydrogenase subunit gamma; K00127 formate dehydrogenase subunit gamma [KO:K00127]
purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
formyltetrahydrofolate deformylase; K01433 formyltetrahydrofolate deformylase [EC:3.5.1.10] [KO:K01433] [EC:3.5.1.10]
formyltetrahydrofolate deformylase; K01433 formyltetrahydrofolate deformylase [EC:3.5.1.10] [KO:K01433] [EC:3.5.1.10]
Compound
C00007  
Oxygen
C00011  
CO2
C00014  
Ammonia
C00022  
Pyruvate
C00024  
Acetyl-CoA
C00025  
L-Glutamate
C00026  
2-Oxoglutarate
C00027  
Hydrogen peroxide
C00036  
Oxaloacetate
C00037  
Glycine
C00042  
Succinate
C00048  
Glyoxylate
C00058  
Formate
C00064  
L-Glutamine
C00065  
L-Serine
C00091  
Succinyl-CoA
C00100  
Propanoyl-CoA
C00136  
Butanoyl-CoA
C00149  
(S)-Malate
C00158  
Citrate
C00160  
Glycolate
C00168  
Hydroxypyruvate
C00197  
3-Phospho-D-glycerate
C00209  
Oxalate
C00258  
D-Glycerate
C00266  
Glycolaldehyde
C00311  
Isocitrate
C00313  
Oxalyl-CoA
C00332  
Acetoacetyl-CoA
C00417  
cis-Aconitate
C00552  
meso-Tartaric acid
C00683  
(S)-Methylmalonyl-CoA
C00798  
Formyl-CoA
C00877  
Crotonoyl-CoA
C00888  
Pentanoyl-CoA
C00898  
(R,R)-Tartaric acid
C00975  
Dihydroxyfumarate
C00988  
2-Phosphoglycolate
C01127  
4-Hydroxy-2-oxoglutarate
C01146  
2-Hydroxy-3-oxopropanoate
C01182  
D-Ribulose 1,5-bisphosphate
C01213  
(R)-Methylmalonyl-CoA
C01380  
Ethylene glycol
C01989  
3-Ethylmalate
C01990  
3-Oxalomalate
C02123  
3-Propylmalate
C02405  
Formyl phosphate
C03217  
2-Hydroxy-3-oxoadipate
C03459  
2-Hydroxy-3-oxosuccinate
C03548  
trans-2,3-Epoxysuccinate
C03561  
(R)-3-Hydroxybutanoyl-CoA
C04348  
L-Malyl-CoA
C06027  
L-erythro-3-Methylmalyl-CoA
C06028  
Mesaconyl-CoA
C06049  
N-Formylderivatives
C18026  
(2S)-Ethylmalonyl-CoA
C18324  
(2S)-Methylsuccinyl-CoA
C20238  
(2R)-Ethylmalonyl-CoA
Reference
PMID:10978349 (EC5.3.1.22)
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta -hydroxyacid dehydrogenases in Escherichia coli and Haemophilusinfluenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
KO pathway
 

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