KEGG PATHWAY: vcm00362

PATHWAY: vcm00362

Entry

vcm00362 Pathway

Name

Benzoate degradation - Vibrio cholerae M66-2

Class

Metabolism; Xenobiotics biodegradation and metabolism

Pathway map

vcm00362

Benzoate degradation

Module

vcm_M00540	Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA [PATH:vcm00362]
vcm_M00541	Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA [PATH:vcm00362]
vcm_M00547	Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH:vcm00362]
vcm_M00548	Benzene degradation, benzene => catechol [PATH:vcm00362]
vcm_M00551	Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:vcm00362]
vcm_M00568	Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:vcm00362]
vcm_M00569	Catechol meta-cleavage, catechol => pyruvate + acetaldehyde [PATH:vcm00362]

Other DBs

BSID:

154209

UMBBD:

benz2 benz abs

GO:

0043639

Organism

Vibrio cholerae M66-2 [GN:vcm]

Gene

VCM66_1001	fadI; 3-ketoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
VCM66_2679	fadA; 3-ketoacyl-CoA thiolase [KO:K00632] [EC:2.3.1.16]
VCM66_1957	adhE; bifunctional acetaldehyde-CoA/alcohol dehydrogenase [KO:K04072] [EC:1.1.1.1 1.2.1.10]
VCM66_A0648	acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] [KO:K00626] [EC:2.3.1.9]

Compound

C00022	Pyruvate
C00024	Acetyl-CoA
C00036	Oxaloacetate
C00084	Acetaldehyde
C00090	Catechol
C00091	Succinyl-CoA
C00146	Phenol
C00156	4-Hydroxybenzoate
C00180	Benzoate
C00196	2,3-Dihydroxybenzoate
C00230	3,4-Dihydroxybenzoate
C00332	Acetoacetyl-CoA
C00512	S-Benzoate coenzyme A
C00527	Glutaryl-CoA
C00530	Hydroquinone
C00587	3-Hydroxybenzoate
C00596	2-Hydroxy-2,4-pentadienoate
C00628	2,5-Dihydroxybenzoate
C00682	2-Hydroxymuconate semialdehyde
C00846	3-Oxoadipate
C00877	Crotonoyl-CoA
C01063	6-Carboxyhexanoyl-CoA
C01144	(S)-3-Hydroxybutanoyl-CoA
C01163	3-Carboxy-cis,cis-muconate
C01278	2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C01407	Benzene
C02222	2-Maleylacetate
C02232	3-Oxoadipyl-CoA
C02411	Glutaconyl-1-CoA
C02480	cis,cis-Muconate
C02501	2-Hydroxymuconate
C02519	4-Methoxybenzoate
C02814	Benzene-1,2,4-triol
C02949	4-Hydroxybenzoyl-CoA
C03453	gamma-Oxalocrotonate
C03586	2-Oxo-2,3-dihydrofuran-5-acetate
C03589	4-Hydroxy-2-oxopentanoate
C03671	2-Pyrone-4,6-dicarboxylate
C03676	3-Hydroxy-cis,cis-muconate
C04091	cis-1,2-Dihydrobenzene-1,2-diol
C04115	4-Carboxy-4-hydroxy-2-oxoadipate
C04324	(1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
C04434	(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
C04480	3-Carboxy-2-hydroxymuconate semialdehyde
C04484	4-Carboxy-2-hydroxymuconate semialdehyde
C04553	3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C05375	2-Hydroxy-2-hydropyrone-4,6-dicarboxylate
C06033	Parapyruvate
C06035	4-Methylene-2-oxoglutarate
C06321	(1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate
C06322	S-1,5-Cyclohexadiene-1-carboxylate coenzymeA
C06333	2-Aminobenzenesulfonate
C06336	3-Sulfocatechol
C06714	3-Hydroxypimeloyl-CoA
C06715	3-Oxopimeloyl-CoA
C06723	6-Carboxyhex-2-enoyl-CoA
C06749	6-Hydroxycyclohex-1-enecarbonyl-CoA
C09809	Cyclohex-2,5-diene-1-carboxyl-CoA
C09810	Cyclohex-1,4-diene-1-carboxyl-CoA
C09811	Cyclohex-1-ene-1-carboxyl-CoA
C09812	2-Hydroxycyclohexane-1-carboxyl-CoA
C09813	2-Ketocyclohexane-1-carboxyl-CoA
C09821	6-Ketoxycyclohex-1-ene-1-carboxyl-CoA
C09822	Cyclohexane-1-carboxylate
C09823	Cyclohexane-1-carboxyl-CoA
C14610	(S)-5-Oxo-2,5-dihydrofuran-2-acetate

