KEGG   PATHWAY: xca00450Help
Entry
xca00450                    Pathway                                

Name
Selenocompound metabolism - Xanthomonas campestris pv. campestris B100
Class
Metabolism; Metabolism of other amino acids
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Pathway map
Selenocompound metabolism
xca00450

All organismsOrtholog table
Organism
Xanthomonas campestris pv. campestris B100 [GN:xca]
Gene
cystathionine gamma-synthase; K01739 cystathionine gamma-synthase [EC:2.5.1.48] [KO:K01739] [EC:2.5.1.48]
metH1; methionine synthase (N-terminal fragment) [KO:K00548] [EC:2.1.1.13]
metH2; methionine synthase (C-terminal fragment) [KO:K00548] [EC:2.1.1.13]
metE; 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase [KO:K00549] [EC:2.1.1.14]
Cys/Met metabolism PLP-dependent enzyme; K01758 cystathionine gamma-lyase [EC:4.4.1.1] [KO:K01758] [EC:4.4.1.1]
csd; cysteine desulfurase [KO:K11717] [EC:4.4.1.16 2.8.1.7]
thioredoxin-disulfide reductase; K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9] [KO:K00384] [EC:1.8.1.9]
thioredoxin reductase; K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9] [KO:K00384] [EC:1.8.1.9]
cysNC; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase [KO:K00955] [EC:2.7.1.25 2.7.7.4]
cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
metG; methionyl-tRNA synthetase [KO:K01874] [EC:6.1.1.10]
Compound
C00017  
Protein
C00041  
L-Alanine
C01528  
Hydrogen selenide
C02535  
Dimethyl selenide
C05172  
Selenophosphoric acid
C05335  
L-Selenomethionine
C05336  
Selenomethionyl-tRNA(Met)
C05684  
Selenite
C05686  
Adenylylselenate
C05688  
L-Selenocysteine
C05689  
Se-Methyl-L-selenocysteine
C05690  
Se-Methylselenomethionine
C05695  
gamma-Glutamyl-Se-methylselenocysteine
C05697  
Selenate
C05698  
Selenohomocysteine
C05699  
L-Selenocystathionine
C05703  
Methaneselenol
C06481  
L-Seryl-tRNA(Sec)
C06482  
L-Selenocysteinyl-tRNA(Sec)
C16638  
O-Phosphoseryl-tRNA(Sec)
C18870  
Selenodiglutathione
C18871  
Glutathioselenol
C18872  
Trimethylselenonium
C18893  
1-Methylseleno-N-acetyl-D-galactosamine
C18902  
Methylselenic acid
C18904  
Methylselenopyruvate
C18905  
Methylselenocysteine Se-oxide
Reference
  Authors
Hoefig CS, Renko K, Kohrle J, Birringer M, Schomburg L
  Title
Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture.
  Journal
J Nutr Biochem (2010)
Reference
  Authors
McKenzie MJ, Hunter DA, Pathirana R, Watson LM, Joyce NI, Matich AJ, Rowan DD, Brummell DA
  Title
Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators.
  Journal
Transgenic Res 18:407-24 (2009)
Reference
  Authors
Pinto JT, Lee JI, Sinha R, Macewan ME, Cooper AJ
  Title
Chemopreventive mechanisms of alpha-keto acid metabolites of naturally occurring  organoselenium compounds.
  Journal
Amino Acids (2010)
Reference
  Authors
Suzuki KT, Kurasaki K, Suzuki N
  Title
Selenocysteine beta-lyase and methylselenol demethylase in the metabolism of Se-methylated selenocompounds into selenide.
  Journal
Biochim Biophys Acta 1770:1053-61 (2007)
Reference
  Authors
Gromer S, Gross JH
  Title
Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium.
  Journal
J Biol Chem 277:9701-6 (2002)
KO pathway
 

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