KEGG PATHWAY: tth00230

PATHWAY: tth00230

Entry

tth00230 Pathway

Name

Purine metabolism - Thermus thermophilus HB27

Class

Metabolism; Nucleotide metabolism

Pathway map

tth00230

Purine metabolism

Module

tth_M00005	PRPP biosynthesis, ribose 5P => PRPP [PATH:tth00230]
tth_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:tth00230]
tth_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tth00230]
tth_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:tth00230]
tth_M00546	Purine degradation, xanthine => urea [PATH:tth00230]

Other DBs

BSID:

16580

GO:

0042278

Organism

Thermus thermophilus HB27 [GN:tth]

Gene

TTC0160	ADP-ribose pyrophosphatase; K01515 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K01515] [EC:3.6.1.13]
TTC0511	mutT; phosphohydrolase (mutT/nudix family protein) [KO:K01515] [EC:3.6.1.13]
TTC1659	phosphopentomutase; K01839 phosphopentomutase [EC:5.4.2.7] [KO:K01839] [EC:5.4.2.7]
TTC1630	phosphoglucomutase; K01835 phosphoglucomutase [EC:5.4.2.2] [KO:K01835] [EC:5.4.2.2]
TTC1184	ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] [KO:K00948] [EC:2.7.6.1]
TTC1274	ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] [KO:K00948] [EC:2.7.6.1]
TTC1156	amidophosphoribosyltransferase; K00764 amidophosphoribosyltransferase [EC:2.4.2.14] [KO:K00764] [EC:2.4.2.14]
TTC0460	phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase [EC:6.3.4.13] [KO:K01945] [EC:6.3.4.13]
TTC0459	phosphoribosylglycinamide formyltransferase; K11175 phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] [KO:K11175] [EC:2.1.2.2]
TTC1153	phosphoribosylformylglycinamidine synthase I; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
TTC1155	phosphoribosylformylglycinamidine synthase II; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
TTC1152	cytoplasmic protein; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
TTC1619	phosphoribosylaminoimidazole synthetase; K01933 phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] [KO:K01933] [EC:6.3.3.1]
TTC0137	phosphoribosylaminoimidazole carboxylase ATPase subunit; K01589 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] [KO:K01589] [EC:6.3.4.18]
TTC0138	phosphoribosylaminoimidazole carboxylase catalytic subunit; K01588 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] [KO:K01588] [EC:5.4.99.18]
TTC1151	phosphoribosylamidoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] [KO:K01923] [EC:6.3.2.6]
TTC1149	adenylosuccinate lyase; K01756 adenylosuccinate lyase [EC:4.3.2.2] [KO:K01756] [EC:4.3.2.2]
TTC0561	purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
TTC1249	adenine phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] [KO:K00759] [EC:2.4.2.7]
TTC1250	adenine phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] [KO:K00759] [EC:2.4.2.7]
TTC0964	5'-nucleotidase; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
TTC1625	surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5]
TT_P0028	surE; survival protein surE [KO:K03787] [EC:3.1.3.5]
TTC0194	purine nucleoside phosphorylase; K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] [KO:K03783] [EC:2.4.2.1]
TTC1070	purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase [EC:2.4.2.1] [KO:K03784] [EC:2.4.2.1]
TTC1766	hypoxanthine-guanine phosphoribosyltransferase; K00760 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] [KO:K00760] [EC:2.4.2.8]
TTC0064	inosine-5'-monophosphate dehydrogenase; K00088 IMP dehydrogenase [EC:1.1.1.205] [KO:K00088] [EC:1.1.1.205]
TTC1798	ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
TTC1583	mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K02428] [EC:3.6.1.19]
TTC1290	deoxyribonucleotide triphosphate pyrophosphatase; K02428 dITP/XTP pyrophosphatase [EC:3.6.1.19] [KO:K02428] [EC:3.6.1.19]
TTC1859	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); K01518 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] [KO:K01518] [EC:3.6.1.17]
TTC1519	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); K01518 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] [KO:K01518] [EC:3.6.1.17]
TTC1187	guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
TTC1197	gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
TTC1611	pyruvate kinase; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
TT_P0162	ribonucleotide-diphosphate reductase subunit alpha; K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] [KO:K00525] [EC:1.17.4.1]
TTC1930	ribonucleoside-diphosphate reductase alpha chain; K00525 ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] [KO:K00525] [EC:1.17.4.1]
TT_P0161	ribonucleoside-diphosphate reductase beta chain; K00526 ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] [KO:K00526] [EC:1.17.4.1]
TTC0044	dNTP triphosphohydrolase; K01129 dGTPase [EC:3.1.5.1] [KO:K01129] [EC:3.1.5.1]
TTC1300	DNA-directed RNA polymerase subunit alpha; K03040 DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] [KO:K03040] [EC:2.7.7.6]
TTC1461	rpoB; DNA-directed RNA polymerase subunit beta [KO:K03043] [EC:2.7.7.6]
TTC1460	DNA-directed RNA polymerase beta' chain; K03046 DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] [KO:K03046] [EC:2.7.7.6]
TTC1196	rpoZ; DNA-directed RNA polymerase subunit omega [KO:K03060] [EC:2.7.7.6]
TTC0690	DNA polymerase I; K02335 DNA polymerase I [EC:2.7.7.7] [KO:K02335] [EC:2.7.7.7]
TTC1806	DNA polymerase III alpha subunit; K02337 DNA polymerase III subunit alpha [EC:2.7.7.7] [KO:K02337] [EC:2.7.7.7]
TTC1609	DNA polymerase III; K02338 DNA polymerase III subunit beta [EC:2.7.7.7] [KO:K02338] [EC:2.7.7.7]
TTC1509	DNA polymerase III subunit; K02343 DNA polymerase III subunit gamma/tau [EC:2.7.7.7] [KO:K02343] [EC:2.7.7.7]
TTC1588	DNA polymerase III holoenzyme tau subunit; K02343 DNA polymerase III subunit gamma/tau [EC:2.7.7.7] [KO:K02343] [EC:2.7.7.7]
TTC0434	cytoplasmic protein; K02340 DNA polymerase III subunit delta [EC:2.7.7.7] [KO:K02340] [EC:2.7.7.7]
TTC0206	hypothetical protein; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
TTC1355	guanosine-3'; K01139 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2] [KO:K01139] [EC:3.1.7.2]
TTC0636	exopolyphosphatase; K01524 exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] [KO:K01524] [EC:3.6.1.40 3.6.1.11]
TTC1764	adenylosuccinate synthetase; K01939 adenylosuccinate synthase [EC:6.3.4.4] [KO:K01939] [EC:6.3.4.4]
TTC1307	adenylate kinase; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
TTC0774	polynucleotide phosphorylase; K00962 polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] [KO:K00962] [EC:2.7.7.8]
TTC0307	sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]