Reference

PMID:19258534

Authors

Carmona M, Zamarro MT, Blazquez B, Durante-Rodriguez G, Juarez JF, Valderrama JA, Barragan MJ, Garcia JL, Diaz E

Title

Anaerobic catabolism of aromatic compounds: a genetic and genomic view.

Journal

Microbiol Mol Biol Rev 73:71-133 (2009)

Reference

PMID:12486039

Authors

Hara H, Masai E, Miyauchi K, Katayama Y, Fukuda M.

Title

Characterization of the 4-carboxy-4-hydroxy-2-oxoadipate aldolase gene and operon structure of the protocatechuate 4,5-cleavage pathway genes in Sphingomonas paucimobilis SYK-6.

Journal

J Bacteriol 185:41-50 (2003)

Reference

PMID:15277747

Authors

Maruyama K, Shibayama T, Ichikawa A, Sakou Y, Yamada S, Sugisaki H.

Title

Cloning and characterization of the genes encoding enzymes for the protocatechuate meta-degradation pathway of Pseudomonas ochraceae NGJ1.

Journal

Biosci Biotechnol Biochem 68:1434-41 (2004)

Reference

PMID:10589735

Authors

Mampel J, Ruff J, Junker F, Cook AM.

Title

The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.

Journal

Microbiology 145 ( Pt 11):3255-64 (1999)

Reference

PMID:8002948

Authors

Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM.

Title

Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid.

Journal

Biochem J 300 ( Pt 2):429-36 (1994)

Reference

PMID:8990279

Authors

Harwood CS, Gibson J.

Title

Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?

Journal

J Bacteriol 179:301-9 (1997)

Reference

PMID:17122342

Authors

Peters F, Shinoda Y, McInerney MJ, Boll M.

Title

Cyclohexa-1,5-diene-1-carbonyl-coenzyme A (CoA) hydratases of Geobacter metallireducens and Syntrophus aciditrophicus: Evidence for a common benzoyl-CoA degradation pathway in facultative and strict anaerobes.

Journal

J Bacteriol 189:1055-60 (2007)

Reference

PMID:11053377

Authors

Cowles CE, Nichols NN, Harwood CS.

Title

BenR, a XylS homologue, regulates three different pathways of aromatic acid degradation in Pseudomonas putida.

Journal

J Bacteriol 182:6339-46 (2000)

Reference

PMID:12514037

Authors

Smith MA, Weaver VB, Young DM, Ornston LN.

Title

Genes for chlorogenate and hydroxycinnamate catabolism (hca) are linked to functionally related genes in the dca-pca-qui-pob-hca chromosomal cluster of Acinetobacter sp. strain ADP1.

Journal

Appl Environ Microbiol 69:524-32 (2003)

Reference

PMID:18312395

Authors

Kuntze K, Shinoda Y, Moutakki H, McInerney MJ, Vogt C, Richnow HH, Boll M

Title

6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes.

Journal

Environ Microbiol 10:1547-56 (2008)

Reference

PMID:10781543

Authors

Pelletier DA, Harwood CS

Title

2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris.

Journal

J Bacteriol 182:2753-60 (2000)

Reference

PMID:11282627

Authors

Elshahed MS, Bhupathiraju VK, Wofford NQ, Nanny MA, McInerney MJ

Title

Metabolism of benzoate, cyclohex-1-ene carboxylate, and cyclohexane carboxylate by "Syntrophus aciditrophicus" strain SB in syntrophic association with H(2)-using microorganisms.

Journal

Appl Environ Microbiol 67:1728-38 (2001)

Reference

PMID:21219457

Authors

Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E

Title

Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.

Journal

Mol Microbiol 79:359-74 (2011)

KO pathway

ko00362

All links

Pathway (1)   
   BioSystems (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG GENES (4)   
All databases (6)   

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