Arginine and proline metabolism

Proline biosynthesis, glutamate => proline [PATH:srs00330]

Ornithine biosynthesis, glutamate => ornithine [PATH:srs00330]

Urea cycle [PATH:srs00330]

Creatine pathway [PATH:srs00330]

Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:srs00330]

Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:srs00330]

GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:srs00330]

GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:srs00330]

cytosine deaminase; K01485 cytosine deaminase [EC:3.5.4.1] [KO:K01485] [EC:3.5.4.1]

biosynthetic arginine decarboxylase; K01585 arginine decarboxylase [EC:4.1.1.19] [KO:K01585] [EC:4.1.1.19]

Agmatinase; K01480 agmatinase [EC:3.5.3.11] [KO:K01480] [EC:3.5.3.11]

Ornithine decarboxylase; K01581 ornithine decarboxylase [EC:4.1.1.17] [KO:K01581] [EC:4.1.1.17]

spermidine synthase; K00797 spermidine synthase [EC:2.5.1.16] [KO:K00797] [EC:2.5.1.16]

S-adenosylmethionine decarboxylase; K01611 S-adenosylmethionine decarboxylase [EC:4.1.1.50] [KO:K01611] [EC:4.1.1.50]

fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; K00316 spermidine dehydrogenase [EC:1.5.99.6] [KO:K00316] [EC:1.5.99.6]

aldehyde dehydrogenase; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] [KO:K00128] [EC:1.2.1.3]

diamine N-acetyltransferase; K00657 diamine N-acetyltransferase [EC:2.3.1.57] [KO:K00657] [EC:2.3.1.57]

arginine N-succinyltransferase; K00673 arginine N-succinyltransferase [EC:2.3.1.109] [KO:K00673] [EC:2.3.1.109]

N-succinylarginine dihydrolase; K01484 succinylarginine dihydrolase [EC:3.5.3.23] [KO:K01484] [EC:3.5.3.23]

acetylornithine/succinyldiaminopimelate aminotransferase; K00840 succinylornithine aminotransferase [EC:2.6.1.81] [KO:K00840] [EC:2.6.1.81]

N-succinylglutamate 5-semialdehyde dehydrogenase; K06447 succinylglutamic semialdehyde dehydrogenase [EC:1.2.1.71] [KO:K06447] [EC:1.2.1.71]

succinylglutamate desuccinylase; K05526 succinylglutamate desuccinylase [EC:3.5.1.96] [KO:K05526] [EC:3.5.1.96]

glutamate--putrescine ligase; K09470 gamma-glutamylputrescine synthase [EC:6.3.1.11] [KO:K09470] [EC:6.3.1.11]

glutamate--putrescine ligase; K09470 gamma-glutamylputrescine synthase [EC:6.3.1.11] [KO:K09470] [EC:6.3.1.11]

FAD dependent oxidoreductase; K09471 gamma-glutamylputrescine oxidase [EC:1.4.3.-] [KO:K09471] [EC:1.4.3.-]

FAD dependent oxidoreductase; K09471 gamma-glutamylputrescine oxidase [EC:1.4.3.-] [KO:K09471] [EC:1.4.3.-]

FAD dependent oxidoreductase; K09471 gamma-glutamylputrescine oxidase [EC:1.4.3.-] [KO:K09471] [EC:1.4.3.-]

aldehyde dehydrogenase; K09472 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [EC:1.2.1.-] [KO:K09472] [EC:1.2.1.-]

gamma-glutamyl-gamma-aminobutyrate hydrolase; K09473 gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94] [KO:K09473] [EC:3.5.1.94]

coenzyme F420-dependent NADP oxidoreductase; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] [KO:K00286] [EC:1.5.1.2]

pyrroline-5-carboxylate reductase; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] [KO:K00286] [EC:1.5.1.2]

delta-1-pyrroline-5-carboxylate dehydrogenase; K13821 proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.99.8 1.5.1.12] [KO:K13821] [EC:1.5.1.12 1.5.99.8]

ornithine cyclodeaminase; K01750 ornithine cyclodeaminase [EC:4.3.1.12] [KO:K01750] [EC:4.3.1.12]

glutamate 5-kinase; K00931 glutamate 5-kinase [EC:2.7.2.11] [KO:K00931] [EC:2.7.2.11]

gamma-glutamyl phosphate reductase; K00147 glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] [KO:K00147] [EC:1.2.1.41]

proline iminopeptidase; K01259 proline iminopeptidase [EC:3.4.11.5] [KO:K01259] [EC:3.4.11.5]

aspartate transaminase; K00813 aspartate aminotransferase [EC:2.6.1.1] [KO:K00813] [EC:2.6.1.1]

2-dehydro-3-deoxyphosphogluconate aldolase; K01625 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.16] [KO:K01625] [EC:4.1.3.16 4.1.2.14]

2-dehydro-3-deoxyphosphogluconate aldolase; K01625 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.16] [KO:K01625] [EC:4.1.3.16 4.1.2.14]

