KEGG T01656: TIA2EST2

Propionibacterium acnes TypeIA2 P.acn33: TIA2EST2_10105

Entry

TIA2EST2_10105 CDS T01656

Definition

biotin-requiring enzyme

Orthology

K00627

pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]

Organism

paz Propionibacterium acnes TypeIA2 P.acn33

Pathway

paz00010	Glycolysis / Gluconeogenesis
paz00020	Citrate cycle (TCA cycle)
paz00620	Pyruvate metabolism
paz01100	Metabolic pathways
paz01110	Biosynthesis of secondary metabolites
paz01120	Microbial metabolism in diverse environments

Module

paz_M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:paz00010]
Metabolism; Carbohydrate metabolism; Citrate cycle (TCA cycle) [PATH:paz00020]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:paz00620]

SSDB

Motif

Pfam:

2-oxoacid_dh Biotin_lipoyl E3_binding Biotin_lipoyl_2 HlyD_3 DUF3248 GCV_H

Other DBs

NCBI-GI:

365974888

NCBI-GeneID:

11491452

UniProt:

G8VD63

Position

complement(2195848..2197257)

AA seq 469 aa
MPDPGEGLTEGEVVSWRVSPGDTVKINDVLCEVETAKSIVELPSPFAGTVAKLCAEPGET
VAVGEPLVTIDDGSDDQPEEEPEFLVGHLTAESGRRRRRRRGAAVSAERAPEKAPQTPTL
KTGPETDVEPVPEPVQPTQPRRQDPPRMDRAGHVLAKPPARRVAADLGIDLSTVTGTGPQ
GAVTRSDVKAAAEAGRQAAPEPPVVGASAGDAEFATLSVMSRRLLGGAPTEPDGHTRRVP
VRGVRKVTAKAMKDSLDTKALVTAFLTCDVTPTMDLVARLRADRRFKGLRVSPLTIWCKA
VCLAMGRTPVVNARWDDAADQIVFRDQINLGIAAATPRGLMVPVVRNAQDMTMLELAEEI
TRIVAIAKEGKLQPTDYTDGTFSITNVGVFGLDAGTPVVNRTESAILVLGTIARRPWVVG
TGDDEEVVPRWVTTMSLGFDHRLIDGEEGSTFLHDVAEILSDPASAMLY

NT seq 1410 nt +upstreamnt +downstreamnt
atgccggacccgggcgaagggctcaccgagggagaggtcgtctcctggcgggtgtctccc
ggtgacaccgtcaagatcaacgacgtgctgtgcgaggtcgagacggccaagtcgatcgtc
gaactccccagccctttcgccgggaccgtggcgaagctgtgtgccgagcccggcgagacg
gtggctgtgggagagccactggtgaccattgacgacggttccgacgaccaacccgaggag
gagccggagttcctcgtcggtcacctgaccgcggagtccggacgtcgacgccgtcgtcgc
aggggagctgcggtgtcggctgaaagggcacccgagaaggccccccagacgccgaccctc
aagaccggtccagagactgatgtcgagcccgttcccgaacctgtgcagccgacacagccc
aggcgccaggatccgccgcgcatggaccgcgccgggcatgtcctcgccaagcccccggcc
cgacgtgtggctgccgacctcggcatcgacctctcgacggtgacgggcaccggcccgcag
ggggcggtgacgaggagcgacgtcaaggcggcagcggaggccggtcgtcaagccgcgcct
gaaccacctgtcgtcggtgcctctgctggcgacgctgagttcgcgaccctgtcggtgatg
tctcgtcgtctcctcggcggtgccccgaccgagcctgacggccacactcgcagggtcccg
gtgcgcggcgtccgcaaagtgactgccaaggcgatgaaggattccctggacaccaaggcc
ctcgtgacggccttcctcacctgcgacgtcaccccgacgatggacctcgtcgcccggctg
cgtgccgaccgcaggttcaagggactgcgcgtctccccgctgaccatctggtgcaaggcg
gtgtgcctggcgatgggacgcaccccggtcgtcaacgcccgctgggacgacgccgccgac
cagatcgtcttccgcgaccagatcaacctcggcatcgccgcggccaccccgcgcggcctc
atggtgcccgtggtgcgcaacgcccaggacatgacgatgctcgagctggccgaggagatc
acccgcatcgtcgccatcgccaaggagggaaagctccagcccaccgactacaccgacggc
accttctcgatcaccaatgttggggtgtttggccttgacgcagggactccggtcgtcaac
cgcaccgaatcggcgatcctcgttctcgggacgatcgctcgacgtccgtgggtcgtcggg
accggtgacgatgaggaggtcgtgcccaggtgggtgacgacgatgagcctcggcttcgac
catcgcctcattgacggcgaggagggctcgaccttcctccatgacgttgcggagattctc
tcggacccggcctcggcaatgctgtactga

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (27)   

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