KEGG   PATHWAY: ype00230
Entry
ype00230                    Pathway                                
Name
Purine metabolism - Yersinia pestis CO92 (biovar Orientalis)
Class
Metabolism; Nucleotide metabolism
Pathway map
ype00230  Purine metabolism
ype00230

Module
ype_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ype00230]
ype_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ype00230]
ype_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ype00230]
ype_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ype00230]
ype_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ype00230]
Other DBs
GO: 0006163 0042278
Organism
Yersinia pestis CO92 (biovar Orientalis) [GN:ype]
Gene
YPO0664  putative MutT-family protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
YPO0144  putative hydrolase [KO:K08312] [EC:3.6.1.-]
YPO0439  b4383; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
YPO2686  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
YPO2013  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
YPO2772  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
YPO3729  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
YPO2829  purN; putative phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
YPO1775  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
YPO2921  purI; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
YPO2828  purI; putative phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
YPO3077  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit PurK [KO:K01589] [EC:6.3.4.18]
YPO3076  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit PurE [KO:K01588] [EC:5.4.99.18]
YPO3059  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
YPO1636  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
YPO3728  purH; bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
YPO4019  putative phosphoribosyl transferase protein [KO:K00759] [EC:2.4.2.7]
YPO3123  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
YPO3358  surE; stationary-phase survival protein [KO:K03787] [EC:3.1.3.5 3.1.3.6]
YPO2624  nagD; putative N-acetylglucosamine metabolism protein [KO:K02566] [EC:3.1.3.5]
YPO0141  conserved hypothetical protein [KO:K20881] [EC:3.1.3.-]
YPO3095  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
YPO1171  pndA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
YPO0440  b4384; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
YPO3213  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
YPO3276  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
YPO3408  b0125; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
YPO2871  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
YPO2883  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
YPO0454  conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
YPO0945  conserved hypothetical protein [KO:K01519] [EC:3.6.1.66]
YPO3225  gpp; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
YPO2870  guaA; putative GMP synthase [KO:K01951] [EC:6.3.5.2]
YPO3428  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
YPO0040  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
YPO1214  dnaF; ribonucleoside-diphosphate reductase 1 alpha chain [KO:K00525] [EC:1.17.4.1]
YPO2649  nrdE; ribonucleoside-diphosphate reductase 2 alpha chain [KO:K00525] [EC:1.17.4.1]
YPO1213  ftsB; ribonucleoside-diphosphate reductase 1 beta chain [KO:K00526] [EC:1.17.4.1]
YPO2648  nrdF; ribonucleoside-diphosphate reductase 2 beta chain [KO:K00526] [EC:1.17.4.1]
YPO3454  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
YPO3383  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
YPO2559  conserved hypothetical protein [KO:K08722] [EC:3.1.3.89]
YPO0038  spoT; guanosine-3',5'-bisbis(diphosphate) 3'-pyrophosphydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
YPO2837  ppx; putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
YPO3380  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
YPO3848  cya; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
YPO1178  cyaB; adenylate cyclase 2 [KO:K05873] [EC:4.6.1.1]
YPO2696  putative 3',5'-cyclic-nucleotide phosphodiesterase [KO:K01120] [EC:3.1.4.17]
YPO0378  adeK; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
YPO2288  amn; putative AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
YPO1033  conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
YPO3530  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
YPO3118  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
YPO3378  conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
YPO0666  icc; Icc protein homologue [KO:K03651] [EC:3.1.4.53]
YPO0490  apaH; bis(5'nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
YPO3364  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
YPO3365  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
YPO3366  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
YPO3249  putative amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
YPO2667  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
YPO2666  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
YPO2665  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
YPO3261  probable amidase [KO:K22601] [EC:2.1.3.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ype00030  Pentose phosphate pathway
ype00220  Arginine biosynthesis
ype00250  Alanine, aspartate and glutamate metabolism
ype00260  Glycine, serine and threonine metabolism
ype00340  Histidine metabolism
ype00630  Glyoxylate and dicarboxylate metabolism
ype00730  Thiamine metabolism
ype00740  Riboflavin metabolism
ype00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (64)   
   KEGG GENES (64)   
All databases (65)   

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