4-hydroxyproline epimerase; K12658 4-hydroxyproline epimerase [EC:5.1.1.8] [KO:K12658] [EC:5.1.1.8]

ornithine carbamoyltransferase; K00611 ornithine carbamoyltransferase [EC:2.1.3.3] [KO:K00611] [EC:2.1.3.3]

argininosuccinate synthase; K01940 argininosuccinate synthase [EC:6.3.4.5] [KO:K01940] [EC:6.3.4.5]

argininosuccinate lyase; K01755 argininosuccinate lyase [EC:4.3.2.1] [KO:K01755] [EC:4.3.2.1]

Arginase/agmatinase/formiminoglutamase; K01476 arginase [EC:3.5.3.1] [KO:K01476] [EC:3.5.3.1]

urea carboxylase; K01941 urea carboxylase [EC:6.3.4.6] [KO:K01941] [EC:6.3.4.6]

glutaminase; K01425 glutaminase [EC:3.5.1.2] [KO:K01425] [EC:3.5.1.2]

glutamine synthetase; K01915 glutamine synthetase [EC:6.3.1.2] [KO:K01915] [EC:6.3.1.2]

glutamate dehydrogenase (NAD(P)(+)); K00261 glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] [KO:K00261] [EC:1.4.1.3]

glutamate dehydrogenase (NADP(+)); K00262 glutamate dehydrogenase (NADP+) [EC:1.4.1.4] [KO:K00262] [EC:1.4.1.4]

amino-acid acetyltransferase; K14682 amino-acid N-acetyltransferase [EC:2.3.1.1] [KO:K14682] [EC:2.3.1.1]

acetylglutamate kinase; K00930 acetylglutamate kinase [EC:2.7.2.8] [KO:K00930] [EC:2.7.2.8]

N-acetyl-gamma-glutamyl-phosphate reductase; K00145 N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] [KO:K00145] [EC:1.2.1.38]

acetylornithine/succinyldiaminopimelate aminotransferase; K00821 acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] [KO:K00821] [EC:2.6.1.17 2.6.1.11]

acetylornithine deacetylase; K01438 acetylornithine deacetylase [EC:3.5.1.16] [KO:K01438] [EC:3.5.1.16]

CO2

Peptide

Ammonia

S-Adenosyl-L-methionine

Pyruvate

L-Glutamate

Glyoxylate

L-Aspartate

L-Arginine

L-Glutamine

L-Ornithine

Urea

Fumarate

Putrescine

L-Proline

Carbamoyl phosphate

Agmatine

Sarcosine

p-Coumaroyl-CoA

Creatine

Spermidine

L-Citrulline

4-Aminobutanoate

Feruloyl-CoA

5-Aminopentanoate

2,5-Dioxopentanoate

N-Carbamoylputrescine

N-Acetylornithine

L-Aspartate 4-semialdehyde

Nitric oxide

4-Aminobutyraldehyde

Guanidinoacetate

N-Acetyl-L-glutamate

Spermine

D-Proline

Creatinine

Homocarnosine

1,3-Diaminopropane

Urea-1-carboxylate

4-Guanidinobutanoate

N-Carbamoylsarcosine

5-Amino-2-oxopentanoic acid

S-Adenosylmethioninamine

Hydroxyproline

L-Glutamate 5-semialdehyde

N-Acetyl-L-glutamate 5-semialdehyde

Nopaline

4-Oxoproline

Phosphocreatine

N-Methylhydantoin

4-Guanidinobutanal

N-Acetylputrescine

4-Acetamidobutanoate

4-Guanidinobutanamide

Phosphoguanidinoacetate

L-Glutamyl 5-phosphate

N2-Succinyl-L-arginine

Norspermidine

N-(L-Arginino)succinate

N2-Succinyl-L-ornithine

cis-4-Hydroxy-D-proline

1-Pyrroline-2-carboxylate

5-Guanidino-2-oxopentanoate

(S)-1-Pyrroline-5-carboxylate

N-Acetyl-L-glutamate 5-phosphate

D-Octopine

L-1-Pyrroline-3-hydroxy-5-carboxylate

1-Pyrroline-4-hydroxy-2-carboxylate

p-Coumaroylagmatine

N-Succinyl-L-glutamate

N-Succinyl-L-glutamate 5-semialdehyde

N-(omega)-Hydroxyarginine

N4-Acetylaminobutanal

L-4-Hydroxyglutamate semialdehyde

Linatine

2-Oxo-4-hydroxy-5-aminovalerate

Pyrrole-2-carboxylate

L-Arginine phosphate

D-4-Hydroxy-2-oxoglutarate

L-erythro-4-Hydroxyglutamate

Feruloylputrescine

N-Acetyl-L-citrulline

gamma-L-Glutamylputrescine

gamma-Glutamyl-gamma-aminobutyraldehyde

4-(L-gamma-Glutamylamino)butanoate

N-Succinyl-L-citrulline

Carboxyspermidine

Carboxynorspermidine

Feruloylagmatine

p-Coumaroylputrescine