KEGG   PATHWAY: swp00280
Entry
swp00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Shewanella piezotolerans
Class
Metabolism; Amino acid metabolism
Pathway map
swp00280  Valine, leucine and isoleucine degradation
swp00280

Module
swp_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:swp00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Shewanella piezotolerans [GN:swp]
Gene
swp_0361  Branched-chain amino acid amiotransferase [KO:K00826] [EC:2.6.1.42]
swp_0335  Branched-chain amino acid aminotransferase II [KO:K00826] [EC:2.6.1.42]
swp_1857  Glu/Leu/Phe/Val dehydrogenase, C terminal:Glu/Leu/Phe/Val dehydrogenase, dimerisation region [KO:K00263] [EC:1.4.1.9]
swp_2606  3-methyl-2-oxobutanoate dehydrogenase (lipoamide) [KO:K00166] [EC:1.2.4.4]
swp_2605  Transketolase, central region:Transketolase, C terminal [KO:K00167] [EC:1.2.4.4]
swp_2604  Biotin/lipoyl attachment:Catalytic domain of components of various dehydrogenase complexes:E3 binding [KO:K09699] [EC:2.3.1.168]
swp_4749  Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
swp_3442  Isovaleryl-CoA dehydrogenase [KO:K00253] [EC:1.3.8.4]
swp_0035  Enoyl-CoA hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase:3-hydroxyacyl-CoA dehydrogenase, NAD-binding [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
swp_3139  Enoyl-CoA hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase:3-hydroxyacyl-CoA dehydrogenase, NAD-binding [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
swp_3140  Thiolase [KO:K00632] [EC:2.3.1.16]
swp_0034  Thiolase [KO:K00632] [EC:2.3.1.16]
swp_3382  3-hydroxyisobutyrate dehydrogenase [KO:K00020] [EC:1.1.1.31]
swp_4179  Methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
swp_3386  Methylmalonate-semialdehyde dehydrogenase [KO:K00140] [EC:1.2.1.18 1.2.1.27]
swp_4178  Aminotransferase, class III [KO:K00822] [EC:2.6.1.18]
swp_0970  4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
swp_3445  Biotin/lipoyl attachment:Carbamoyl-phosphate synthase L chain, ATP-binding:Carbamoyl-phosphate synthetase large chain [KO:K01968] [EC:6.4.1.4]
swp_3443  Propionyl-CoA carboxylase [KO:K01969] [EC:6.4.1.4]
swp_3444  Enoyl-CoA hydratase/isomerase [KO:K13766] [EC:4.2.1.18]
swp_3448  HMG-CoA lyase-like protein [KO:K01640] [EC:4.1.3.4]
swp_3449  3-oxoacid CoA-transferase [KO:K01028] [EC:2.8.3.5]
swp_3450  3-oxoacid CoA-transferase [KO:K01029] [EC:2.8.3.5]
swp_3387  Thiolase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
swp00020  Citrate cycle (TCA cycle)
swp00240  Pyrimidine metabolism
swp00290  Valine, leucine and isoleucine biosynthesis
swp00640  Propanoate metabolism
swp00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG GENES (24)   
All databases (25)   

Download RDF
DBGET integrated database retrieval system