KEGG PATHWAY: vcm00240

PATHWAY: vcm00240

Entry

vcm00240 Pathway

Name

Pyrimidine metabolism - Vibrio cholerae M66-2

Class

Metabolism; Nucleotide metabolism

Pathway map

vcm00240

Pyrimidine metabolism

Module

vcm_M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:vcm00240]
vcm_M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH:vcm00240]
vcm_M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:vcm00240]
vcm_M00053	Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH:vcm00240]

Other DBs

BSID:

96040

GO:

0006220

Organism

Vibrio cholerae M66-2 [GN:vcm]

Gene

VCM66_2312	carB; carbamoyl phosphate synthase large subunit [KO:K01955] [EC:6.3.5.5]
VCM66_2313	carA; carbamoyl phosphate synthase small subunit [KO:K01956] [EC:6.3.5.5]
VCM66_2432	pyrB; aspartate carbamoyltransferase catalytic subunit [KO:K00609] [EC:2.1.3.2]
VCM66_2433	pyrI; aspartate carbamoyltransferase regulatory subunit [KO:K00610]
VCM66_A0885	pyrC; dihydroorotase [KO:K01465] [EC:3.5.2.3]
VCM66_1434	pyrD; dihydroorotate dehydrogenase 2 [KO:K00226] [EC:1.3.98.1]
VCM66_0199	pyrE; orotate phosphoribosyltransferase [KO:K00762] [EC:2.4.2.10]
VCM66_1835	pyrF; orotidine 5'-phosphate decarboxylase [KO:K01591] [EC:4.1.1.23]
VCM66_1840	cmk; cytidylate kinase [KO:K00945] [EC:2.7.4.14]
VCM66_2181	pyrH; uridylate kinase [KO:K09903] [EC:2.7.4.22]
VCM66_0714	ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
VCM66_0605	pnp; polynucleotide phosphorylase/polyadenylase [KO:K00962] [EC:2.7.7.8]
VCM66_0441	putative deoxyribonucleotide triphosphate pyrophosphatase; K02428 dITP/XTP pyrophosphatase [EC:3.6.1.19] [KO:K02428] [EC:3.6.1.19]
VCM66_2371	pyrG; CTP synthetase [KO:K01937] [EC:6.3.4.2]
VCM66_2491	rpoA; DNA-directed RNA polymerase subunit alpha [KO:K03040] [EC:2.7.7.6]
VCM66_0312	rpoB; DNA-directed RNA polymerase subunit beta [KO:K03043] [EC:2.7.7.6]
VCM66_0313	rpoC; DNA-directed RNA polymerase subunit beta' [KO:K03046] [EC:2.7.7.6]
VCM66_2629	rpoZ; DNA-directed RNA polymerase subunit omega [KO:K03060] [EC:2.7.7.6]
VCM66_0108	polI; DNA polymerase I [KO:K02335] [EC:2.7.7.7]
VCM66_2168	dnaE; DNA polymerase III subunit alpha [KO:K02337] [EC:2.7.7.7]
VCM66_0013	dnaN; DNA polymerase III subunit beta [KO:K02338] [EC:2.7.7.7]
VCM66_1009	dnaZX; DNA polymerase III subunits gamma and tau [KO:K02343] [EC:2.7.7.7]
VCM66_0909	holA; DNA polymerase III subunit delta [KO:K02340] [EC:2.7.7.7]
VCM66_1939	holB; DNA polymerase III subunit delta' [KO:K02341] [EC:2.7.7.7]
VCM66_0284	DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
VCM66_1245	DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon [EC:2.7.7.7] [KO:K02342] [EC:2.7.7.7]
VCM66_2156	dnaQ; DNA polymerase III subunit epsilon [KO:K02342] [EC:2.7.7.7]
VCM66_2424	holC; DNA polymerase III subunit chi [KO:K02339] [EC:2.7.7.7]
VCM66_0614	holD; DNA polymerase III subunit psi [KO:K02344] [EC:2.7.7.7]
VCM66_0993	udk; uridine kinase [KO:K00876] [EC:2.7.1.48]
VCM66_A0504	putative 5'-nucleotidase; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
VCM66_2097	ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.6.1.45 3.1.3.5]
VCM66_0489	surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5]
VCM66_1902	hypothetical protein; K08722 5'-nucleotidase [EC:3.1.3.5] [KO:K08722] [EC:3.1.3.5]
VCM66_A0132	udp-2; uridine phosphorylase [KO:K00757] [EC:2.4.2.3]
VCM66_0989	udp-1; uridine phosphorylase [KO:K00757] [EC:2.4.2.3]
VCM66_2148	upp; uracil phosphoribosyltransferase [KO:K00761] [EC:2.4.2.9]
VCM66_2373	mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.8]
VCM66_1137	trxB; thioredoxin reductase [KO:K00384] [EC:1.8.1.9]
VCM66_A0470	nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K00527] [EC:1.17.4.2]
VCM66_1211	nrdA; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
VCM66_1210	nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
VCM66_0633	thyA; thymidylate synthase [KO:K00560] [EC:2.1.1.45]
VCM66_1186	cdd; cytidine deaminase [KO:K01489] [EC:3.5.4.5]
VCM66_2272	deoA; thymidine phosphorylase [KO:K00758] [EC:2.4.2.4]
VCM66_A0050	deoD-2; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
VCM66_2270	deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
VCM66_A0799	putative deoxycytidylate deaminase; K01493 dCMP deaminase [EC:3.5.4.12] [KO:K01493] [EC:3.5.4.12]
VCM66_1122	tdk; thymidine kinase [KO:K00857] [EC:2.7.1.21]
VCM66_1940	tmk; thymidylate kinase [KO:K00943] [EC:2.7.4.9]
VCM66_2482	cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein [KO:K01119] [EC:3.1.4.16]
VCM66_2339	putative 2; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16] [KO:K01119] [EC:3.1.4.16]