Compound

C00002	ATP
C00008	ADP
C00011	CO2
C00014	NH3
C00020	AMP
C00035	GDP
C00037	Glycine
C00039	DNA
C00044	GTP
C00046	RNA
C00048	Glyoxylate
C00053	3'-Phosphoadenylyl sulfate
C00054	Adenosine 3',5'-bisphosphate
C00059	Sulfate
C00064	L-Glutamine
C00081	ITP
C00086	Urea
C00104	IDP
C00117	D-Ribose 5-phosphate
C00119	5-Phospho-alpha-D-ribose 1-diphosphate
C00130	IMP
C00131	dATP
C00144	GMP
C00147	Adenine
C00169	Carbamoyl phosphate
C00206	dADP
C00212	Adenosine
C00224	Adenylyl sulfate
C00242	Guanine
C00262	Hypoxanthine
C00286	dGTP
C00294	Inosine
C00301	ADP-ribose
C00330	Deoxyguanosine
C00360	dAMP
C00361	dGDP
C00362	dGMP
C00366	Urate
C00385	Xanthine
C00387	Guanosine
C00499	Allantoate
C00559	Deoxyadenosine
C00575	3',5'-Cyclic AMP
C00603	(-)-Ureidoglycolate
C00620	alpha-D-Ribose 1-phosphate
C00655	Xanthosine 5'-phosphate
C00700	XTP
C00802	Oxalureate
C00942	3',5'-Cyclic GMP
C01228	Guanosine 3',5'-bis(diphosphate)
C01260	P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261	P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344	dIDP
C01345	dITP
C01367	3'-AMP
C01762	Xanthosine
C02091	(S)-Ureidoglycine
C02348	(R)(-)-Allantoin
C02350	(S)(+)-Allantoin
C02353	2',3'-Cyclic AMP
C02718	N-Formiminoglycine
C03090	5-Phosphoribosylamine
C03373	Aminoimidazole ribotide
C03483	Adenosine tetraphosphate
C03614	Inosine 5'-tetraphosphate
C03794	N6-(1,2-Dicarboxyethyl)-AMP
C03838	5'-Phosphoribosylglycinamide
C04051	5-Amino-4-imidazolecarboxyamide
C04376	5'-Phosphoribosyl-N-formylglycinamide
C04392	P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494	Guanosine 3'-diphosphate 5'-triphosphate
C04640	2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677	1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734	1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751	1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823	1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239	5-Aminoimidazole
C05512	Deoxyinosine
C05513	Urate-3-ribonucleoside
C05515	5-Ureido-4-imidazole carboxylate
C05516	5-Amino-4-imidazole carboxylate
C05993	Acetyl adenylate
C06193	Guanosine 3'-phosphate
C06194	2',3'-Cyclic GMP
C06195	Imidazolone
C06196	2'-Deoxyinosine 5'-phosphate
C06197	P1,P3-Bis(5'-adenosyl) triphosphate
C06433	5'-Benzoylphosphoadenosine
C06435	5'-Butyrylphosphoinosine
C11821	5-Hydroxyisourate
C12248	5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667	5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole

Reference

PMID:10601204

Authors

Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.

Title

Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.

Journal

J Bacteriol 181:7479-84 (1999)

Reference

PMID:10986234

Authors

Xi H, Schneider BL, Reitzer L.

Title

Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.

Journal

J Bacteriol 182:5332-41 (2000)

KO pathway

ko00230

All links

Pathway (5)   
   KEGG MODULE (4)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (56)   
   KEGG GENES (56)   
All databases (62)   

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