KEGG   PATHWAY: svi00623Help
Entry
svi00623                    Pathway                                
Name
Toluene degradation - Saccharomonospora viridis
Class
Metabolism; Xenobiotics biodegradation and metabolism
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Pathway map
Toluene degradation
svi00623

All organismsOrtholog table
Module
Toluene degradation, anaerobic, toluene => benzoyl-CoA [PATH:svi00623]
Toluene degradation, toluene => benzoate [PATH:svi00623]
Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH:svi00623]
Other DBs
BSID: 
GO: 
UMBBD: 
Organism
Saccharomonospora viridis [GN:svi]
Gene
sdhA; succinate dehydrogenase flavoprotein subunit [KO:K00239] [EC:1.3.99.1]
sdhA; succinate dehydrogenase flavoprotein subunit [KO:K00239] [EC:1.3.99.1]
succinate dehydrogenase subunit B; K00240 succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1] [KO:K00240] [EC:1.3.99.1]
fumarate reductase iron-sulfur subunit; K00240 succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1] [KO:K00240] [EC:1.3.99.1]
succinate dehydrogenase subunit C; K00241 succinate dehydrogenase cytochrome b556 subunit [KO:K00241]
succinate dehydrogenase subunit D; K00242 succinate dehydrogenase membrane anchor subunit [KO:K00242]
phenylpropionate dioxygenase ferredoxin subunit; K05710 dioxygenase ferredoxin subunit [KO:K05710]
Zn-dependent alcohol dehydrogenase; K00055 aryl-alcohol dehydrogenase [EC:1.1.1.90] [KO:K00055] [EC:1.1.1.90]
benzaldehyde dehydrogenase (NAD+); K00141 benzaldehyde dehydrogenase (NAD) [EC:1.2.1.28] [KO:K00141] [EC:1.2.1.28]
catechol 1; K03381 catechol 1,2-dioxygenase [EC:1.13.11.1] [KO:K03381] [EC:1.13.11.1]
dienelactone hydrolase-like enzyme; K01061 carboxymethylenebutenolidase [EC:3.1.1.45] [KO:K01061] [EC:3.1.1.45]
dienelactone hydrolase-like enzyme; K01061 carboxymethylenebutenolidase [EC:3.1.1.45] [KO:K01061] [EC:3.1.1.45]
Compound
C00042  
Succinate
C00091  
Succinyl-CoA
C00122  
Fumarate
C00156  
4-Hydroxybenzoate
C00180  
Benzoate
C00230  
3,4-Dihydroxybenzoate
C00261  
Benzaldehyde
C00512  
S-Benzoate coenzyme A
C00556  
Benzyl alcohol
C00587  
3-Hydroxybenzoate
C00633  
4-Hydroxybenzaldehyde
C01455  
Toluene
C01467  
3-Cresol
C01468  
4-Cresol
C01542  
o-Cresol
C02236  
4-Sulfobenzoate
C02923  
2,3-Dihydroxytoluene
C03067  
3-Hydroxybenzaldehyde
C03351  
3-Hydroxybenzyl alcohol
C04112  
3-Methyl-cis,cis-hexadienedioate
C04558  
3-Methylmuconolactone
C04559  
4-Methylmuconolactone
C04592  
Toluene-cis-dihydrodiol
C06677  
Toluene-4-sulfonate
C06678  
4-Sulfobenzyl alcohol
C06679  
4-Sulfobenzaldehyde
C06730  
4-Methylcatechol
C09816  
Benzylsuccinate
C09817  
Benzylsuccinyl-CoA
C09818  
E-Phenylitaconyl-CoA
C09819  
(Hydroxymethylphenyl)succinyl-CoA
C09820  
Benzoylsuccinyl-CoA
C18300  
2,4-Dichlorotoluene
C18301  
4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene
C18302  
4,6-Dichloro-3-methylcatechol
C18303  
3,5-Dichloro-2-methylmuconate
C18304  
2-Chloro-5-methyl-cis-dienelactone
C18305  
2-Chloro-5-methylmaleylacetate
C18306  
5-Methylmaleylacetate
C18307  
2-Methyl-3-oxoadipate
C18308  
3,5-Dichloro-2-methylmuconolactone
C18309  
3-Chloro-2-methyldienelactone
C18310  
3-Chloro-2-methylmaleylacetate
C18311  
4-Methyl-3-oxoadipate-enol-lactone
C18312  
4-Methyl-3-oxoadipate
Reference
  Authors
Vardar G, Wood TK
  Title
Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for synthesizing 4-methylresorcinol, methylhydroquinone, and pyrogallol.
  Journal
Appl Environ Microbiol 70:3253-62 (2004)
Reference
  Authors
Leuthner B, Heider J
  Title
Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate.
  Journal
J Bacteriol 182:272-7 (2000)
Reference
  Authors
Leutwein C, Heider J
  Title
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria.
  Journal
J Bacteriol 183:4288-95 (2001)
Reference
  Authors
Kuhner S, Wohlbrand L, Fritz I, Wruck W, Hultschig C, Hufnagel P, Kube M, Reinhardt R, Rabus R
  Title
Substrate-dependent regulation of anaerobic degradation pathways for toluene and  ethylbenzene in a denitrifying bacterium, strain EbN1.
  Journal
J Bacteriol 187:1493-503 (2005)
Reference
PMID:2050632
  Authors
Locher HH, Leisinger T, Cook AM
  Title
4-Toluene sulfonate methyl-monooxygenase from Comamonas testosteroni T-2: purification and some properties of the oxygenase component.
  Journal
J Bacteriol 173:3741-8 (1991)
Reference
PMID:8828208
  Authors
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM
  Title
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.
  Journal
Microbiology 142 ( Pt 9):2419-27 (1996)
Reference
  Authors
Mampel J, Ruff J, Junker F, Cook AM.
  Title
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.
  Journal
Microbiology 145 ( Pt 11):3255-64 (1999)
Reference
PMID:9006050
  Authors
Junker F, Kiewitz R, Cook AM
  Title
Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2.
  Journal
J Bacteriol 179:919-27 (1997)
KO pathway
 
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