Compound

C00015	UDP
C00029	UDP-glucose
C00039	DNA
C00046	RNA
C00055	CMP
C00063	CTP
C00064	L-Glutamine
C00075	UTP
C00086	Urea
C00099	beta-Alanine
C00105	UMP
C00106	Uracil
C00112	CDP
C00119	5-Phospho-alpha-D-ribose 1-diphosphate
C00169	Carbamoyl phosphate
C00178	Thymine
C00214	Thymidine
C00222	3-Oxopropanoate
C00239	dCMP
C00295	Orotate
C00299	Uridine
C00337	(S)-Dihydroorotate
C00342	Thioredoxin
C00343	Thioredoxin disulfide
C00363	dTDP
C00364	dTMP
C00365	dUMP
C00380	Cytosine
C00383	Malonate
C00429	5,6-Dihydrouracil
C00438	N-Carbamoyl-L-aspartate
C00458	dCTP
C00459	dTTP
C00460	dUTP
C00475	Cytidine
C00526	Deoxyuridine
C00672	2-Deoxy-D-ribose 1-phosphate
C00705	dCDP
C00813	Barbiturate
C00881	Deoxycytidine
C00906	5,6-Dihydrothymine
C01013	3-Hydroxypropanoate
C01103	Orotidine 5'-phosphate
C01168	Pseudouridine 5'-phosphate
C01346	dUDP
C01368	3'-UMP
C01563	Carbamate
C02067	Pseudouridine
C02170	Methylmalonate
C02354	2',3'-Cyclic CMP
C02355	2',3'-Cyclic UMP
C02376	5-Methylcytosine
C02642	3-Ureidopropionate
C03997	5-Hydroxymethyldeoxycytidylate
C05100	3-Ureidoisobutyrate
C05145	3-Aminoisobutyric acid
C05281	5-Methylbarbiturate
C05822	3'-CMP
C06198	P1,P4-Bis(5'-uridyl) tetraphosphate
C11038	2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039	2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607	3-Oxo-3-ureidopropanoate
C20231	(Z)-3-Ureidoacrylate peracid
C20249	(Z)-3-Peroxyaminoacrylate
C20253	Aminoacrylate
C20254	Ureidoacrylate

KO pathway

ko00240

All links

Pathway (3)   
   KEGG MODULE (2)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (52)   
   KEGG GENES (52)   
All databases (56)   

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