KEGG   PATHWAY: xfm00290
Entry
xfm00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Xylella fastidiosa M12
Class
Metabolism; Amino acid metabolism
Pathway map
xfm00290  Valine, leucine and isoleucine biosynthesis
xfm00290

Module
xfm_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:xfm00290]
xfm_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:xfm00290]
xfm_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:xfm00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Xylella fastidiosa M12 [GN:xfm]
Gene
Xfasm12_1204  threonine dehydratase catabolic [KO:K01754] [EC:4.3.1.19]
Xfasm12_1542  3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Xfasm12_1541  3-isopropylmalate dehydratase [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Xfasm12_1539  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Xfasm12_1202  acetolactate synthase isozyme II large subunit [KO:K01652] [EC:2.2.1.6]
Xfasm12_1203  acetolactate synthase isozyme II small sbunit [KO:K11258] [EC:2.2.1.6]
Xfasm12_1201  Ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
Xfasm12_0079  Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
Xfasm12_0975  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
Xfasm12_1565  aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
Xfasm12_1205  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
xfm00260  Glycine, serine and threonine metabolism
xfm00280  Valine, leucine and isoleucine degradation
xfm00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG GENES (11)   
All databases (12)   

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