KEGG   PATHWAY: tpz00633Help
Entry
tpz00633                    Pathway                                
Name
Nitrotoluene degradation - Thermacetogenium phaeum
Class
Metabolism; Xenobiotics biodegradation and metabolism
BRITE hierarchy
Pathway map
Nitrotoluene degradation
tpz00633

All organismsOrtholog table
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BSID: 
UMBBD: 
GO: 
Organism
Thermacetogenium phaeum [GN:tpz]
Gene
periplasmic [NiFeSe] hydrogenase large subunit; K06281 hydrogenase large subunit [EC:1.12.99.6] [KO:K06281] [EC:1.12.99.6]
periplasmic [NiFeSe] hydrogenase small subunit; K06282 hydrogenase small subunit [EC:1.12.99.6] [KO:K06282] [EC:1.12.99.6]
cooS; carbon monoxide dehydrogenase catalytic subunit CooS [KO:K00198] [EC:1.2.7.4 1.2.99.2]
cooS1; carbon monoxide dehydrogenase 1 [KO:K00198] [EC:1.2.7.4 1.2.99.2]
acsB; carbon monoxide dehydrogenase/acetyl-CoA synthase subunit beta [KO:K00198] [EC:1.2.7.4 1.2.99.2]
ygfS; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein YgfS [KO:K00196]
Compound
C01468  
4-Cresol
C06002  
(S)-Methylmalonate semialdehyde
C11006  
2,4-Dinitrotoluene
C14401  
2,4-Diaminotoluene
C16391  
Trinitrotoluene
C16392  
4-Hydroxylamino-2,6-dinitrotoluene
C16393  
2-Hydroxylamino-4,6-dinitrotoluene
C16394  
4-Amino-2,6-dinitrotoluene
C16395  
2-Amino-4,6-dinitrotoluene
C16396  
2,4-Diamino-6-nitrotoluene
C16397  
2,6-Diamino-4-nitrotoluene
C16398  
2-Amino-4-nitrotoluene
C16399  
2,4-Diamino-6-hydroxylaminotoluene
C16400  
2,4,6-Triaminotoluene
C16401  
2,4,6-Trihydroxytoluene
C16402  
2,4-Dihydroxylamino-6-nitrotoluene
C16403  
4-Amino-2-hydroxylamino-6-nitrotoluene
C16411  
4,4',6,6'-Tetranitro-2,2'-azoxytoluene
C16412  
2,4',6,6'-Tetranitro-2',4-azoxytoluene
C16413  
2,2',6,6'-Tetranitro-4,4'-azoxytoluene
C16414  
2-Amino-5-hydroxyl-4-hydroxylamino-6-nitrotoluene
C16420  
4-Acetamido-2-amino-6-nitrotoluene
C18315  
4-Methyl-5-nitrocatechol
C18316  
2-Hydroxy-5-methylquinone
C18317  
2,4,5-Trihydroxytoluene
C18318  
cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate
C18320  
4-Amino-2-nitrotoluene
Reference
  Authors
Esteve-Nunez A, Ramos JL.
  Title
Metabolism of 2,4,6-Trinitrotoluene by Pseudomonas sp. JLR11.
  Journal
Environmental science & technology 32:3802-3808 (1998)
Reference
PMID:8534088
  Authors
Gilcrease PC, Murphy VG.
  Title
Bioconversion of 2,4-diamino-6-nitrotoluene to a novel metabolite under anoxic and aerobic conditions.
  Journal
Appl Environ Microbiol 61:4209-14 (1995)
Reference
  Authors
Esteve-Nunez A, Caballero A, Ramos JL.
  Title
Biological degradation of 2,4,6-trinitrotoluene.
  Journal
Microbiol Mol Biol Rev 65:335-52, table of contents (2001)
Reference
  Authors
Fleischmann TJ, Walker KC, Spain JC, Hughes JB, Morrie Craig A.
  Title
Anaerobic transformation of 2,4,6-TNT by bovine ruminal microbes.
  Journal
Biochem Biophys Res Commun 314:957-63 (2004)
Reference
  Authors
Borch T, Gerlach R.
  Title
Use of reversed-phase high-performance liquid chromatography-diode array detection for complete separation of 2,4,6-trinitrotoluene metabolites and EPA Method 8330 explosives: influence of temperature and an ion-pair reagent.
  Journal
J Chromatogr A 1022:83-94 (2004)
Reference
  Authors
Yin H, Wood TK, Smets BF.
  Title
Reductive transformation of TNT by Escherichia coli: pathway description.
  Journal
Appl Microbiol Biotechnol 67:397-404 (2005)
Reference
  Authors
Kutty R, Bennett GN.
  Title
Biochemical characterization of trinitrotoluene transforming oxygen-insensitive nitroreductases from Clostridium acetobutylicum ATCC 824.
  Journal
Arch Microbiol 184:158-67 (2005)
Reference
  Authors
Fiorella PD, Spain JC.
  Title
Transformation of 2,4,6-Trinitrotoluene by Pseudomonas pseudoalcaligenes JS52.
  Journal
Appl Environ Microbiol 63:2007-2015 (1997)
Reference
  Authors
Gonzalez-Perez MM, van Dillewijn P, Wittich RM, Ramos JL.
  Title
Escherichia coli has multiple enzymes that attack TNT and release nitrogen for growth.
  Journal
Environ Microbiol 9:1535-40 (2007)
Reference
  Authors
Noguera DR, Freedman DL
  Title
Reduction and Acetylation of 2,4-Dinitrotoluene by a Pseudomonas aeruginosa Strain.
  Journal
Appl Environ Microbiol 62:2257-63 (1996)
Reference
PMID:9922262
  Authors
Haigler BE, Johnson GR, Suen WC, Spain JC
  Title
Biochemical and genetic evidence for meta-ring cleavage of 2,4, 5-trihydroxytoluene in Burkholderia sp. strain DNT.
  Journal
J Bacteriol 181:965-72 (1999)
Reference
  Authors
Johnson GR, Jain RK, Spain JC
  Title
Origins of the 2,4-dinitrotoluene pathway.
  Journal
J Bacteriol 184:4219-32 (2002)
KO pathway
 
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